anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) Antibodies

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Additionally we are shipping CD166 Kits (69) and CD166 Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALCAM 214 Q13740
ALCAM 11658 Q61490
ALCAM 79559 O35112
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Top anti-CD166 Antibodies at antibodies-online.com

Showing 10 out of 279 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD166 antibody (N-term) (ABIN389410) in NCI-H460 cell line lysates (35 µg/lane). CD166 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with CD166 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Lane 1: human colon carcinoma lysates Lane 2: rat brain lysates probed with Anti CD166 Polyclonal Antibody, Unconjugated (ABIN673944) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 64kD. Observed band size: 64kD. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Dog Goat Un-conjugated CyTOF, FACS, ICC, IHC, SimWes, WB Detection of ALCAM/CD166 in Canine PBMCs by Flow Cytometry. Canine peripheral blood mononuclear cells (PBMCs) treated with PMA and Calcium Ionomycin for 24 hours were stained with Goat Anti-Mouse/Rat/Canine ALCAM/CD166 Antigen Affinity-purified Polyclonal Antibody. Detection of ALCAM/CD166 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes either (A) activated or (B) resting were stained with Goat Anti-Mouse/Rat/Canine ALCAM/CD166 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse PE FACS Detection of ALCAM/CD166 in Human Whole Blood Lymphocytes by Flow Cytometry. Human whole blood lymphocytes were stained with Mouse Anti-Human ALCAM/CD166 PE-conjugated Monoclonal Antibody. Detection of ALCAM/CD166 in Human Whole Blood Lymphocytes by Flow Cytometry. Human whole blood lymphocytes were stained with Mouse Anti-Human ALCAM/CD166 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$294.00
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded striated muscle tissues using AlCAM mouse mAb with DAB staining. 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Mouse Goat PE FACS Detection of ALCAM/CD166 in Mouse Splenocytes by Flow Cytometry. Mouse Splenocytes either (A) activated or (B) resting were stained with Goat Anti-Mouse ALCAM/CD166 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of ALCAM/CD166 in Mouse Splenocytes by Flow Cytometry. Mouse Splenocytes either (A) activated or (B) resting were stained with Goat Anti-Mouse ALCAM/CD166 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$294.00
Details
Human Mouse Un-conjugated IHC, ELISA Figure 1: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), kidney carcinoma (B), lung carcinoma (C) and breast carcinoma (D), showing cytoplasmic and membrane localization with DAB staining using ALCAM mouse mAb. 100 μL Log in to see 2 to 3 Days
$345.40
Details
Mouse Goat Biotin FACS, IHC, WB ALCAM/CD166 in Mouse Liver. ALCAM/CD166 was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse ALCAM/CD166 Biotinylated Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm in hepatocytes. ALCAM/CD166 in Mouse Liver. ALCAM/CD166 was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse ALCAM/CD166 Biotinylated Antigen Affinity-purified Polyclonal Antibody  at 5 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Goat HRP-DAB Cell & 50 μg Log in to see 8 to 9 Days
$399.00
Details

ALCAM Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CD166 Antibodies

  1. Human Monoclonal CD166 Primary Antibody for FACS - ABIN4897157 : Soh, Zheng, Li Yeo, Yang, Ng, Wong, Zhang, Li, Nichane, Asmat, Wong, Wong, Su, Mantalaris, Lu, Xian, McKeon, Chen, Lim, Lim: CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. in Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)
    Show all 6 Pubmed References

  2. Dog (Canine) Polyclonal CD166 Primary Antibody for CyTOF, FACS - ABIN4900087 : Stanton, Beier: Inhibition of p38 MAPK signaling in chondrocyte cultures results in enhanced osteogenic differentiation of perichondral cells. in Experimental cell research 2006 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CD166 Primary Antibody for Func, IHC (fro) - ABIN2191863 : Zimmerman, Joosten, Torensma, Parnes, van Leeuwen, Figdor: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. in Blood 2006 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD166 Primary Antibody for Func, FACS - ABIN610440 : Bennett, Calakos, Scheller: Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. in Science (New York, N.Y.) 1992 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal CD166 Primary Antibody for Func, FACS - ABIN610439 : Faigle, Colucci-Guyon, Louvard, Amigorena, Galli: Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery. in Molecular biology of the cell 2000 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal CD166 Primary Antibody for IHC, ELISA - ABIN968954 : Fujiwara, Tatsumi, Kosaka, Sato, Higuchi, Yoshioka, Maeda, Ueda, Fujii: Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166). in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD166 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900084 : Ihnen, Kress, Kersten, Kilic, Choschzick, Zander, Müller, Mahner, Jänicke, Woelber, Milde-Langosch: Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients. in BMC cancer 2012 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal CD166 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900083 : Kulasingam, Zheng, Soosaipillai, Leon, Gion, Diamandis: Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer. in International journal of cancer 2009 (PubMed)
    Show all 4 Pubmed References

  9. Human Polyclonal CD166 Primary Antibody for IHC, IHC (p) - ABIN4279141 : Ishiguro, Murakami, Mizuno, Fujii, Kondo, Usami, Taniguchi, Yokoi, Osada, Sekido: Membranous expression of activated leukocyte cell adhesion molecule contributes to poor prognosis and malignant phenotypes of non-small-cell lung cancer. in The Journal of surgical research 2012 (PubMed)
    Show all 3 Pubmed References

  10. Human Monoclonal CD166 Primary Antibody for IHC (fro), FACS - ABIN2689015 : Aruffo, Bowen, Patel, Haynes, Starling, Gebe, Bajorath: CD6-ligand interactions: a paradigm for SRCR domain function? in Immunology today 1998 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD166 Interaction Partners

Zebrafish Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Alcama mediates Edn1 (show EDN1 Antibodies) signaling during zebrafish cartilage morphogenesis.

Xenopus laevis Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. The cell-adhesion molecule (show MCAM Antibodies) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (show FZD3 Antibodies) during embryonic kidney development.

Atlantic Salmon (Salmo salar) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. No significant association between ALCAM expression and survival data was observed for all tumors

Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  2. CD166 functions as a risk factor for cancers, and the alterations of its different functional isoforms were observed to correlate with specific or interplayed clinical outcomes.

  3. The results highlight the potential of ALCAM as a recurrent biomarker in early-stage endometrioid endometrial cancer and point to ALCAM as an important molecule in endometrial cancer dissemination by regulating cell migration, invasion, and metastasis.

  4. MiR (show MLXIP Antibodies)-148a and miR (show MLXIP Antibodies)-152 can sensitize tamoxifen-resistant MCF-7 breast cancer cells to tamoxifen via downregulating ALCAM.

  5. CHIP directly regulates the stability of CD166 protein through the ubiquitin proteasome system.

  6. ALCAM is overexpressed on the surface of Human T-lymphotropic virus type 1-infected lymphocytes, both in chronically infected cell lines and in primary infected CD4 (show CD4 Antibodies)(+) T lymphocytes.

  7. ALCAM is upregulated in pancreatic stellate cells of pancreatic cancer tissues, suggesting a potential role of ALCAM in regulating pancreatic cancer cell-pancreatic stellate cells interactions.

  8. PRMT1 (show PRMT1 Antibodies) is overexpressed in human melanoma, and may regulate tumor growth and metastasis via targeting ALCAM.

  9. SFMSCs increased through upregulation of the activated lymphocyte cell adhesion molecule (show MCAM Antibodies) (ALCAM) and N-cadherin (show CDH2 Antibodies) by microRNA-192 and -218 downregulation, similar to BMMSCs and ADMSCs.

  10. Analysis of KRAS mutation combined with immunohistochemical expression of CD44 (show CD44 Antibodies) and CD166 identified subgroups of patients with colon adenocarcinoma at higher risk of lymph node involvement by the tumor and development of liver and lung metastasis.

Mouse (Murine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers

  2. Data indicate that the CD166/AKT (show AKT1 Antibodies) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (show FOXO3 Antibodies) proteins in liver cancer cells.

  3. ALCAM stably interacts with actin by binding to syntenin-1 (show SDCBP Antibodies) and ezrin (show EZR Antibodies).

  4. CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (show AGER Antibodies); it shows that binding of S100B (show S100B Antibodies) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (show NFKB1 Antibodies) family members in wild type and RAGE (show AGER Antibodies)-deficient mouse endothelial cells.

  5. Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (show RUNX2 Antibodies) expression and high hematopoiesis enhancing activity.

  6. Behavioral deficits caused by prolonged IFN alpha (show IFNA Antibodies) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.

  7. novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.

  8. The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.

  9. CD166 is highly expressed within the endogenous intestinal stem cell niche

  10. The higher adhesion molecules expression and higher BBB (show ALMS1 Antibodies) permeability contributed to the major inflammatory cell infiltration into the CNS of C57BL/6 mice that was not efficient to control the parasite.

Pig (Porcine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) interaction partners

  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.

CD166 (ALCAM) Antigen Profile

Protein Summary

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene names and symbols associated with ALCAM

  • activated leukocyte cell adhesion molecule a (alcama) antibody
  • activated leukocyte cell adhesion molecule (alcam) antibody
  • activated leukocyte cell adhesion molecule (ALCAM) antibody
  • CD166 antigen homolog (cd166) antibody
  • activated leukocyte cell adhesion molecule (Alcam) antibody
  • AI853494 antibody
  • ALCAM antibody
  • BEN antibody
  • CD166 antibody
  • DM-GRASP antibody
  • JC7 antibody
  • MEMD antibody
  • MuSC antibody
  • SC1 antibody

Protein level used designations for ALCAM

CD166 antigen homolog A , DM-GRASP homolog , neurolin , neurolin-a , zn5 / zn-5 antigen , zn8 / zn-8 antigen , activated leukocyte cell adhesion molecule , CD166 antigen , DM-GRASP II , CD166 antigen-like , CD166 antigen homolog , HB2 , KG-CAM , SB-10 antigen , activated leucocyte cell adhesion molecule , BEN glycoprotein , SC1 glycoprotein

GENE ID SPECIES
30194 Danio rerio
444425 Xenopus laevis
460565 Pan troglodytes
703777 Macaca mulatta
780210 Xenopus (Silurana) tropicalis
100061848 Equus caballus
100173616 Pongo abelii
100473255 Ailuropoda melanoleuca
100286453 Salmo salar
100015168 Monodelphis domestica
100598547 Nomascus leucogenys
214 Homo sapiens
11658 Mus musculus
79559 Rattus norvegicus
281614 Bos taurus
396092 Gallus gallus
100009305 Oryctolagus cuniculus
478550 Canis lupus familiaris
397269 Sus scrofa
100726386 Cavia porcellus
101114151 Ovis aries
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