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anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) Antibodies

CLEC7A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC7A Kits (30) and CLEC7A Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLEC7A 56644 Q6QLQ4
CLEC7A 64581 Q9BXN2
CLEC7A 502902  
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Top anti-CLEC7A Antibodies at antibodies-online.com

Showing 10 out of 179 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat FITC FACS Staining of mouse peripheral blood granulocytes with RAT ANTI MOUSE BETA GLUCAN RECEPTOR:FITC (ABIN181894). 0.1 mg Log in to see 6 to 8 Days
$357.50
Details
Mouse Rat Biotin FACS Staining of mouse peripheral blood granulocytes with RAT ANTI MSE BETA GLUCAN RECEPTOR:BIOTIN (ABIN181893). 0.1 mg Log in to see 6 to 8 Days
$709.50
Details
Mouse Rat Un-conjugated FACS, IHC (fro), IP Staining of mouse peripheral blood monocytes with RAT ANTI MOUSE BETA GLUCAN RECEPTOR (ABIN181896). 0.25 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of CLEC7A in human spleen tissue with CLEC7A antibody at 5 µg/ml. Western blot analysis of CLEC7A in rat spleen tissue lysate with CLEC7A antibody at (A) 1 and (B) 2 µg/. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Rat Un-conjugated Func, FACS, IHC (fro), IP Staining of mouse peripheral blood monocytes with RAT ANTI MOUSE BETA GLUCAN RECEPTOR (ABIN181895). 0.5 mg Log in to see 6 to 8 Days
$731.50
Details
Mouse Rat PE FACS   100 Tests Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CLEC7A / Dectin 1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961784 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Colon, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse PE FACS 25 Tests Log in to see 11 to 16 Days
$185.71
Details

CLEC7A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CLEC7A Antibodies

  1. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for Func, FACS - ABIN181895 : Reid, Montoya, Taylor, Borrow, Gordon, Brown, Wong: Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. in Journal of leukocyte biology 2004 (PubMed)
    Show all 7 references for ABIN181895

  2. Human Polyclonal CLEC7A Primary Antibody for EIA, IF - ABIN1449932 : Kerrigan, Brown: Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs. in Immunological reviews 2010 (PubMed)
    Show all 4 references for ABIN1449932

  3. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN320108 : Brown, Taylor, Reid, Willment, Williams, Martinez-Pomares, Wong, Gordon: Dectin-1 is a major beta-glucan receptor on macrophages. in The Journal of experimental medicine 2002 (PubMed)
    Show all 4 references for ABIN320108

  4. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS, IHC (fro) - ABIN181896 : Taylor, Brown, Reid, Willment, Martinez-Pomares, Gordon, Wong: The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for ABIN181896

  5. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN181893 : Underhill, Rossnagle, Lowell, Simmons: Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. in Blood 2005 (PubMed)
    Show all 2 references for ABIN181893

More Antibodies against CLEC7A Interaction Partners

Pig (Porcine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. These results suggest that functionally neutral polymorphisms in dectin-1 are widespread in pig populations

  2. recognition of beta-glucans appeared cell type-specific as both dectin-1 and CR3 (show ITGAM Antibodies) are involved in the beta-glucan-mediated responses in pig macrophages.

Mouse (Murine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. Mast cells are able to phagocytose and produce nitric oxide against Candida albicans via TLR2 (show TLR2 Antibodies)/Dectin-1.

  2. TREM-1 (show TREM1 Antibodies) and Dectin-1 function concurrently in the corneal innate immune response by regulating inflammatory cytokine expression in fungal keratitis.

  3. Sc CW-derived BG stimulated the late and strong expression of Csf2 (show CSF2 Antibodies) in a dectin-1-dependent manner, they remain poor inducers of chemokine (show CCL1 Antibodies) and cytokine production in murine macrophages.

  4. recognition of beta-1,3 glucan by Dectin-1 triggers TLR9 (show TLR9 Antibodies) trafficking to beta-1,3 glucan-containing phagosomes, which may be critical in coordinating innate antifungal defense.

  5. These observations suggest that Dectin-1 regulates the homeostasis of intestinal immunity by controlling Treg cell differentiation through modification of microbiota.

  6. our findings define the mechanism of receptor crosstalk between CR3 (show ITGAM Antibodies) and Dectin-1 and demonstrate the importance of their collaboration in host defense against fungal infection.

  7. Findings indicate a role for inositol-polyphosphate 5-phosphatase SHIP-1 coupling to DC-type lectin receptor ectin-1 hemITAM in the selective control of downstream responses.

  8. Dectin-1 Activation by a Natural Product beta-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype.

  9. SHH (show SHH Antibodies)-responsive 5-lipoxygenase (show ALOX5 Antibodies), 15-lipoxygenase and COX-2 (show COX2 Antibodies) modulate Dectin-1-induced inflammatory cytokines.

  10. dectin-1 plays a critical role in the ability of complete Freund's adjuvant to induce experimental autoimmune uveoretinitis in mice.

Human C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. study represents the first analysis demonstrating that harbouring polymorphisms of Dectin-1 (rs7309123) or TLR2 (show TLR2 Antibodies) (rs5743708) represents an independent risk factor of developing IFD in patients with AML (show RUNX1 Antibodies) undergoing induction chemotherapy.

  2. TREM-1 (show TREM1 Antibodies) and Dectin-1 function concurrently in the corneal innate immune response by regulating inflammatory cytokine expression in fungal keratitis.

  3. Our data suggest that the genetic diversity of CLEC7A gene influences the autism spectrum disorders (ASD (show ARSD Antibodies)) phenotype by behaving as a disease specifier and imply that the genetic control of innate immune response could determine the ASD (show ARSD Antibodies) phenotype.

  4. The result of this study suggests that there is no correlation between Dectin-1 Y238X Gene polymorphism and RVVC.

  5. This study demonstrated that Toll (show TLR4 Antibodies)-Like Receptors and Dectin-1, a C-Type Lectin Receptor (show CLEC4D Antibodies), Trigger Divergent Functions in CNS Macrophages.

  6. Data indicate that Candida albicans beta-Glucan induces high IL-1 (show IL1A Antibodies) receptor antagonist (IL-1Ra (show IL1RN Antibodies)) levels, independently from Dectin-1/complement receptor 3 (CR3 (show ITGAM Antibodies)).

  7. The analysis of Dectin-1 gene polymorphisms showed no significant association with fungal keratitis in the northern Han Chinese population.

  8. Dectin-1 expressed on human pulmonary epithelial cells has a considerable impact on the Nontypeable Haemophilus influenzae triggered immune response.

  9. The superoxide induction with whole glucan particle was concluded to be Dectin-1-mediated and required Src (show SRC Antibodies) family kinases, phosphatidylinositol-3 kinase and protein kinase B/Akt (show AKT1 Antibodies).

  10. CARD9 (show CARD9 Antibodies) regulates H-Ras (show HRAS Antibodies) activation by linking Ras-GRF1 (show RASGRF1 Antibodies) to H-Ras (show HRAS Antibodies), which mediates Dectin-1-induced extracellular signal-regulated protein kinase (show CDK7 Antibodies) (ERK (show EPHB2 Antibodies)) activation and proinflammatory responses when stimulated by their ligands.

Cow (Bovine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. CLEC7a genetic variant c.589A>G was significantly associated (p = 0.008) with Mycobacterium avium ssp. paratuberculosis infection in Holsteins cattle.

CLEC7A Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC7A

  • C-type lectin domain family 7, member A (CLEC7A) antibody
  • C-type lectin domain family 7, member a (Clec7a) antibody
  • C-type lectin domain family 7, member A (Clec7a) antibody
  • dendritic cell-associated C-type lectin 1 (LOC100339146) antibody
  • beta-GR antibody
  • BGR antibody
  • CANDF4 antibody
  • CLEC7A antibody
  • Clec7b antibody
  • CLECSF12 antibody
  • DECTIN1 antibody
  • RGD1565140 antibody

Protein level used designations for CLEC7A

dendritic cell-associated C-type lectin 1 , C-type lectin domain family 7, member A , C-type lectin domain family 7 member A , dectin 1 , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , C-type lectin superfamily member 12 , DC-associated C-type lectin 1 , beta-glucan receptor , dectin-1 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12 , dendritic cell-associated C-type lectin-1 , lectin-like receptor 1

GENE ID SPECIES
473361 Pan troglodytes
611385 Canis lupus familiaris
678685 Ovis aries
100038025 Sus scrofa
56644 Mus musculus
64581 Homo sapiens
532865 Bos taurus
502902 Rattus norvegicus
574356 Macaca mulatta
100339146 Oryctolagus cuniculus
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