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CD163 Molecule Proteins (CD163)

The protein encoded by CD163 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. Additionally we are shipping CD163 Antibodies (296) and CD163 Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD163 93671 Q2VLH6
Rat CD163 CD163 312701  
CD163 9332 Q86VB7
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Top CD163 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 3 to 4 Days
$190.93
Details
HOST_HEK-293 Cells Human His tag   100 μg Log in to see 2 to 3 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Pig Un-conjugated   10 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

CD163 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , ,
, ,

More Proteins for CD163 Molecule (CD163) Interaction Partners

Mouse (Murine) CD163 Molecule (CD163) interaction partners

  1. During ischaemia, soluble CD163 functions as a decoy receptor for TWEAK (show TNFSF12 Proteins), to regulate TWEAK (show TNFSF12 Proteins)-induced activation of canonical nuclear factor-kappaB and Notch (show NOTCH1 Proteins) signalling necessary for myogenic progenitor cell proliferation.

  2. Data indicate an essential substrate motif for ADAM17 (show ADAM17 Proteins)-mediated CD163 and proTNF-alpha cleavage in macrophages.

  3. alpha(1)-Acid glycoprotein (show ORM1 Proteins) up-regulates CD163 via TLR4 (show TLR4 Proteins)/CD14 protein (show ERGIC2 Proteins) pathway: possible protection against hemolysis-induced oxidative stress.

  4. Data show that telmisartan reduced the mRNA expression of CD11c (show ITGAX Proteins) and TNF-alpha (show TNF Proteins), M1 macrophage markers, and significantly increased the expressions of M2 markers, such as CD163, CD209 (show CD209 Proteins).

  5. Assignment of the CD163 antigen to mouse chromosome 6 band F2.

Human CD163 Molecule (CD163) interaction partners

  1. we have developed a highly sensitive targeted probe capable of detecting CD163-expressing macrophages that could provide useful information about the state of the atheromatous lesions.

  2. A subset of CD163+ macrophages displays mixed polarizations in discoid lupus skin.

  3. Increased soluble CD163 blood levels in hepatocellular carcinoma patients correlates with rapid hepatocellular carcinoma progression.

  4. these data indicate that sCD163 is a prognostic marker in B-CLL.

  5. sCD163 is a sensitive marker protein for liver failure.

  6. CD163-positive macrophages predict outcome in follicular lymphoma, but their prognostic impact is highly dependent on treatment received.

  7. therapy with rituximab, cyclophosphamide and fludarabine resulted in a significant reduction in the number of non-classical CD14 (show NDUFA2 Proteins)+CD16 (show CD16 Proteins)++ monocytes and soluble form of CD163 but upregulation of membrane-associated monocyte CD163

  8. Renal graft CD163+ infiltrates correlated strongly with interstitial inflammation, tubulitis, and peritubular capillaritis.

  9. Higher levels of circulating monocyte-platelet aggregates are correlated with viremia and increased sCD163 levels in HIV-1 infection.

  10. CD-163, related to immune-system (macrophage), correlated with symptoms (pain or discomfort) of prostatic inflammation.

Pig (Porcine) CD163 Molecule (CD163) interaction partners

  1. CD163 represents an additional candidate gene for resistance against porcine reproductive and respiratory syndrome.

  2. Overexpression of ADAM17 (show ADAM17 Proteins) induced downregulation of CD163 expression and a reduction in reproductive and respiratory syndrome virus infection.

  3. Fusion protein of sialoadhesin (show SIGLEC1 Proteins) and domains 5-9 of CD163 receptors blocked the respiratory syndrome virus infection.

  4. GP4 (show CD36 Proteins) is involved in interaction with cellular receptor CD163.

  5. ). These results provided fundamental evidence for CD163 and SN as two functional candidate genes affecting immunity in pigs.

  6. Porcine reproductive and respiratory syndrome virus GP4 (show CD36 Proteins) was found to co-localize with CD163 in the lipid rafts on the plasma membrane.

  7. Our results suggest that the intracellular domain of CD163 may be associated with an important yet-unknown function during porcine reproductive and respiratory syndrome virus replication.

  8. The newly established porcine alveolar macrophage cell lines were demonstrated to express robust levels of CD163 and to be fully permissive for both type 1 and 2 porcine reproductive and respiratory syndrome virus strains.

  9. The carboxy-terminal 223 residues of the CD163 molecule are not required for interactions with either the GP2a or the GP4 (show CD36 Proteins) protein, although these residues are required for conferring susceptibility to PRRSV infection.

  10. CD163 is shown to be involved in PRRSV (porcine reproductive and respiratory syndrome virus) entry, probably during uncoating, and to interact with sialoadhesin (show SIGLEC1 Proteins) in the process.

CD163 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with CD163 Molecule Proteins (CD163)

  • deleted in malignant brain tumors 1 protein-like (LOC426820)
  • CD163 molecule (CD163)
  • CD163 antigen (Cd163)
  • CD163 molecule (Cd163)
  • CD163 protein
  • CD163v2 protein
  • CD163v3 protein
  • DMBT1 protein
  • M130 protein
  • MM130 protein

Protein level used designations for CD163 Molecule Proteins (CD163)

CD163 antigen , CD163 molecule , scavenger receptor cysteine-rich type 1 protein M130-like , scavenger receptor cysteine-rich type 1 protein M130 , hemoglobin scavenger receptor , macrophage-associated antigen , CD163v2 , CD163v3

GENE ID SPECIES
426820 Gallus gallus
451815 Pan troglodytes
100393445 Callithrix jacchus
100605146 Nomascus leucogenys
93671 Mus musculus
312701 Rattus norvegicus
9332 Homo sapiens
397031 Sus scrofa
533844 Bos taurus
477704 Canis lupus familiaris
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