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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) Antibodies

The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. Additionally we are shipping Advanced Glycosylation End Product-Specific Receptor Kits (77) and Advanced Glycosylation End Product-Specific Receptor Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGER 177 Q15109
AGER 11596  
AGER 81722  
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Top anti-Advanced Glycosylation End Product-Specific Receptor Antibodies at antibodies-online.com

Showing 10 out of 299 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-AGER Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate Lanes: Lane 1:141 µg of hRAGE HEK-293 lysate  Lane 2: 141 µg of mRAGE HEK-293 lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:0500  Gene Name: AGER Submitted by: Barry Hudson 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-AGER Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemical analysis of Paraffin-Embedded Rat Tissue Sections (Lung) using RAGE antibody. Western blot analysis of rat lung tissue lysis using RAGE antibody 0.2 mL Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of RAGE Antibody (Center) in mouse liver tissue lysates (35ug/lane). RAGE (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of RAGE (arrow) using rabbit polyclonal RAGE Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RAGE gene (Lane 2) . 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-MOK Pab in A375 cell lysate. MOK (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of AGER Antibody (N-term) (ABIN651054) in mouse lung tissue lysates (35 µg/lane). AGER (arrow) was detected using the purified polyclonal antibody. AGER Antibody (N-term) (ABIN651054) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of AGER-K44 (ABIN389027) in mouse lung tissue lysates (35 µg/lane).AGER (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of RAGE Antibody (Center) (ABIN390897) in mouse liver tissue lysates (35 µg/lane). RAGE (arrow) was detected using the purified polyclonal antibody. Western blot analysis of RAGE (arrow) using rabbit polyclonal RAGE Antibody (Center) (ABIN390897). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the RAGE gene (Lane 2) . 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB   0.1 mL Log in to see 10 to 12 Days
$623.70
Details

AGER Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Advanced Glycosylation End Product-Specific Receptor Antibodies

  1. Cow (Bovine) Polyclonal AGER Primary Antibody for EIA, IHC (p) - ABIN264840 : Sugars, Karlström, Christersson, Olsson, Wendel, Fried: Expression of HMGB1 during tooth development. in Cell and tissue research 2007 (PubMed)
    Show all 5 references for ABIN264840

  2. Human Polyclonal AGER Primary Antibody for IHC (p), WB - ABIN389027 : Schlueter, Hauke, Flohr, Rogalla, Bullerdiek: Tissue-specific expression patterns of the RAGE receptor and its soluble forms--a result of regulated alternative splicing? in Biochimica et biophysica acta 2003 (PubMed)
    Show all 4 references for ABIN389027

  3. Human Polyclonal AGER Primary Antibody for IF, IHC (p) - ABIN1108826 : Bierhaus, Haslbeck, Humpert, Liliensiek, Dehmer, Morcos, Sayed, Andrassy, Schiekofer, Schneider, Schulz, Heuss, Neundörfer, Dierl, Huber, Tritschler, Schmidt, Schwaninger, Haering, Schleicher, Kasper et al.: Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. ... in The Journal of clinical investigation 2004 (PubMed)
    Show all 4 references for ABIN1108826

  4. Human Polyclonal AGER Primary Antibody for EIA, IHC (p) - ABIN357685 : Shanmugam, Kim, Lanting, Natarajan: Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN357685

  5. Human Polyclonal AGER Primary Antibody for EIA, IHC (p) - ABIN359696 : Miyata, Akashi, Nishida: Molecular cloning and characterization of a novel member of the MAP kinase superfamily. in Genes to cells : devoted to molecular & cellular mechanisms 1999 (PubMed)
    Show all 2 references for ABIN359696

  6. Human Polyclonal AGER Primary Antibody for WB - ABIN2776831 : Galichet, Weibel, Heizmann: Calcium-regulated intramembrane proteolysis of the RAGE receptor. in Biochemical and biophysical research communications 2008 (PubMed)

  7. Human Polyclonal AGER Primary Antibody for IF, WB - ABIN390897 : Peng, Lu, Wang, Yan, Chen, Zhang, Zhang, Shen: RAGE gene polymorphisms are associated with circulating levels of endogenous secretory RAGE but not with coronary artery disease in Chinese patients with type 2 diabetes mellitus. in Archives of medical research 2009 (PubMed)

  8. Human Polyclonal AGER Primary Antibody for FACS, IHC (p) - ABIN651054 : Rojas, Figueroa, Morales: Fueling inflammation at tumor microenvironment: the role of multiligand/RAGE axis. in Carcinogenesis 2010 (PubMed)

  9. Human Polyclonal AGER Primary Antibody for IHC, WB - ABIN2776917 : Lieuw-a-Fa, Schalkwijk, Engelse, van Hinsbergh: Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs. in Thrombosis and haemostasis 2006 (PubMed)

More Antibodies against Advanced Glycosylation End Product-Specific Receptor Interaction Partners

Human Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. Genotyping of a Euro-Brazilian population of children and adolescents with type 1 diabetes showed no significant differences in the -429T>C, -374T>A and 63 bp deletion/insertion (-407 to -345 bp) in RAGE promotor when compared to control.

  2. Multi-walled carbon nanotube induces injury or necrosis of lung epithelial cells and DNA damage via HMGB1 (show HMGB1 Antibodies)/RAGE/TLR9 (show TLR9 Antibodies) pathway.

  3. In conclusion, these data indicated that common polymorphisms in the AGER gene might increase the risks of breast (BC) and lung (LC) cancer .

  4. We conclude that placental RAGE is activated during preeclampsia and that RAGE-mediated inflammation in the trophoblast involves increased pro-inflammatory cytokine secretion.

  5. increased plasma level of soluble RAGE is a better indicator of renal function decline in diabetic CKD patients instead of non-diabetic CKD patients

  6. Study describes evidence for the role of HMGB1 (show HMGB1 Antibodies)-RAGE and the HMGB1 (show HMGB1 Antibodies)-TLR4 (show TLR4 Antibodies) axis associated with pulmonary dysfunction and central nervous system injury. [review]

  7. Single nucleotide polymorphisms (SNPs) rs1035798 in RAGE gene, rs2073617 and rs2073618 in TNFRSF11B (show TNFRSF11B Antibodies), and rs3732410 in Golgb1 (show GOLGB1 Antibodies) will be investigated on whether there is an association with hemorrhagic stroke (HS) in Chinese population.

  8. These results indicate that RAGE may be a potential trigger in microvascular formation and proliferation in the development of endometrial cancer.

  9. This present study confirmed an important role of RAGE in vivo and vitro models of pulmonary fibrosis and suggested the therapeutic possibility for pulmonary fibrosis via RAGE regulation

  10. Reduced expression of membrane-bound AGER is a biomarker of multiple sclerosis disease progression.

Cow (Bovine) Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. Our results suggested that the increased RAGE expression in inflammatory circumstances and interaction with AGEs are risk factors in decreasing of aggrecan (show ACAN Antibodies) content in nucleus pulposus.

Mouse (Murine) Advanced Glycosylation End Product-Specific Receptor (AGER) interaction partners

  1. This present study confirmed an important role of RAGE in vivo and vitro models of pulmonary fibrosis and suggested the therapeutic possibility for pulmonary fibrosis via RAGE regulation

  2. beta-Caryophyllene protects against GalN (show GAL Antibodies)/LPS (show TLR4 Antibodies)-induced liver injury through down-regulation of the TLR4 (show TLR4 Antibodies) and RAGE signaling.

  3. AGER and its functions to stimulate O-GlcNAcylation are important during liver tumorigenesis, when high blood glucose levels are inadequately controlled.

  4. HMGB1 (show HMGB1 Antibodies) and its main receptor, RAGE, appear to be crucial factors in the pathogenesis of TnI (show TNNI2 Antibodies)-induced experimental autoimmune myocarditis.

  5. Only one fragment RAGE (60-76) was shown to have a therapeutic activity improving the memory state of bulbectomized mice and leads to decreasing in the level of brain beta-amyloid.

  6. These data implicate RAGE as a modulator of both vasoreactivity and of proliferative processes in the response of the pulmonary circulation to chronic-hypoxia.

  7. activation of the RAGE by advanced glycation end products or other ligands suppresses NIPP1 (show PPP1R8 Antibodies) expression in diabetic nephropathy, contributes to podocyte hypertrophy, and glomerular inflammation

  8. RAGE-/- mice showed reduced inflammation, lower Th2 cytokine production from mononuclear cells, and lower numbers of group 2 innate lymphoid cells in the lung compared with RAGE+/+ mice.

  9. Mice expressing RAGE on hematopoietic cells, but not radioresistant structural cells, showed reduced neutrophilia and emphysematous change in the lung.

  10. RAGE has a role in pathogenesis of emphysema in mice.

Advanced Glycosylation End Product-Specific Receptor (AGER) Antigen Profile

Protein Summary

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).

Gene names and symbols associated with AGER

  • advanced glycosylation end product-specific receptor (AGER) antibody
  • advanced glycosylation end product-specific receptor (Ager) antibody
  • advanced glycosylation end product-specific receptor (LOC100343142) antibody
  • AGER antibody
  • RAGE antibody

Protein level used designations for AGER

advanced glycosylation end product-specific receptor , RAGE isoform NtRAGE-delta , RAGE isoform sRAGE-delta , RAGE/AGER , advanced glycation end product receptor , advanced glycosylation end product-specific receptor variant 1 , advanced glycosylation end product-specific receptor variant 3 , advanced glycosylation end product-specific receptor variant 4 , advanced glycosylation end product-specific receptor variant 5 , advanced glycosylation end product-specific receptor variant 6 , advanced glycosylation end product-specific receptor variant 7 , advanced glycosylation end product-specific receptor variant 8 , receptor for advanced glycosylation end products , advanced glycation end-products receptor , advanced glycosylation end product-specific receptor variant 2

GENE ID SPECIES
462584 Pan troglodytes
177 Homo sapiens
403168 Canis lupus familiaris
396591 Sus scrofa
280986 Bos taurus
11596 Mus musculus
81722 Rattus norvegicus
100343142 Oryctolagus cuniculus
100726130 Cavia porcellus
101111586 Ovis aries
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