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anti-Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Antibodies

ALOX5AP encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Additionally we are shipping ALOX5AP Kits (10) and ALOX5AP Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX5AP 11690 P30355
ALOX5AP 29624 P20291
ALOX5AP 241 P20292
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Top anti-ALOX5AP Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185717 (0.1µg/ml) staining of Human U937 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Mouse Mouse Un-conjugated WB Western blot analysis of FLAP on a RSV-3T3 cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-FLAP antibody. 50 μg Log in to see 5 to 6 Days
$220.08
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ALOX5AP Antibody (Center) (ABIN392385) in K562 cell line lysates (35 µg/lane). ALOX5AP(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, IHC (p) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$500.50
Details

ALOX5AP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)


Human , ,
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Top referenced anti-ALOX5AP Antibodies

  1. Human Polyclonal ALOX5AP Primary Antibody for EIA, IHC (p) - ABIN360268 : Zintzaras, Rodopoulou, Sakellaridis: Variants of the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene and risk of stroke: a HuGE gene-disease association review and meta-analysis. in American journal of epidemiology 2009 (PubMed)
    Show all 3 references for ABIN360268

  2. Human Polyclonal ALOX5AP Primary Antibody for WB - ABIN265257 : Helgadottir, Manolescu, Thorleifsson, Gretarsdottir, Jonsdottir, Thorsteinsdottir, Samani, Gudmundsson, Grant, Thorgeirsson, Sveinbjornsdottir, Valdimarsson, Matthiasson, Johannsson, Gudmundsdottir et al.: The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. ... in Nature genetics 2004 (PubMed)
    Show all 2 references for ABIN265257

  3. Human Polyclonal ALOX5AP Primary Antibody for IHC, ELISA - ABIN185717 : Kaaman, Rydén, Axelsson, Nordström, Sicard, Bouloumié, Langin, Arner, Dahlman: ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance. in International journal of obesity (2005) 2006 (PubMed)

  4. Human Polyclonal ALOX5AP Primary Antibody for EIA, IHC (p) - ABIN374441 : Maier, Tausch, Hoernig, Coste, Schmidt, Angioni, Metzner, Groesch, Pergola, Steinhilber, Werz, Geisslinger: Celecoxib inhibits 5-lipoxygenase. in Biochemical pharmacology 2008 (PubMed)

  5. Mouse (Murine) Monoclonal ALOX5AP Primary Antibody for WB - ABIN968396 : Liu, Yin: Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies. in The Journal of biological chemistry 1998 (PubMed)

More Antibodies against ALOX5AP Interaction Partners

Mouse (Murine) Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. BRP (show GDF5 Antibodies)-7 potently suppresses leukotriene biosynthesis by interacting with FLAP in mouse peritonitis model.

  2. FLAP regulates phosphorylation of tau protein via modulating GSK-3beta (show GSK3b Antibodies) activity.

  3. This study demonistrated that a a novel role for FLAP in the pathogenesis of anxiety-like behavior in mice.

  4. Deletion of myeloid cell FLAP markedly attenuates the proliferative response to vascular injury, while preserving endothelial integrity.

  5. A FLAP inhibitor given during critical window periods may prevent oxygen induced aberration of pulmonary alveolarization in a dose- and time-dependent manner.

  6. the 5-LO (show ALOX5 Antibodies) pathway emerges early during embryonic stem cell differentiation into cells of the myeloid lineage

  7. Adipose tissue from obese mice, compared with that from lean mice, exhibited increased 5-LO (show ALOX5 Antibodies) activating protein

  8. Data show that 5-lipoxygenase (show ALOX5 Antibodies) activity increases during senescence-like growth arrest via a p53 (show TP53 Antibodies)/p21 (show D4S234E Antibodies)-dependent pathway in both human and mouse embryo fibroblasts.

  9. Altered 5-lipoxygenase (show ALOX5 Antibodies) is associated with obesity and bone traits

  10. This observation supports the hypothesis that 5-LO (show ALOX5 Antibodies) may be involved in diseases of the brain associated with aging.

Human Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. Genetic interaction of CD80 (show CD80 Antibodies) and ALOX5AP was observed in systemic lupus erythematosus in Asian populations.

  2. findings show that several enzymes known to be involved in the biosynthesis of proinflammatory LTs, such as FLAP and cPLA2alpha (show PLA2G4A Antibodies), also contribute to LX and Rv formation

  3. The results of this study supported the association of the epistatic interactions of ALOX5AP, THBD (show THBD Antibodies), and KNG1 (show KNG1 Antibodies) and present novel evidence for the main effect of KNG1 (show KNG1 Antibodies) gene on IS susceptibility

  4. results of the meta-analysis indicate that ALOX5AP rs10507391/SG13S114 A>T polymorphism is not associated with the risk of cerebral infarction in the Chinese population.

  5. Genetic polymorphisms of ALOX5AP and CYP3A5 (show CYP3A5 Antibodies) increase susceptibility to ischemic stroke and are associated with atherothrombotic events in stroke patients.

  6. Our study provides evidence that the promoter single nucleotide polymorphism (SNP) rs17222919 of the ALOX5AP is a potential genetic protective factor for IS in the Chinese Han population.

  7. Report no association between ALOX5AP SNPs and atherosclerotic plaque phenotypes.

  8. THE 5-LOX (show ALOX5 Antibodies) interface involving the four cysteines 159, 300, 416 and 418 is important for the translocation to the nuclear membrane and the colocalization with FLAP.

  9. FLAP protein inhibition attenuates inflammation induced by lipopolysaccharides (LPS (show IRF6 Antibodies)) or the lipid A fraction of LPS (show IRF6 Antibodies).

  10. Rs10507391, rs4769874 and its haplotypes in ALOX5AP are unrelated to ACS (show PLA2G15 Antibodies) risk in the Chinese Han population of Changwu, but elevated serum LTB4 (show PTGR1 Antibodies) level is strongly associated withacute coronary syndrome risk

Cow (Bovine) Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) interaction partners

  1. ALOX5AP, CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.

ALOX5AP Antigen Profile

Protein Summary

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with ALOX5AP

  • arachidonate 5-lipoxygenase-activating protein (alox5ap) antibody
  • arachidonate 5-lipoxygenase-activating protein (ALOX5AP) antibody
  • Arachidonate 5-lipoxygenase-activating protein (al5ap) antibody
  • Arachidonate 5-lipoxygenase-activating protein (flap) antibody
  • 5-lipoxygenase-activating protein (FLAP) antibody
  • arachidonate 5-lipoxygenase activating protein (Alox5ap) antibody
  • al5ap antibody
  • ALOX5AP antibody
  • fj65d02 antibody
  • FLAP antibody
  • wu:fj65d02 antibody
  • zgc:63982 antibody

Protein level used designations for ALOX5AP

arachidonate 5-lipoxygenase-activating protein , Arachidonate 5-lipoxygenase-activating protein , MK-886-binding protein , arachidonate 5 lipoxygenase activating protein , 5-lipoxygenase-activating protein FLAP , FLAP , arachidonate 5-lipoxygenase activating protein , 5-lipoxygenase-activating protein

GENE ID SPECIES
337376 Danio rerio
452520 Pan troglodytes
477323 Canis lupus familiaris
613083 Xenopus (Silurana) tropicalis
770904 Gallus gallus
100286557 Salmo salar
100305320 Oncorhynchus mykiss
100009413 Oryctolagus cuniculus
443326 Ovis aries
11690 Mus musculus
29624 Rattus norvegicus
241 Homo sapiens
613869 Bos taurus
100034178 Equus caballus
397392 Sus scrofa
713170 Macaca mulatta
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