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CD47 Proteins (CD47)

CD47 encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. Additionally we are shipping CD47 Antibodies (276) and CD47 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD47 16423 Q61735
CD47 961 Q08722
CD47 29364 P97829
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Top CD47 Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$308.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Human His tag 10 μg Log in to see 2 to 3 Days
$231.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

CD47 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, ,
Human , , , , , ,
, , , , ,
Rat (Rattus)
,

Top referenced CD47 Proteins

  1. Human CD47 Protein expressed in HEK-293 Cells - ABIN2180804 : Piccio, Vermi, Boles, Fuchs, Strader, Facchetti, Cella, Colonna: Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation. in Blood 2005 (PubMed)
    Show all 3 references for ABIN2180804

More Proteins for CD47 Interaction Partners

Mouse (Murine) CD47 interaction partners

  1. atherogenesis is associated with upregulation of CD47, a key anti-phagocytic molecule that is known to render malignant cells resistant to programmed cell removal, or 'efferocytosis'

  2. Erythrocyte CD47 has a key role in hematoma clearance after intracerebral hemorrhage.

  3. These data indicate that CD47 plays protective roles against disseminated candidiasis and alters pro-inflammatory and immunosuppressive pathways known to regulate innate and T cell immunity.

  4. CD47 deficiency ameliorates lupus nephritis in Fas(lpr (show FAS Proteins)) mice via suppression of IgG autoantibody production.

  5. the cell adhesion molecule (show MCAM Proteins) CD47 participates in multiple phases of granule cell development, including proliferation, migration, and neurite differentiation

  6. CD47 mediates signaling from the extracellular matrix that coordinately regulates basal metabolism and cytoprotective responses to radiation injury

  7. Taken together, these data revealed a novel role for CD47 in the development of obesity and its related metabolic complications.

  8. NF KB mediated CD47 up regulation promotes sorafenib resistance treating hepatocellular carcinoma.

  9. Loss of cell surface CD47 clustering formation and binding avidity to SIRPalpha facilitate apoptotic cell clearance by macrophages.

  10. findings prove that the TSP-1 (show GZMA Proteins)/CD47/SIRP (show SIRPA Proteins)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 (show THBS1 Proteins) as a key signal

Human CD47 interaction partners

  1. Data suggest a reduction in the CD47 antigen/signal-regulatory protein alpha (show SIRPA Proteins) (SIRPalpha) pathway by programmed cell death protein 1 (PD-1 (show PDCD1 Proteins)) blockade, which regulates Myeloid-derived suppressor cells (MDSCs) and tumor associated macrophages (TAMs).

  2. atherogenesis is associated with upregulation of CD47, a key anti-phagocytic molecule that is known to render malignant cells resistant to programmed cell removal, or 'efferocytosis'

  3. CD47 is a critical regulator in the metastasis of osteosarcoma and results suggest that targeted inhibition of this antigen by anti-CD47 may be a novel immunotherapeutic approach in the management of this tumor.

  4. agents that block the CD47:SIRP (show SIRPA Proteins)-alpha engagement are attractive therapeutic targets as a monotherapy or in combination with additional immune-modulating agents for activating antitumor T cells in vivo

  5. CD47 is an adverse prognostic factor and promising therapeutic target in gastric cancer.

  6. study demonstrates that antigen-presenting cells(CD47+) in coculture with human macrophages show a CD47 concentration-dependent inhibition of phagocytosis

  7. CD47 expression contributes to the lethal breast cancer phenotype that is mediated by HIF-1 (show HIF1A Proteins).

  8. CD47 is highly expressed on cancer stem cells, but not on other nonmalignant cells in the pancreas.

  9. CD47 mediates signaling from the extracellular matrix that coordinately regulates basal metabolism and cytoprotective responses to radiation injury

  10. CD47 has a central role in hydrogen sulfate biosynthesis, regulation and signaling in T cells.

Pig (Porcine) CD47 interaction partners

  1. Amyloid-beta inhibits No-cGMP signaling in a CD36 (show CD36 Proteins)- and CD47-dependent manner

  2. Genetic induction of human CD47 on porcine cells could provide inhibitory signaling to SIRPalpha on human macrophages, providing a novel approach to preventing macrophage-mediated xenograft rejection.

CD47 Protein Profile

Protein Summary

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CD47 Proteins (CD47)

  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47)
  • CD47 molecule (CD47)
  • Cd47 molecule (Cd47)
  • 9130415E20Rik protein
  • AA407862 protein
  • AI848868 protein
  • AW108519 protein
  • B430305P08Rik protein
  • CD47/IAP protein
  • IAP protein
  • Itgp protein
  • MER6 protein
  • OA3 protein

Protein level used designations for CD47 Proteins (CD47)

Rh-related antigen , integrin-associated protein , leukocyte surface antigen CD47 , CD47 antigen (Rh-related antigen, integrin-associated signal transducer) , CD47 glycoprotein , antigen identified by monoclonal antibody 1D8 , antigenic surface determinant protein OA3 , integrin associated protein , integrin-associated signal transducer , CD47 antigen , IAP

GENE ID SPECIES
16423 Mus musculus
961 Homo sapiens
478552 Canis lupus familiaris
397042 Sus scrofa
282661 Bos taurus
101111153 Ovis aries
29364 Rattus norvegicus
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