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May be required for neuronal cell differentiation.. Additionally we are shipping AHNAK Kits (3) and AHNAK Proteins (2) and many more products for this protein.
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Human Monoclonal AHNAK Primary Antibody for ICC, IHC (f) - ABIN302097
Matza, Badou, Kobayashi, Goldsmith-Pestana, Masuda, Komuro, McMahon-Pratt, Marchesi, Flavell: A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation. in Immunity 2008
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Human Monoclonal AHNAK Primary Antibody for IP, ELISA - ABIN566328
Alli, Gower: The C type natriuretic peptide receptor tethers AHNAK1 at the plasma membrane to potentiate arachidonic acid-induced calcium mobilization. in American journal of physiology. Cell physiology 2009
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Human Polyclonal AHNAK Primary Antibody for ICC, IF - ABIN4278757
Fagerberg, Oksvold, Skogs, Algenäs, Lundberg, Pontén, Sivertsson, Odeberg, Klevebring, Kampf, Asplund, Sjöstedt, Al-Khalili Szigyarto, Edqvist, Olsson, Rydberg, Hudson, Ottosson Takanen, Berling et al.: Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP). ... in Journal of proteome research 2013
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Examination of Gene Expression Omnibus database data sets suggests that downregulation of AHNAK mRNA and mutation of the AHNAK gene are common in metastatic melanoma and correlates to a poor outcome.
inhibition of Ahnak can promote generation of induced pluripotent stem cells (iPSC) via up-regulation of endogenous c-Myc (show MYC Antibodies).
tetrandrine may inhibit the growth of Hep (show EPHB6 Antibodies)-2 cells by decreasing the intracellular concentration of Ca2 (show CA2 Antibodies)+ and upregulating the expressions of Brg1 (show SMARCA4 Antibodies) and AHNAK
Authors show here that AnxA2 (show ANXA2 Antibodies), p11 (show S100A10 Antibodies) and AHNAK are required for type 3 secretion system-mediated Salmonella invasion of cultured epithelial cells.
High AHNAK expression is asociated with mesothelioma.
While the structure-based consensus sequence allows interactions with various stretches of the AHNAK C-terminal domain, comparison with other S100 structures reveals that the sequence has been optimized for binding to S100A10 (show S100A10 Antibodies).
The AHNAK peptide adopts a coil conformation that arches across the heterotetramer contacting both annexin A2 (show ANXA2 Antibodies) and S100A10 (show S100A10 Antibodies) protomers with tight affinity.
these results define ahnak1 in muscle connective tissue as a novel feature of two genetically distinct muscular dystrophies that might contribute to disease pathology.
AHNAK constitutes a novel mechanism in post-transcriptional control of gene expression.
Multiple titin (show TTN Antibodies) antibodies, particularly those recognizing the PEVK region, cross-react with AHNAK.
Findings suggest an important role of AHNAK in the regulation of thermogenesis and lipolysis in white adipose tissue via beta-adrenergic signaling.
AHNAK plays a crucial role in body fat accumulation by regulating adipose tissue development via interaction with the SMAD1 (show SMAD1 Antibodies) protein and can be involved in metabolic homeostasis
findings suggest that Ahnak might be involved in modulating the differentiation of newly generated cells into neuronal or non-neuronal cells
Results suggest that by interfering in the cross-talk between the transmembrane form of the laminin receptor dystroglycan (show DAG1 Antibodies) and F-actin, AHNAK1 influences the cytoskeleton organization of Schwann cells
Ahnak mediates a negative regulation of cell growth and acts as novel tumor suppressor through potentiation of TGFB (show TGFB1 Antibodies) signaling.
Ahnak protein plays an important scaffolding function connecting Erk (show EPHB2 Antibodies) and Rac (show AKT1 Antibodies) activation in PDGF (show PDGFA Antibodies)-dependent migration of aortic smooth muscle cells (ASMC).
phosphorylation event is one mechanism underlying ahnak1's modulator function on Cav1.2 (show CACNA1C Antibodies) channel activity.
these results indicate that ahnak1 is not essential for beta-adrenergic up-regulation of I (CaL (show S100A11 Antibodies)) and cardiac contractility in mice.
May be required for neuronal cell differentiation.
, AHNAK nucleoprotein (desmoyokin)
, neuroblast differentiation-associated protein AHNAK