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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antibodies

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (17) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 240 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 6 to 8 Days
$335.50
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$451.00
Details

ABCB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies

  1. Dog (Canine) Polyclonal ABCB1 Primary Antibody for EIA, WB - ABIN401371 : Baker, Johnstone, Zalcberg, El-Osta: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. in Oncogene 2005 (PubMed)
    Show all 6 references for ABIN401371

  2. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 2 references for ABIN317070

  3. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 references for ABIN4333368

  4. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for ABIN1724927

  5. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. in Human genetics 1987 (PubMed)
    Show all 2 references for ABIN1106124

  6. Human Monoclonal ABCB1 Primary Antibody for FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

  7. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp (show ABCG2 Antibodies) and Mrp1 (show ABCC1 Antibodies) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. ABCB1 variant is associated with differential antiepileptic drug response in childhood absence epilepsy.

  2. Study indicates that the C3435T single-nucleotide polymorphism of the ABCB1 gene is associated with differences in the opioid sensitivity.

  3. we confirm that high P-glycoprotein (P-gp (show ABCB4 Antibodies)) expression was the strongest predictor of resistance to DAVLBH in a panel of 359 cancer cell lines.

  4. Allele C of ABCB1 and allele A of SLC22A16 (show SLC22A16 Antibodies) tended to have a greater association with grade 3/4 febrile neutropenia.

  5. Significant associations between sorafenib exposure and the studied polymorphisms were observed for ABCB1

  6. the time of manifestation of imatinib edema toxicity is found to be associated to a combination of gender and ABCB1 polymorphism

  7. Review/Meta-analysis: ABCB1-C3435T gene polymorphism might be a genetic risk factor and a potential biomarker for breast cancer.

  8. ABCB1 1236 TT genotype and older age might be a predictor of paclitaxel-induced peripheral neuropathy, which diminishes quality of life of cancer survivors

  9. The results showed high ABCB1 and ABCG2 (show ABCG2 Antibodies) gene levels, which were 4.5 and 2.3 times the levels of healthy donors, respectively.

  10. Ursolic acid exerted chemosensitizing effects in colon cancer cells under hypoxia by inhibiting HIF-1alpha accumulation and the subsequent expression of the MDR1 and VEGF

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  2. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  3. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

  4. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  5. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

  6. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin

  7. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  8. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  9. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

  10. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (show NFE2L2 Antibodies).

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • Cd243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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