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The protein encoded by APBB1 is a member of the Fe65 protein family. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) Proteins (8) and Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) Kits (4) and many more products for this protein.
Showing 10 out of 107 products:
Human Polyclonal APBB1 Primary Antibody for ELISA, WB - ABIN185689
Hoe, Magill, Guenette, Fu, Vicini, Rebeck: FE65 interaction with the ApoE receptor ApoEr2. in The Journal of biological chemistry 2006
Jagged1 is a novel binding partner of Fe65, and Fe65 may act as a novel effector of Jagged1 signaling.
results provide strong evidence that Fe65 plays a role in DNA damage response and cell viability by epigenomic regulation of specific transcriptional programs activated upon genotoxic stress.
Findings show that amyloid precursor protein (show APP Antibodies)-binding proteins FE65 and FE65L1 (show APBB2 Antibodies) are essential for the maintenance of lens transparency.
our data suggest that FE65 serves as a link between VLDLR (show VLDLR Antibodies) and APP (show APP Antibodies)
FE65 small interfering RNA does not influence Rac1 expression or its activity, although it acts as an adaptor protein with several protein-interaction domains.
Fe65 carries out different functions depending on its location in the regulation of Notch1 (show NOTCH1 Antibodies) signaling.
a unique role for the 97 kDa isoform in controlling GnRH-1 (show GNRH1 Antibodies) neurogenesis that is not redundant with the 60 kDa isoform of FE65.
Results confirm that megalin (show LRP2 Antibodies) interacts with APP (show APP Antibodies) and FE65, suggesting that these three proteins form a tripartite complex.
Data show that the carboxyl-terminal half of FE65, which contains the PI2 (show SERPINB1 Antibodies) domain, failed to stabilize p53 (show TP53 Antibodies), suggesting that the amino-terminal half of the protein plays an important role in the stabilization of p53 (show TP53 Antibodies) in osmotically stressed cells.
cell cycle progression by down-regulating thymidylate synthase (show TYMS Antibodies) expression
Targeted enhancement of the signaling through the Fe65-cortactin (show CTTN Antibodies) pathway, by either HDAC6 (show HDAC6 Antibodies) inhibition or Tip60 (show KAT5 Antibodies) activation, may lead to the development of new therapeutic drugs that are effective for patients with metastatic breast cancers.
FE65 influences APP (show APP Antibodies) degradation via the proteasome, and phosphorylation of FE65 Ser (show SIGLEC1 Antibodies)(610) by SGK1 (show SGK1 Antibodies) regulates binding of FE65 to APP (show APP Antibodies), APP (show APP Antibodies) turnover and processing.
A novel phosphorylation site was identified within Fe65 which mediates gene transcription.
The SV2A (show SV2A Antibodies)/FE65 interaction might play a role in synaptic signal transduction.
Data indicate that Fe65 is a positive estrogen receptor alpha (ERalpha (show ESR1 Antibodies)) transcriptional regulator.
FE65 interactions with BLM and MCM proteins may contribute to the neuronal cell cycle re-entry observed in brains affected by Alzheimer's disease.
A ternary complex consisting of AICD, FE65, and TIP60 (show KAT5 Antibodies) down-regulates Stathmin1.
Both amyloid-beta precursor protein and Fe65 are co-localized in model Hirano bodies associated with Alzheimer's disease.
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
, amyloid beta A4 precursor protein-binding, family B, member 1
, amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
, amyloid beta A4 precursor protein-binding family B member 1-like
, amyloid beta A4 precursor protein-binding family B member 1
, adaptor protein FE65a2
, stat-like protein
, amyloid beta precursor protein-binding B1