anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antibodies

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (17) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 244 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 1 to 2 Days
$135.00
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 6 to 8 Days
$335.50
Details
Dog Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$411.18
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$451.00
Details

ABCB1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies

  1. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 references for 4333368

  2. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 2 references for 317070

  3. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724923 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for 1724923

  4. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. in Human genetics 1987 (PubMed)
    Show all 2 references for 1106124

  5. Human Monoclonal ABCB1 Primary Antibody for FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

  6. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp (show ABCG2 Antibodies) and Mrp1 (show ABCC1 Antibodies) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. A subset of virus-specific CD161 (show KLRB1 Antibodies)(+) T cells selectively express the multidrug transporter MDR1 (show TBC1D9 Antibodies) and are resistant to chemotherapy in acute myeloid leukemia (show BCL11A Antibodies).

  2. Primary CD4 (show CD4 Antibodies)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (show ABCB4 Antibodies) overall activity; specific CD4 (show CD4 Antibodies)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  3. We observed an association between ABCB1 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (show PPIG Antibodies) 3A4 *1B, 3A5*3 and ABCB1 C1236T.

  4. that residual SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complexes lacking SMARCB1 (show SMARCB1 Antibodies) are vital determinants of drug sensitivity, not just to TOP2A (show TOP2A Antibodies)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1.

  5. Patients with active rheumatoid arthritis have an increased function of ABCB1 and ABCG2 (show ABCG2 Antibodies), and disease activity is the main determinant of this phenomena.

  6. the induction of P-gp (show ABCB4 Antibodies) expression is causally associated with the expression of nestin (show NES Antibodies) in leukemia cells

  7. High MDR1 (show TBC1D9 Antibodies) expression is associated with Cisplatin Resistance in Gastric Cancer.

  8. overexpression is a key Initiator of resistance to tyrosine kinase (show TXK Antibodies) inhibitors in chronic myeloid leukemia (show BCL11A Antibodies) cell lines

  9. The results indicate that human BCRP (show ABCG2 Antibodies) and not human P-gp (show ABCB4 Antibodies) is involved in benzylpenicillin transport.

  10. Study suggests thatSNPs of 1236C > T contributed to an individual variation in anesthetic effects that follow the pediatric tonsillectomy, and also it was figured out that the patients with the MDR1 1236C > T CC genotype displayed superior anesthetic effects compared to those patients who possessed the CT + TT genotype

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (show ABCB4 Antibodies) ATPase (show DNAH8 Antibodies) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

  5. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • Cd243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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