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anti-Aspartate beta-Hydroxylase (ASPH) Antibodies

ASPH is thought to play an important role in calcium homeostasis. Additionally we are shipping Aspartate beta Hydroxylase Proteins (19) and Aspartate beta Hydroxylase Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASPH 444 Q12797
ASPH 65973 Q8BSY0
ASPH 312981  
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Top anti-Aspartate beta Hydroxylase Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-ASPH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: ACHN cell lysate Immunohistochemistry with Small intestine, myenteric plexus tissue at an antibody concentration of 5µg/ml using anti-ASPH antibody (ARP34691_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ASPH Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB ASPH Antibody (Center)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ASPH antibody detected the ASPH protein (arrow). ASPH Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ASPH Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ASPH Antibody Titration: 5.0ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-ASPH  Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-ASPH Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ASPH Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ASPH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. ASPH Antibody (Center) western blot analysis in A549 cell line lysates (35µg/lane).This demonstrates the ASPH antibody detected the ASPH protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ASPH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- ASPH Picoband antibody,IHC(P) IHC(P): Human Mammary Cancer Tissue Anti- ASPH Picoband antibody, Western blotting All lanes: Anti ASPH  at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Rat Liver Tissue Lysate at 50ug Lane 3: HELA Whole Cell Lysate at 40ug Lane 4: HEPG2 Whole Cell Lysate at 40ug Lane 5: HEPA Whole Cell Lysate at 40ug Predicted bind size: 86KD Observed bind size: 100KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

ASPH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,


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Top referenced anti-Aspartate beta Hydroxylase Antibodies

  1. Human Polyclonal Aspartate beta Hydroxylase Primary Antibody for EIA, IHC (p) - ABIN950540 : Xue, Xue, Huang, Wei, Sun, Xue: Monoclonal antibodies against human aspartyl (asparaginyl) beta-hydroxylase developed by DNA immunization. in Hybridoma (2005) 2009 (PubMed)
    Show all 3 references for ABIN950540

  2. Dog (Canine) Polyclonal Aspartate beta Hydroxylase Primary Antibody for IHC, WB - ABIN2784533 : Xian, Zhang, Cong, Yan, Wang, Wu: Expression of aspartyl beta-hydroxylase and its clinicopathological significance in hepatocellular carcinoma. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006 (PubMed)

  3. Human Polyclonal Aspartate beta Hydroxylase Primary Antibody for WB - ABIN2780587 : Lee: Overexpression of humbug promotes malignant progression in human gastric cancer cells. in Oncology reports 2008 (PubMed)

  4. Human Polyclonal Aspartate beta Hydroxylase Primary Antibody for IHC (p), WB - ABIN656707 : Treves, Franzini-Armstrong, Moccagatta, Arnoult, Grasso, Schrum, Ducreux, Zhu, Mikoshiba, Girard, Smida-Rezgui, Ronjat, Zorzato: Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. in The Journal of cell biology 2004 (PubMed)

More Antibodies against Aspartate beta Hydroxylase Interaction Partners

Human Aspartate beta-Hydroxylase (ASPH) interaction partners

  1. Higher levels of HAAH/humbug mRNA were found in the hepatocellular carcinoma tissues relative to the adjacent cancerfree tissue.

  2. this study provides evidence that ASPH is mutated in a distinct form of syndromic ectopia lentis.

  3. Data show that junctate (ASPH) is an interacting partner of Orai1 (show ORAI1 Antibodies)-STIM1 (show STIM1 Antibodies) complex.

  4. Ca(2 (show CA2 Antibodies)+) and JNT-dependent disassembly of the CSQ2 polymer

  5. Aspartyl-asparaginyl-beta-hydroxylase is an important, positive regulator of trophoblastic cell motility, and it's inhibition in vivo leads to impaired implantation and fetal growth, and alters Notch (show NOTCH1 Antibodies)-signaling mechanisms.

  6. Low expression of AAH in the endochylema and nucleus of trephocyte may play a role in patients with missed abortion.

  7. role of gene in neuroblastoma (show ARHGEF16 Antibodies) cell motility

  8. AAH over-expression may contribute to the infiltrative growth pattern of cholangiocarcinoma cells by promoting motility.

  9. junctate has a role in calcium homeostasis in eukaryotic cells

  10. This review summarizes recent progress in elucidating the molecular mechanisms of hypoxia-inducible factor (HIF)-1 (show HIF1A Antibodies) activation, focusing on the role of oxygen-dependent prolyl hydroxylase in hypoxia signal transduction.

Mouse (Murine) Aspartate beta-Hydroxylase (ASPH) interaction partners

  1. Results predict that junctin ablation, or mutations that alter its structural attributes, may mimic the etiology of catecholaminergic polymorphic ventricular tachycardia by causing enhanced diastolic Ca2 (show CA2 Antibodies)+ leak in the presence of beta-adrenergic activation.

  2. in skeletal muscle the disruption of Tdn (show TRDN Antibodies)/CASQ (show CASQ1 Antibodies) link has a more profound effect on jSR architecture and myoplasmic Ca(2 (show CA2 Antibodies)+) regulation than Jct/CASQ (show CASQ1 Antibodies) association.

  3. Ca(2 (show CA2 Antibodies)+) and JNT-dependent disassembly of the CSQ2 polymer

  4. junctate may play an important role in the regulation of sarcoplasmic reticulum Ca(2 (show CA2 Antibodies)+) cycling through the interaction with SERCA2a (show ATP2A2 Antibodies) in the murine heart.

  5. Cardiac remodeling and atrial fibrillation in transgenic mice overexpressing junctin

  6. the N-terminus of junctate interacts with the C-terminus of TRPC2 (show TRPC2 Antibodies)

  7. To gain more insight into the underlying mechanisms of impaired contractile relaxation in transgenic mice with cardiac-specific overexpression of junctin (TG), we studied cellular Ca(2 (show CA2 Antibodies)+) handling in these mice.

  8. Junctin is an essential regulator of sarcoplasmic reticulum Ca release and contractility in normal hearts. Ablation of junctin is associated with aberrant Ca homeostasis, which leads to fatal arrhythmias

  9. Data suggest that junctate over-expression is associated with an increase in the sarcoplasmic reticulum Ca2 (show CA2 Antibodies)+ storage capacity and releasable Ca2 (show CA2 Antibodies)+ content and support a physiological role for junctate in intracellular Ca2 (show CA2 Antibodies)+ homeostasis.

  10. review of recent findings concerning the expressional regulations and the proposed functions of junctin and junctate

Aspartate beta Hydroxylase (ASPH) Antigen Profile

Protein Summary

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

Gene names and symbols associated with ASPH

  • aspartate beta-hydroxylase (asph) antibody
  • similar to Aspartyl/asparaginyl beta-hydroxylase (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) (LOC559236) antibody
  • aspartate beta-hydroxylase (ASPH) antibody
  • aspartate-beta-hydroxylase (Asph) antibody
  • 2310005F16Rik antibody
  • 3110001L23Rik antibody
  • AAH antibody
  • AI848629 antibody
  • AW261690 antibody
  • AW561901 antibody
  • BAH antibody
  • C79816 antibody
  • CASQ2BP1 antibody
  • cb971 antibody
  • cI-37 antibody
  • fb69e10 antibody
  • fc06d04 antibody
  • fc95a08 antibody
  • HAAH antibody
  • JCTN antibody
  • junctin antibody
  • MGC107896 antibody
  • wu:fb69e10 antibody
  • wu:fc06d04 antibody
  • wu:fc95a08 antibody

Protein level used designations for ASPH

aspartate beta-hydroxylase , similar to Aspartyl/asparaginyl beta-hydroxylase (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) , junctin , A beta H-J-J , ASP beta-hydroxylase , aspartyl/asparaginyl beta-hydroxylase , aspartyl/asparaginyl-beta-hydroxylase , cardiac junctin , humbug , junctate , peptide-aspartate beta-dioxygenase , junctional sarcoplasmic reticulum protein , aspartyl beta-hydroxylase , calsequestrin-binding protein , jumbug

GENE ID SPECIES
548451 Xenopus (Silurana) tropicalis
559236 Danio rerio
100137711 Xenopus laevis
323659 Danio rerio
100581524 Nomascus leucogenys
421142 Gallus gallus
444 Homo sapiens
286771 Bos taurus
403846 Canis lupus familiaris
65973 Mus musculus
312981 Rattus norvegicus
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