anti-Alkaline Phosphatase, Intestinal (ALPI) Antibodies

ALPI encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. Additionally we are shipping Intestinal Alkaline Phosphatase Kits (40) and Intestinal Alkaline Phosphatase Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALPI 248 P09923
ALPI 24197  
ALPI 76768  
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Top anti-Intestinal Alkaline Phosphatase Antibodies at antibodies-online.com

Showing 10 out of 280 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of ALPI Antibody (Center) (ABIN388283) in HL60 cell line lysates (35 µg/lane). ALPI (arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB 100 μg Log in to see 2 to 3 Days
$430.10
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells, using XIAP (Ab-87) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using XIAP (Ab-87) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells treated with Anisomycin 25ug/ml 30', using XIAP (Phospho-Ser87) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using XIAP (Phospho-Ser87) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL Log in to see 12 to 15 Days
$518.65
Details
Human Rabbit Un-conjugated ELISA, WB Western Blot: Alkaline Phosphatase, Intestinal Antibody [ABIN153475] - Both the antiserum and IgG fractions of anti-Alkaline Phosphatase (Human Intestine) are shown to detect under reducing conditions of SDS-PAGE the 60,000 dalton enzyme in cellular extracts. Approximately 10 ug of total protein is loaded per lane. A 1:5,000 dilution of the primary antibody is used followed by detection using HRP Goat-a-Rabbit IgG [H&L] diluted 1:4,000 and color development using 4-CN substrate until sufficient color develops. 0.2 mL Log in to see 7 to 9 Days
$301.88
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), IP, WB 50 μL Log in to see 6 to 8 Days
$368.50
Details
Human Mouse Un-conjugated ELISA, WB ALPI monoclonal antibody (M03), clone 3A8 Western Blot analysis of ALPI expression in HeLa . Detection limit for recombinant GST tagged ALPI is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Goat Un-conjugated IHC (p) Small intestine, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, WB   2 mL Log in to see 12 to 15 Days
$1,696.37
Details

ALPI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,


Mouse (Murine) ,


Top referenced anti-Intestinal Alkaline Phosphatase Antibodies

  1. Human Polyclonal Intestinal Alkaline Phosphatase Primary Antibody for ELISA, WB - ABIN153475 : Wilson, Byun, Popova, Murray, LItalien, Sowa, Arango, Velcich, Augenlicht, Mariadason: Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for FACS, ELISA - ABIN1724815 : Molnár, Vannay, Sziksz, Bánki, Gy?rffy, Arató, Dezs?fi, Veres: Decreased mucosal expression of intestinal alkaline phosphatase in children with coeliac disease. in Virchows Archiv : an international journal of pathology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for FACS, ELISA - ABIN1724814 : Molnár, Vannay, Szebeni, Bánki, Sziksz, Cseh, Gy?rffy, Lakatos, Papp, Arató, Veres: Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease. in World journal of gastroenterology : WJG 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal Intestinal Alkaline Phosphatase Primary Antibody for IF, WB - ABIN388283 : Hendarto, Prabowo, Moeloek, Soetjipto: Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis. in Fertility and sterility 2010 (PubMed)

  5. Human Monoclonal Intestinal Alkaline Phosphatase Primary Antibody for ELISA, WB - ABIN559857 : Lechner, Reichel, Moenning, Reichel, Fricker: Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010 (PubMed)

More Antibodies against Intestinal Alkaline Phosphatase Interaction Partners

Human Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Data indicate alkaline phosphatase (AP) as the primary soluble ectonucleotidase in infants undergoing cardiopulmonary bypass and show decreased capacity to clear AMP (show APRT Antibodies) when AP activity decreases post-bypass.

  2. Intestinal alkaline phosphatase is a major regulator of gut (show GUSB Antibodies) mucosal permeability and appears to work at least partly through improving tight junction protein (show OCLN Antibodies) levels and localization.

  3. A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity

  4. Review of the role of intestinal alkaline phosphatase in inflammatory diseases. Loss of IAP expression or function is associated with increased intestinal inflammation, dysbiosis, bacterial translocation and subsequently systemic inflammation.

  5. The expression of ALPi and MUC5AC in cocultures of Caco-2 and HT29 cells developed for permeability studies is reported.

  6. Data indicate that histone deacetylase (show HDAC1 Antibodies) inhibitors (HDACi) induce intestinal alkaline phosphatase (ALPi) in a subset of colon cancer cell lines in a Kruppel-like factor 5 (KLF5 (show KLF5 Antibodies))-dependent manner.

  7. Report lowered intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease.

  8. we are the first to demonstrate the alteration of protein expression of iAP in the duodenal mucosa of children with newly diagnosed coeliac disease

  9. Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS (show IRF6 Antibodies), CpG DNA, and flagellin (show FliC Antibodies), and not on live bacteria. IAP likely targets these bacterially derived molecules as gut (show GUSB Antibodies) mucosal defense factor.

  10. intestinal alkaline transactivation by Kruppel-like factor-4 (show KLF4 Antibodies) is likely mediated through a critical region located within the proximal IAP promoter region

Mouse (Murine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Intestinal alkaline phosphatase is a major regulator of gut (show GUSB Antibodies) mucosal permeability and appears to work at least partly through improving tight junction protein (show OCLN Antibodies) levels and localization.

  2. Authors found that Akp3(-/-) mice acquired lipopolysaccharide tolerance during postweaning development, suggesting that Akp3 plays an important role in immune education.

  3. Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

  4. It is concluded that CD36 (show CD36 Antibodies) exists in its phosphorylated and dephosphorylated states in mouse enterocytes and that pCD36 is a substrate of global intestinal alkaline phosphatase (gIAP).

  5. These data suggest that IAP is a local immunomodulating factor, perhaps regulating LPS-toll-like receptor 4 (show TLR4 Antibodies) (TLR4 (show TLR4 Antibodies)) interaction between commensal microflora and intestinal epithelium.

  6. Suggest role for lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

  7. Results suggest that intestinal alkaline phosphatase participates in a rate-limiting step regulating fat absorption.

  8. forced high-fat chow induced an 18% greater body weight gain, hepatic steatosis, and visceral fat accumulation in female Akp3(-/-) mice but not in female wild-type controls. there is 2X increase of lipid absorption in Akp3(-/-) male mice.

  9. Intestinal alkaline phosphatase activity may have a role in mediating the accelerated fatty acid intake observed in Akp3 knockout mice fed a high-fat diet.

Cow (Bovine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS (show IRF6 Antibodies), CpG DNA, and flagellin (show FliC Antibodies), and not on live bacteria. IAP likely targets these bacterially derived molecules as gut (show GUSB Antibodies) mucosal defense factor.

  2. Secondary structure of CIP after reaction with Co2+ in different conditions.

Intestinal Alkaline Phosphatase (ALPI) Antigen Profile

Protein Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation.

Gene names and symbols associated with ALPI

  • alkaline phosphatase, intestinal (ALPI) antibody
  • alkaline phosphatase, intestinal (Alpi) antibody
  • alkaline phosphatase, intestinal, tandem duplicate 1 (alpi.1) antibody
  • alkaline phosphatase, placental like 2 (ALPPL2) antibody
  • alkaline phosphatase 3, intestine, not Mn requiring (Akp3) antibody
  • intestinal-type alkaline phosphatase (LOC100724954) antibody
  • 2010001C14Rik antibody
  • Akp-3 antibody
  • Akp6 antibody
  • Alp1 antibody
  • Alpi antibody
  • dIAP antibody
  • gIAP antibody
  • IAP antibody
  • im:7149588 antibody
  • S51097 antibody
  • si:ch211-262h13.1 antibody
  • wu:fa95f04 antibody
  • zgc:110794 antibody

Protein level used designations for ALPI

Kasahara isozyme , alkaline phosphomonoesterase , glycerophosphatase , intestinal alkaline phosphatase , intestinal-type alkaline phosphatase , Alkaline phosphatase 1, intestinal, defined by SSR , IAP-1 , IAP-I , intestinal alkaline phosphatase 1 , intestinal alkaline phosphatase I IAP-I , intestinal-type alkaline phosphatase 1 , alkaline phosphatase 6 , intestinal alkaline phosphatase V , alkaline phosphatase, intestinal.1 , iap , alkaline phosphatase, intestinal , intestinal-type alkaline phosphatase-like

GENE ID SPECIES
248 Homo sapiens
24197 Rattus norvegicus
76768 Mus musculus
280993 Bos taurus
424936 Gallus gallus
541539 Danio rerio
100399082 Callithrix jacchus
100437471 Pongo abelii
100465399 Ailuropoda melanoleuca
403736 Canis lupus familiaris
740585 Pan troglodytes
11648 Mus musculus
100724954 Cavia porcellus
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