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anti-Arachidonate 15-Lipoxygenase (ALOX15) Antibodies

demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity. Additionally we are shipping Arachidonate 15-Lipoxygenase Kits (13) and Arachidonate 15-Lipoxygenase Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX15 246 P16050
ALOX15 11687 P39654
ALOX15 81639 Q02759
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Top anti-Arachidonate 15-Lipoxygenase Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ALOX15 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Formalin-fixed and paraffin-embedded human lymph tissue reacted with ALOX15 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. ALOX15 Antibody (C-term) (ABIN392383) western blot analysis in Hela,A549,K562,MDA-MB435 cell line lysates (35 µg/lane).This demonstrates the ALOX15 antibody detected the ALOX15 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-ALOX15 mouse monoclonal antibody (ABIN2455602) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALOX15 (RC206621). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX15 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX15. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB ALOX15 monoclonal antibody (M04), clone 3D8 Western Blot analysis of ALOX15 expression in Hela NE on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 1.5 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated ELISA, WB ABIN334342 (0.2µg/ml) staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ALOX15 Picoband antibody,  IHC(P): Mouse Lung Tissue Anti-ALOX15 Picoband antibody,  IHC(P): Human Intestine Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC206621 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ALOX15 antibody (ABIN2455497), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX15 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX15. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALOX15 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ALOX15. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB ALOX15 monoclonal antibody (M04), clone 3D8 Western Blot analysis of ALOX15 expression in Hela S3 NE . Immunoperoxidase of monoclonal antibody to ALOX15 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.5 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details

ALOX15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Arachidonate 15-Lipoxygenase Antibodies

  1. Human Monoclonal ALOX15 Primary Antibody for WB - ABIN395968 : Zhang, Wang, Liu, Wang, Liu, Ma, Gong, Li: Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population. in Heart and vessels 2010 (PubMed)
    Show all 5 references for ABIN395968

  2. Human Monoclonal ALOX15 Primary Antibody for IHC (p), ELISA - ABIN513270 : Calandria, Marcheselli, Mukherjee, Uddin, Winkler, Petasis, Bazan: Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN513270

  3. Human Monoclonal ALOX15 Primary Antibody for FACS, IF - ABIN2455602 : Fredman, Li, Dalli, Chiang, Serhan: Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA. in Scientific reports 2012 (PubMed)
    Show all 3 references for ABIN2455602

  4. Human Polyclonal ALOX15 Primary Antibody for IF, IHC (p) - ABIN392383 : Tang, Wang, Chen, Yang, Che, Honn, Akers, Johnson, Nie: Downregulation of vascular endothelial growth factor and induction of tumor dormancy by 15-lipoxygenase-2 in prostate cancer. in International journal of cancer. Journal international du cancer 2009 (PubMed)
    Show all 2 references for ABIN392383

  5. Human Polyclonal ALOX15 Primary Antibody for IHC, ELISA - ABIN2159070 : Starowicz, Makuch, Korostynski, Malek, Slezak, Zychowska, Petrosino, De Petrocellis, Cristino, Przewlocka, Di Marzo: Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. in PLoS ONE 2013 (PubMed)

  6. Human Polyclonal ALOX15 Primary Antibody for ELISA, WB - ABIN334342 : McDuffie, Maybee, Keller, Stevens, Garmey, Morris, Kropf, Rival, Ma, Carter, Tersey, Nunemaker, Nadler: Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes. in Diabetes 2007 (PubMed)

  7. Cow (Bovine) Polyclonal ALOX15 Primary Antibody for WB - ABIN2786489 : McCaskie, Beilby, Hung, Chapman, McQuillan, Powell, Thompson, Palmer: 15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intima-media thickness. in Human genetics 2008 (PubMed)

More Antibodies against Arachidonate 15-Lipoxygenase Interaction Partners

Pig (Porcine) Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. The crystal structure of a mammalian 12-lipoxygenase reveals a plausible substrate access channel for oxygen.

  2. 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter (show ABCA13 Antibodies) G1.

  3. EPR (show EREG Antibodies) spectroscopy and electrospray mass spectroscopy reveal distinctive features of the iron site in leukocyte arachidonate 12-lipoxygenase (show ALOX12 Antibodies).

Human Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. Hypoxia increase the production of ROS (show ROS1 Antibodies) through the 15-Lipoxygenase/15-Hydroxyeicosatetraenoiccid pathway.

  2. The role of 15-LOX-1 in colitis and colitis-associated colorectal cancer

  3. variation in inflammation related genes ALOX15 and IL6 (show IL6 Antibodies) was associated with bone microarchitecture and density in young adult women, but appears to be less important in the elderly

  4. Significant associations with NSAID-exacerbated respiratory disease were identified for: ALOX15 homozygous genotype and PTGS-1 (show PTGS1 Antibodies) rs5789 A/A homozygous genotype

  5. limiting ALOX15 expression by AMPK (show PRKAA1 Antibodies) may promote an anti-inflammatory phenotype of IL-4 (show IL4 Antibodies)-stimulated human macrophages

  6. Effect of 12/15-LOX on colorectal tumorigenesis in mouse models could be affected by tumor cell type (human or mouse), relative 12/15 LOX activity in tumor cells and stroma as well as the relative tumor 13-HODE and 12-HETE levels.

  7. IGF-1 (show IGF1 Antibodies) reduces lipid oxidation and foam cell formation via downregulation of 12/15-LOX to prevent atherosclerosis.

  8. enzymatic activity and the intracellular membrane-binding function of 15-LO1 appear to contribute to HIF-1alpha (show HIF1A Antibodies) suppression

  9. These findings demonstrate that 15-LOX-1 expression loss in cancer cells promotes metastasis and that therapeutically targeting ubiquitous 15-LOX-1 loss in cancer cells has the potential to suppress metastasis.

  10. Loss of Alox15 altered expression of PTEN (show PTEN Antibodies), PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies), and the transcription factor ICSBP (show IRF8 Antibodies)

Rabbit Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. Results indicate 15-lipoxygenase modified LDL as a new inducer for LOX-1 (show OLR1 Antibodies) expression and as a new ligand for LOX-1 (show OLR1 Antibodies).

Mouse (Murine) Arachidonate 15-Lipoxygenase (ALOX15) interaction partners

  1. In experimental postoperative ileus, 12/15-lipoxygenase was expressed, mainly in CX3CR1 (show CX3CR1 Antibodies)(+)/Ly6C(+) infiltrating monocytes, not Ly6G(+) neutrophils. 12/15-LOX mediates ileus resolution by producing proresolving docosahexaenoic acid-derived protectin (show CD59 Antibodies) DX.

  2. we show that oxidized phospholipids generated by 12/15-LOX can act as substrates for key proteins required for effective autophagy and that cells deficient in this enzyme show evidence of autophagic dysfunction

  3. SHH (show SHH Antibodies)-responsive 5-lipoxygenase (show ALOX5 Antibodies), 15-lipoxygenase and COX-2 (show COX2 Antibodies) modulate Dectin-1 (show CLEC7A Antibodies)-induced inflammatory cytokines.

  4. Effect of 12/15-LOX on colorectal tumorigenesis in mouse models could be affected by tumor cell type (human or mouse), relative 12/15 LOX activity in tumor cells and stroma as well as the relative tumor 13-HODE and 12-HETE levels.

  5. These observations provide novel insights on the role of XO in 12/15-LO-induced JamA (show F11R Antibodies) tyrosine phosphorylation and TJ disruption leading to increased vascular permeability in response to HFD.

  6. IGF-1 (show IGF1 Antibodies) reduces lipid oxidation and foam cell formation via downregulation of 12/15-LOX to prevent atherosclerosis.

  7. Inactivation of the Alox15 gene does not rescue homozygous knock-in mice expressing catalytically silent Gpx4 (show GPX4 Antibodies).

  8. Data indicate that interleukin-6 (IL-6 (show IL6 Antibodies))/signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies)) signaling pathway.

  9. 12/15-LO determined the DC activation threshold by generating phospholipid oxidation products and a NRF2 (show NFE2L2 Antibodies)-dependent antioxidative response. Deletion or inhibition accelerated maturation and shifted the cytokine profile to favor TH17 cell differentiation.

  10. This study demonstrated that lipoxygenases act cell autonomously within neurons to regulate degeneration, and are required for mitochondrial permeabilization and caspase (show CASP3 Antibodies) activation in the axon

Arachidonate 15-Lipoxygenase (ALOX15) Antigen Profile

Protein Summary

demonstrates 12-lipoxygenase and some 15-lipoxygenase enzyme activity

Gene names and symbols associated with ALOX15

  • arachidonate 15-lipoxygenase (ALOX15) antibody
  • arachidonate 15-lipoxygenase (Nmul_A0532) antibody
  • arachidonate 15-lipoxygenase (Sden_1680) antibody
  • arachidonate 15-lipoxygenase (Swoo_2919) antibody
  • Arachidonate 15-lipoxygenase (PCC8801_3106) antibody
  • Arachidonate 15-lipoxygenase (Cyan8802_3014) antibody
  • Arachidonate 15-lipoxygenase (Nwat_1315) antibody
  • arachidonate 12-lipoxygenase (ALOX12) antibody
  • arachidonate 15-lipoxygenase (Alox15) antibody
  • 12-LO antibody
  • 12-LOX antibody
  • 15-LOX antibody
  • 15-LOX-1 antibody
  • 15LOX-1 antibody
  • Alox12 antibody
  • Alox12l antibody
  • ALOX15 antibody
  • L-12LO antibody

Protein level used designations for ALOX15

arachidonate 15-lipoxygenase , Arachidonate 15-lipoxygenase , 12S-LOX , 12S-lipoxygenase , arachidonate 12-lipoxygenase, 12S-type , 15-LOX , 15-lipooxygenase-1 , arachidonate omega-6 lipoxygenase , 12-LOX , erythroid cell-specific 15-lipoxygenase , lipoxygenase , omega-6 lipoxygenase , arachidonate 12-lipoxygenase, leukocyte-type , 12/15-LOX

GENE ID SPECIES
748294 Pan troglodytes
3784521 Nitrosospira multiformis ATCC 25196
4018156 Shewanella denitrificans OS217
6117234 Shewanella woodyi ATCC 51908
7102416 Cyanothece sp. PCC 8801
8392342 Cyanothece sp. PCC 8802
9392786 Nitrosococcus watsonii C-113
396971 Sus scrofa
246 Homo sapiens
489458 Canis lupus familiaris
282139 Bos taurus
100009114 Oryctolagus cuniculus
11687 Mus musculus
81639 Rattus norvegicus
100174413 Pongo abelii
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