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The protein encoded by ANKRD15 belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. Additionally we are shipping and many more products for this protein.
Showing 10 out of 20 products:
Human Monoclonal ANKRD15 Primary Antibody for ELISA, WB - ABIN395383
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 5 references for ABIN395383
Data suggest that Kank negatively regulates the formation of actin stress fibers and cell migration through the inhibition of RhoA (show RHOA Antibodies) activity, which is controlled by binding of Kank to 14-3-3 (show YWHAQ Antibodies) in PI3K-Akt (show AKT1 Antibodies) signaling.
primary results revealed new function of Kank1 for nasopharyngeal cancer
identified recessive mutations in kidney ankyrin repeat-containing protein 1 (KANK1), KANK2, and KANK4 in individuals with nephrotic syndrome.
Follow-up replication analyses in up to an additional 21,345 participants identified three new fasting plasma glucose loci reaching genome-wide significance in or near PDK1 (show PDK1 Antibodies)-RAPGEF4 (show RAPGEF4 Antibodies), KANK1, and IGF1R (show IGF1R Antibodies).
Thus, the human brain glioma apoptosis induced by upregulation of the Kank1 gene is closely relevant to the mitochondrial pathway.
Our case suggests that KANK1 may be subject to random monoallelic expression as a possible mode of inheritance.
ANKRD15 encodes the kidney ankyrin repeat-containing protein.
BIG1 (show CNTN3 Antibodies) and KANK1 play roles in regulating cell polarity during directed migration in wound healing.
KANK1, a candidate tumor suppressor gene, is fused to PDGFRB (show PDGFRB Antibodies) in an imatinib-responsive myeloid neoplasm with severe thrombocythemia.
Kank is localized to 9p24 and plays a role in cell growth
Human Kank gene has several alternative first exons.
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5\;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseuodgene has been identified on chromosome 20.
KN motif and ankyrin repeat domain-containing protein 1
, ankyrin repeat domain 15
, KN motif and ankyrin repeat domains 1
, KN motif and ankyrin repeat domains 1, gene 1
, KN motif and ankyrin repeat domains 1, gene 2
, ankyrin repeat domain protein 15
, ankyrin repeat domain-containing protein 15
, kidney ankyrin repeat-containing protein