AKAP12 antibody (AA 1731-1781)

Catalog No. ABIN7451614

This Rabbit Polyclonal antibody specifically detects AKAP12 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for AKAP12 antibody (AA 1731-1781) (ABIN7451614)

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP12 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-AKAP12 Antibody

Binding Specificity: AA 1731-1781

Purpose: Rabbit anti-AKAP12/Gravin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1731 and 1781

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for AKAP12

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Alternative Name: AKAP12/Gravin

Background: Background: AKAP12/Gravin is a tumor suppressor protein belonging to the A-kinase anchoring protein family. A-kinase anchoring proteins function as molecular scaffolds for the subcellular compartmentalization of A- kinase signaling molecules. In addition to its role in cell signaling, AKAP12/Gravin has also been identified as an autoantigen in some cases of myasthenia gravis and has recently been shown to play a role in leukemogenesis.

Gene ID: 9590

UniProt: Q02952

Pathways: cAMP Metabolic Process