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C1QTNF5 encodes a member of the a member of the C1q/tumor necrosis factor superfamily. Additionally we are shipping C1q and Tumor Necrosis Factor Related Protein 5 Proteins (8) and C1q and Tumor Necrosis Factor Related Protein 5 Kits (6) and many more products for this protein.
Showing 10 out of 83 products:
Human Polyclonal C1QTNF5 Primary Antibody for EIA, IHC (p) - ABIN499673
Fantuzzi: Adipose tissue, adipokines, and inflammation. in The Journal of allergy and clinical immunology 2005
Show all 4 references for ABIN499673
Human Polyclonal C1QTNF5 Primary Antibody for EIA, WB - ABIN499675
Tsao, Lodish, Fruebis: ACRP30, a new hormone controlling fat and glucose metabolism. in European journal of pharmacology 2002
Show all 4 references for ABIN499675
Human Polyclonal C1QTNF5 Primary Antibody for WB - ABIN2473125
Laine: Helicobacter pylori and non-ulcer dyspepsia. in Gastroenterology 1992
Show all 2 references for ABIN2473125
Human Polyclonal C1QTNF5 Primary Antibody for FACS, WB - ABIN4899276
Wong, Krawczyk, Kitidis-Mitrokostas, Revett, Gimeno, Lodish et al.: Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, ... in The Biochemical journal 2008
Sequencing of C1QTNF5 revealed 28 unique variants although none showed a statistically significant association with dt-GA when compared with 1000G individuals.
Our results provide the first genetic and physiological evidence for CTRP5 as a negative regulator of glucose metabolism and insulin (show INS Antibodies) sensitivity. Inhibition of CTRP5 action may result in the alleviation of insulin (show INS Antibodies) resistance associated with obesity and diabetes.
Late-onset retinal degeneration, proven to have the p.Ser163Arg mutation in C1QTNF5, and asked whether retina-wide sub-RPE (show RPE Antibodies) deposit was detectable and quantifiable.
C1QTNF5 monomers can multimerize into a bouquet-like octadecamer.
CTRP-5 might be a novel adipokine that circulates abundantly in human sera.
C1QTNF5 retinopathy is an autosomal dominant LORD resulting in a complex ocular phenotype involving the RPE (show RPE Antibodies) and ciliary epithelium. SD-OCT (show Plxna2 Antibodies) findings revealed widespread photoreceptor loss and diffuse choroidal thinning.
cloning of the bicistronic transcript and characterization of the upstream ORF, MFRP (show MFRP Antibodies)
The crystal structure of the trimeric globular domain of human C1QTNF5 at 1.34A resolution reveals unique features of this novel C1q family member.
pathogenic role of C1qtnf5 Ser163Arg mutation
A physiological function for C1QTNF5 (myonectin) in linking insulin (show INS Antibodies) resistance with quantitative changes in mtDNA.
Presence of rd8 (Crb1 (show CRB1 Antibodies)) mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model carrying the Ctrp5 mutation.
CTRP-5 is functionally involved in adipocyte biology.
Ets-2 (show ETS2 Antibodies) play a key role in transcriptional regulation of CTRP5 in muscle cells.
L-ORMD is due to insufficient levels of secreted C1QTNF5, compromised RPE (show RPE Antibodies) cell function resulting from ER retention of the mutant protein or both mechanisms.
CTRP5, a secretory and membrane-associated protein (show PDZK1IP1 Antibodies), is localized to the lateral and apical membranes of the RPE (show RPE Antibodies) and CB. Impaired secretion of the mutant protein may underlie the pathophysiology of long anterior zonules and late-onset retinal degeneration.
This gene encodes a member of the a member of the C1q/tumor necrosis factor superfamily. The encoded protein may be a component of basement membranes and may play a role in cell adhesion. This gene is contained entirely within the 3' UTR of the membrane frizzled-related protein gene on chromosome 11q23 and both genes are expressed from a bicistronic transcript. Mutations in this gene have been associated with late-onset retinal degeneration.
C1q and tumor necrosis factor related protein 5
, complement C1q tumor necrosis factor-related protein 5
, C1q TNF-alpha-related protein 5