CD163 Protein (CD163) (AA 86-365, partial) (His tag)
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- Target See all CD163 Proteins
- CD163
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 86-365
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Origin
- Mouse
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Source
- Yeast
- Purification tag / Conjugate
- This CD163 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- VVCQQLGCPT SIKALGWANS SAGSGYIWMD KVSCTGNESA LWDCKHDGWG KHNCTHEKDA GVTCSDGSNL EMRLVNSAGH RCLGRVEIKF QGKWGTVCDD NFSKDHASVI CKQLGCGSAI SFSGSAKLGA GSGPIWLDDL ACNGNESALW DCKHRGWGKH NCDHAEDVGV ICLEGADLSL RLVDGVSRCS GRLEVRFQGE WGTVCDDNWD LRDASVVCKQ LGCPTAISAI GRVNASEGSG QIWLDNISCE GHEATLWECK HQEWGKHYCH HREDAGVTCS
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CD163 Protein
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CD163 (CD163) (AA 39-1045) protein (His tag)
CD163 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 42-1045) protein (His-Avi Tag)CD163 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 42-1045) protein (His-Avi Tag,Biotin)CD163 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 78-168) protein (GST tag)CD163 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CD163
- Alternative Name
- C163A (CD163 Products)
- Synonyms
- DMBT1 Protein, CD163 Protein, CD163v2 Protein, CD163v3 Protein, M130 Protein, MM130 Protein, deleted in malignant brain tumors 1 protein-like Protein, CD163 molecule Protein, CD163 antigen Protein, LOC426820 Protein, CD163 Protein, Cd163 Protein
- Background
- Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 .After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
- Molecular Weight
- 32.2 kDa
- UniProt
- Q2VLH6
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