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Activin A Receptor, Type IB Proteins (ACVR1B)

ACVR1B encodes an activin A type IB receptor. Additionally we are shipping Activin A Receptor Type IB Antibodies (132) and Activin A Receptor Type IB Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACVR1B 11479 Q61271
ACVR1B 91 P36896
ACVR1B 29381 P80202
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Top Activin A Receptor Type IB Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag 200 μg Log in to see 2 to 3 Days
$275.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Cynomolgus Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ACVR1B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
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Human , , , , , , ,
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Rat (Rattus) ,
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Top referenced Activin A Receptor Type IB Proteins

  1. Human Activin A Receptor Type IB Protein expressed in HEK-293 Cells - ABIN2180556 : Cárcamo, Weis, Ventura, Wieser, Wrana, Attisano, Massagué: Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. in Molecular and cellular biology 1994 (PubMed)
    Show all 3 references for ABIN2180556

More Proteins for Activin A Receptor, Type IB (ACVR1B) Interaction Partners

Mouse (Murine) Activin A Receptor, Type IB (ACVR1B) interaction partners

  1. Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation

  2. These results indicate that an appropriate level of activin signaling may be required for GSIS in pancreatic beta cells, and that activin signaling involves modulation of KATP channel activity.

  3. Signaling through the TGF beta (show TGFB1 Proteins)-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

  4. identified ACVRIB as a direct target of miR (show MLXIP Proteins)-145. The ectopic expression of miR (show MLXIP Proteins)-145 reduced the levels of both ACVRIB mRNA and protein and also interfered with activin-induced Smad2 (show SMAD2 Proteins) phosphorylation.

  5. Results identify a molecular mechanism that explains the cell-type specific aspects of signaling by myostatin (show MSTN Proteins), ALK4, ALK5 (show TGFBR1 Proteins), and other TGF-beta (show TGFB1 Proteins) family members.

  6. Inhibin alpha-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.

  7. Knockdown or pharmacological inhibition of the Nodal/Activin receptor Alk4/7 in cancer stem cells virtually abrogated their self-renewal capacity and in vivo tumorigenicity

  8. Our analysis of this Acvr1b knockout mouse line provides direct genetic evidence that Acvr1b signaling is required for both hair follicle development and cycling.

  9. analysis of expression and cellular compartmentalization of the activin receptors ActRIIA, ActRIIB and ActRIB, the inhibin co-receptor (betaglycan), and activin signaling proteins Smads 2, 3 and 4, and growth regulatory role during lactation

  10. Alk4 is expressed in the early development of thymocytes.

Human Activin A Receptor, Type IB (ACVR1B) interaction partners

  1. ALK4 is expressed in male germ cells and Sertoli cells.

  2. This study demonstrated positive regulation of monocyte/macrophage differentiation by lnc-MC and uncovered an elaborate regulation mechanism composed of PU.1, lnc-MC, miR (show MLXIP Proteins)-199a-5p, and ACVR1B.

  3. Data suggest that activin A (show INHBA Proteins) up-regulates SNAIL (show SNAI1 Proteins) expression via ALK4/ACVR1B-induced SMAD (show SMAD1 Proteins) signaling in trophoblast cells; elevated SNAIL (show SNAI1 Proteins) contributes to up-regulation of MMP2 (show MMP2 Proteins) expression which plays key role in promoting trophoblast cell invasion.

  4. ACVR1B functions as a positive regulator of monocyte/macrophage differentiation. ACVR1B knockdown promoted THP-1 proliferation by increasing Rb phosphorylation. Down-regulation reduced p-Smad2 (show SMAD2 Proteins)/3 and C/EBPalpha (show CEBPA Proteins), inhibiting monocyte/macrophage differentiation.

  5. The deletion of the ACVR1B gene may mediate an aggressive cancer phenotype in pancreatic cancer.

  6. Findings define a regulatory role of miR (show MLXIP Proteins)-98 in tumor angiogenesis and invasion through repressed ALK4 and MMP11 (show MMP11 Proteins) expression.

  7. ActRIBCA signaling can promote cell migration in prostate cancer cells via a network of signaling molecules that work together to trigger the process of EMT (show ITK Proteins), and thereby aid in the aggressiveness and progression of prostate cancers.

  8. Act A protein levels were significantly higher in NTM (show NTM Proteins) tissues compared to GTM tissues.

  9. Inhibin alpha-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.

  10. Activin A (show INHBA Proteins)-ACVRIB/ALK4-Smad (show SMAD1 Proteins)-dependent collagen production was augmented in SSc (show CYP11A1 Proteins) fibroblasts, suggesting the involvement of this signaling mechanism in systemic sclerosis.

Activin A Receptor Type IB (ACVR1B) Protein Profile

Protein Summary

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ACVR1B

  • activin A receptor, type IB (ACVR1B)
  • activin A receptor, type IB (acvr1b)
  • Activin receptor type-1B (acv1b)
  • activin A receptor, type 1B (Acvr1b)
  • activin A receptor, type IB (Acvr1b)
  • 6820432J04 protein
  • ActR-IB protein
  • ACTRIB protein
  • ACVR1B protein
  • ACVRLK4 protein
  • alk-4 protein
  • ALK4 protein
  • axis protein
  • DKFZp469A1614 protein
  • Skr2 protein
  • taram-a protein
  • tarama protein
  • wu:fb75f01 protein
  • xalk4 protein

Protein level used designations for ACVR1B

activin A receptor, type IB , activin A receptor, type 1B , activin type IB receptor , activin receptor type-1B-like , Activin receptor type-1B , activin receptor IB , ALK-4 , activin receptor type IB , activin receptor type-1B , activin receptor-like kinase 4 , serine/threonine-protein kinase receptor R2 , activin A receptor, type II-like kinase 4 , ACTR-IB , Serine/threonine-protein kinase receptor R2

GENE ID SPECIES
100062619 Equus caballus
451911 Pan troglodytes
733849 Xenopus (Silurana) tropicalis
768878 Gallus gallus
100391614 Callithrix jacchus
100482103 Ailuropoda melanoleuca
100195539 Salmo salar
443254 Ovis aries
100173725 Pongo abelii
11479 Mus musculus
91 Homo sapiens
29381 Rattus norvegicus
30183 Danio rerio
486537 Canis lupus familiaris
100152462 Sus scrofa
539315 Bos taurus
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