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Ataxin 1 (ATXN1) ELISA Kits

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Additionally we are shipping Ataxin 1 Antibodies (197) and Ataxin 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ATXN1 6310 P54253
ATXN1 20238 P54254
ATXN1 25049 Q63540
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Top Ataxin 1 ELISA Kits at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.19 ng/mL 0.31-20 ng/mL Diagramm of the ELISA kit to detect Human ATXN1with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$680.63
Details
Rat 0.19 ng/mL 0.31-20 ng/mL Diagramm of the ELISA kit to detect Rat ATXN1with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$680.63
Details
Mouse 9.38 pg/mL 15.63-1000 pg/mL Diagramm of the ELISA kit to detect Mouse ATXN1with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Log in to see 8 to 9 Days
$680.63
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
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Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
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Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Guinea Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
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Goat
  96 Tests Log in to see 11 to 13 Days
$801.43
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Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
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More ELISA Kits for Ataxin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ataxin 1 (ATXN1) interaction partners

  1. Ataxin-1 induces intranuclear accumulation of dAtx2/hAtaxin-2 in both Drosophila and SCA1 postmortem neurons

  2. mutant ataxin-1 and huntingtin (show HTT ELISA Kits) induce developmental and late-onset neuronal pathologies in Drosophila models

Human Ataxin 1 (ATXN1) interaction partners

  1. This study reports the results of molecular dynamics simulations of AXH monomer of Ataxin-1.

  2. Systematic replacement of each lysine residue in the AXH domain revealed that the lysine at 589 (K589) of ATXN1 is essential for its ubiquitylation by UbcH6 (show UBE2E1 ELISA Kits).

  3. Results show that two SNPs in ATXN1 gene have a founder effect of the same repeat carrying allele as in the general Indian population suggesting that that Spinocerebellar ataxia (show USP14 ELISA Kits) type 1 disease onset is significantly delayed when transmission is maternal.

  4. this work provides the structural and molecular basis of the interaction between RBM17 (show RBM17 ELISA Kits) and the phosphorylated form of ATXN1.

  5. Partner recognition of the AXH domain of the transcriptional co-regulator ataxin-1 is fine-tuned by a subtle balance between self- and hetero-associations.

  6. We measured cerebellar neurochemical alterations in a knock-in mouse model of spinocerebellar ataxia (show USP14 ELISA Kits) type 1, a hereditary movement disorder, using ultra-high field magnetic resonance spectroscopy (MRS).

  7. Data indicate that the alternative ataxin-1 (ATXN1) protein is constitutively co-expressed and interacts with ATXN1.

  8. SCA 1 was the most frequent occurring type of SCA identified in the Autosomal dominant hereditary ataxia (show USP14 ELISA Kits) in Sri (show SRI ELISA Kits) Lanka.

  9. Results show variation in ATXN1 is implicated in disordered gambling

  10. conformational heterogeneity of the AXH domain of ataxin-1

Mouse (Murine) Ataxin 1 (ATXN1) interaction partners

  1. The results of this study found that upregulation of cholecystokinin (Cck (show CCK ELISA Kits)) and subsequent interaction with the Cck1 (show CCL28 ELISA Kits) receptor likely underlies the lack of progressive Purkinje cell pathology in Pcp2-ATXN1[30Q]D776 mice.

  2. Mutant ATXN1 forms oligomers whose levels correlate with disease progression in the Atxn1154Q/+ mice.

  3. The study showed that Sca1(+)Lin(-) bone marrow contains an endodermal precursor population of cells that differentiates into hepatocytes.

  4. HMGB1 (show HMGB1 ELISA Kits) facilitates repair of mitochondrial DNA damage of mutant ataxin-1 knock-in mice.

  5. The RNA-binding protein PUMILIO1 (PUM1 (show PUM1 ELISA Kits)) not only directly regulates ATAXIN1 but also plays an unexpectedly important role in neuronal function. Loss of Pum1 (show PUM1 ELISA Kits) caused progressive motor dysfunction and SCA1-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 levels.

  6. study found a new function of ataxin-1: the modulation of Pp2a activity and the regulation of its holoenzyme composition, with the polyglutamine mutation within Atxn1 altering this function in the spinocerebellar ataxia (show USP14 ELISA Kits) type 1 mouse cerebellum before disease onset

  7. Delivery of either ataxin-1-like viral vectors to Spinocerebellar Ataxia (show USP14 ELISA Kits) Type 1 mice cerebella resulted in widespread cerebellar Purkinje cell transduction

  8. downregulation of several components of the RAS-MAPK (show MAPK1 ELISA Kits)-MSK1 (show RPS6KA5 ELISA Kits) pathway decreases ATXN1 levels and suppresses neurodegeneration in mice

  9. we show that ATXN1 reduces histone acetylation, a post-translational modification of histones associated with enhanced transcription, and represses histone acetyl transferase (show HAT1 ELISA Kits)-mediated transcription.

  10. Loss of ATXN1, Atxn1L and CIC (show CIC ELISA Kits) is associated with hydrocephalus, omphalocele, and lung alveolarization defects.

Ataxin 1 (ATXN1) Antigen Profile

Antigen Summary

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with Ataxin 1 (ATXN1) ELISA Kits

  • ataxin 1 (ATXN1) antibody
  • ataxin 1b (atxn1b) antibody
  • Ataxin 1 (Atx-1) antibody
  • ataxin 1 (Atxn1) antibody
  • ataxin 1-like (ATXN1L) antibody
  • 2900016G23Rik antibody
  • ataxin 1b antibody
  • Atx1 antibody
  • atxn1 antibody
  • C85907 antibody
  • CG4547 antibody
  • D6S504E antibody
  • dAtx-1 antibody
  • dAtx1 antibody
  • Dmel\\CG4547 antibody
  • ENSMUSG00000074917 antibody
  • Gm10786 antibody
  • sca1 antibody

Protein level used designations for Ataxin 1 (ATXN1) ELISA Kits

ataxin 1 , spinocerebellar ataxia type 1 , Ataxin1 , Atx-1-PB , CG4547-PB , ataxin-1 , ataxin-1-like , spinocerebellar ataxia type 1 protein , spinocerebellar ataxia 1 homolog , spinocerebellar ataxia 1 , spinocerebellar ataxia type 1 protein homolog , spinocerebellar ataxia type 1 protien

GENE ID SPECIES
100065748 Equus caballus
493678 Felis catus
565841 Danio rerio
747421 Pan troglodytes
31624 Drosophila melanogaster
100025666 Monodelphis domestica
100402564 Callithrix jacchus
100437511 Pongo abelii
100467930 Ailuropoda melanoleuca
100588152 Nomascus leucogenys
6310 Homo sapiens
20238 Mus musculus
25049 Rattus norvegicus
488232 Canis lupus familiaris
100154571 Sus scrofa
616399 Bos taurus
100719683 Cavia porcellus
420843 Gallus gallus
101113284 Ovis aries
489725 Canis lupus familiaris
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