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anti-Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1) Antibodies

Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Additionally we are shipping Aryl Hydrocarbon Receptor Interacting Protein-Like 1 Proteins (11) and Aryl Hydrocarbon Receptor Interacting Protein-Like 1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AIPL1 23746 Q9NZN9
AIPL1 114230 Q924K1
AIPL1 59110 Q9JLG9
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Top anti-Aryl Hydrocarbon Receptor Interacting Protein-Like 1 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB Western Blot analysis of AIPL1 expression in transfected 293T cell line by AIPL1 monoclonal antibody (M04), clone 1E1. Lane 1: AIPL1 transfected lysate(43.9 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC204079 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-AIPL1 antibody (ABIN2455043), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AIPL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-AIPL1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-AIPL1 mouse monoclonal antibody (ABIN2455131) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AIPL1 (RC204079). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AIPL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-AIPL1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC204079 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-AIPL1 antibody (ABIN2455133), and then analyzed by flow cytometry. Anti-AIPL1 mouse monoclonal antibody (ABIN2455133) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AIPL1 (RC204079). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of Aipl1 in human brain tissue lysate with Aipl1 antibody at (A) 1 and (B) 2 µg/ml 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of Aipl1 in human brain tissue with Aipl1 antibody at 2.5 μg/ml. Western blot analysis of Aipl1 in rat brain tissue lysate with AP30037PU-N Aipl1 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of Aipl1 in human brain tissue with Aipl1 antibody at 2.5 μg/ml. Western blot analysis of Aipl1 in human brain tissue lysate with AP30036PU-N Aipl1 antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Ganglion cells: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

AIPL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Aryl Hydrocarbon Receptor Interacting Protein-Like 1 Antibodies

  1. Human Monoclonal AIPL1 Primary Antibody for WB - ABIN394451 : Kirschman, Kolandaivelu, Frederick, Dang, Goldberg, Baehr, Ramamurthy: The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells. in Human molecular genetics 2010 (PubMed)
    Show all 5 references for ABIN394451

More Antibodies against Aryl Hydrocarbon Receptor Interacting Protein-Like 1 Interaction Partners

Human Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1) interaction partners

  1. Findings suggest that AIPL1 function in retinal photoreceptor cells is not related to the role of EB proteins in microtubule dynamics or primary ciliogenesis, but their association may be related to a specific role in the retinal photoreceptors.

  2. The authors established a transgenic mouse model for cone-rod dystrophy carrying human AIPL1 gene with deletion in the C-terminal proline-rich region.

  3. Gene therapy based approach may be worthy of consideration in a small group of selected patients with preserved outer retinal structure in AIPL1 Leber's congenital amaurosis.

  4. Mutations in the AIPL1 and RDH12 (show RDH12 Antibodies) genes associated with leber congenital amaurosis in two Turkish families.

  5. In this chapter, using results obtained from multiple lines of animal models, we discuss the role for AIPL1 in photoreceptors.

  6. The unique proline-rich domain of AIPL1 is important for its chaperone function as its truncation severely affects the ability of AIPL1 to bind non-native proteins.

  7. implicate FAT10 (show UBD Antibodies) in retinal cell biology and Leber congenital amaurosis pathogenesis, and reveal a new role of AIPL1 in regulating the FAT10 (show UBD Antibodies) pathway.

  8. Patients with mutations in AIPL1 may present with Leber congenital amaurosis and residual ERGs (electroretinography) characterized by slow insensitive scotopic responses.

  9. AIPL1-Leber congenital amaurosis (LCA (show CLTA Antibodies)), unlike some other forms of LCA (show CLTA Antibodies) with equally severe visual disturbance, shows profound loss of foveal as well as extrafoveal photoreceptors.

  10. AIPL1 is needed for the proper functioning and survival of cone photoreceptors.

Mouse (Murine) Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1) interaction partners

  1. mechanistic differences behind the death of rods and cones in retinal degenerative disease caused by deficiencies in AIPL1.

  2. In this chapter, using results obtained from multiple lines of animal models, we discuss the role for AIPL1 in photoreceptors.

  3. The binding of PDE6A (show PDE6A Antibodies) farnesyl is essential to normal function of AIPL1 and its disruption is one of the mechanisms underlying Leber congenital amaurosis.

  4. Loss of AIPL1 would result in a condition that phenocopies retinal degenerations in the rd mouse and in a subgroup of human

  5. AIPL1 enhances the stability of phosphodiesterase and is essential for photoreceptor viability.

  6. AIPL1 has a role in the retina and in mouse models of Leber congenital amaurosis [review]

  7. AIPL1 interacts with the catalytic subunit (alpha) of PDE6 and is needed for the assembly of functional rod PDE6 subunits.

Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1) Antigen Profile

Protein Summary

Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA.

Gene names and symbols associated with AIPL1

  • aryl hydrocarbon receptor interacting protein-like 1 (AIPL1) antibody
  • aryl hydrocarbon receptor interacting protein-like 1 (aipl1) antibody
  • aryl hydrocarbon receptor interacting protein-like 1 (LOC100347082) antibody
  • aryl hydrocarbon receptor-interacting protein-like 1 (Aipl1) antibody
  • A930007I01Rik antibody
  • AIPL1 antibody
  • AIPL2 antibody
  • LCA4 antibody

Protein level used designations for AIPL1

aryl hydrocarbon receptor interacting protein-like 1 , aryl-hydrocarbon-interacting protein-like 1 , aryl-hydrocarbon interacting protein-like 1

GENE ID SPECIES
468171 Pan troglodytes
769785 Gallus gallus
100101778 Xenopus (Silurana) tropicalis
100347082 Oryctolagus cuniculus
23746 Homo sapiens
281609 Bos taurus
489447 Canis lupus familiaris
574331 Macaca mulatta
100970167 Pan paniscus
100524458 Sus scrofa
114230 Mus musculus
59110 Rattus norvegicus
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