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ATPase, H+ Transporting, Lysosomal Accessory Protein 1 Proteins (ATP6AP1)

ATP6AP1 encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Additionally we are shipping ATPase, H+ Transporting, Lysosomal Accessory Protein 1 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATP6AP1 537 Q15904
Mouse ATP6AP1 ATP6AP1 54411 Q9R1Q9
Rat ATP6AP1 ATP6AP1 83615 O54715
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Top ATPase, H+ Transporting, Lysosomal Accessory Protein 1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

ATP6AP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

Top referenced ATPase, H+ Transporting, Lysosomal Accessory Protein 1 Proteins

  1. Human ATP6AP1 Protein expressed in Wheat germ - ABIN1346087 : Lee, Hammerle, Andrews, Stokes, Mustelin, Silva, Black, Doedens: Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. in The Journal of biological chemistry 2011 (PubMed)

More Proteins for ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1) Interaction Partners

Human ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1) interaction partners

  1. Experimental investigation of five specific genes, AP3B1 (show AP3B1 Proteins), ATP6AP1, BLOC1S1 (show BLOC1S1 Proteins), LAMP2 (show LAMP2 Proteins), and RAB11A (show RAB11A Proteins), has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

Mouse (Murine) ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1) interaction partners

  1. The essential role of Ac45 in osteoclast-mediated extracellular acidification and protease exocytosis, as well as the ability of Ac45 to guide lysosomal intracellular trafficking to the ruffled border, is demonstrated.

  2. propose that, in addition to its canonical function in V-ATPase (show ATP6V1H Proteins)-mediated acidification, Ac45 plays versatile roles during osteoclast formation and function.

  3. These results suggest that a3 V-ATPase (show ATP6V1H Proteins) promotes distant metastasis of B16-F10 (show F10 Proteins) cells by creating acidic environments via proton secretion.

  4. Disruption of vacuolar H+-ATPase (show ATP6V1B2 Proteins) a3-B2 subunit interaction inhibited osteoclast bone resorption.

  5. Targeted disruption of the gene for the chromaffin granular V-ATPase (show ATP6V1H Proteins)-associated protein Ac45 in embryonic stem cells affects the normal blastocyst development, suggesting an essential role for the V-ATPase (show ATP6V1H Proteins) in early embryonic development. [AC45]

  6. In osteoclasts, the activity-dependent accumulation of acids and Ca(2 (show CA2 Proteins)+) in the closed extracellular compartment might serve as negative feedback signals for regulating the V-ATPase (show ATP6V1H Proteins).

  7. cytoplasmic terminus of Ac45 contains elements necessary for its proper interaction with V(0) domain and efficient osteoclastic bone resorption

  8. role for furin (show FURIN Proteins) in regulated secretion, particularly in intragranular acidification most likely due to impaired processing of Ac45

ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1) Protein Profile

Protein Summary

This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.

Gene names and symbols associated with ATP6AP1

  • ATPase, H+ transporting, lysosomal accessory protein 1 (ATP6AP1)
  • ATPase, H+ transporting, lysosomal accessory protein 1 (Atp6ap1)
  • plasma membrane proton-ATPase (PMA)
  • 16A protein
  • AC45 protein
  • AI316502 protein
  • Atp6ip1 protein
  • Atp6s1 protein
  • AW108110 protein
  • C7-1 protein
  • CF2 protein
  • H+-ATPase protein
  • mFLJ00383 protein
  • VATPS1 protein
  • XAP-3 protein
  • XAP3 protein

Protein level used designations for ATP6AP1

ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 , ATPase, H+ transporting, lysosomal interacting protein 1 , H-ATPase subunit , V-ATPase Ac45 subunit , V-ATPase S1 accessory protein , V-ATPase subunit S1 , V-type proton ATPase subunit S1 , protein XAP-3 , vacuolar proton pump subunit S1 , V-ATPase subunit Ac45 , protein C7-1 , vacuolar H+ ATPase accessory subunit 1

GENE ID SPECIES
537 Homo sapiens
54411 Mus musculus
83615 Rattus norvegicus
327687 Bos taurus
547525 Glycine max
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