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CNDP Dipeptidase 2 (Metallopeptidase M20 Family) Proteins (CNDP2)

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CNDP2 Antibodies (72) and CNDP2 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNDP2 55748 Q96KP4
CNDP2 66054 Q9D1A2
CNDP2 291394 Q6Q0N1
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Top CNDP2 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Baculovirus infected Insect Cells Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Baculovirus infected Insect Cells Human His tag 10 μg Log in to see 16 Days
$206.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,336.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,336.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,336.67
Details

CNDP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) , ,

Rat (Rattus)

Top referenced CNDP2 Proteins

  1. Human CNDP2 Protein expressed in Escherichia coli (E. coli) - ABIN1098517 : Otani, Okumura, Nagai, Okumura: Colocalization of a carnosine-splitting enzyme, tissue carnosinase (CN2)/cytosolic non-specific dipeptidase 2 (CNDP2), with histidine decarboxylase in the tuberomammillary nucleus of the hypothalamus. in Neuroscience letters 2008 (PubMed)
    Show all 2 references for ABIN1098517

More Proteins for CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) Interaction Partners

Human CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) interaction partners

  1. To identify substrates of orphan transporter ATP-binding cassette subfamily C member 5 (ABCC5 (show ABCC5 Proteins)), identified a class of metabolites, N-lactoyl-amino acids, and found that a protease, cytosolic nonspecific dipeptidase 2 (CNDP2), catalyzes their formation.

  2. Expression of CN2 in clinical colon tumors and colon cancer cell lines was significantly higher than that in normal colon mucosa cell lines. Knockdown of CNDP2 can inhibit the proliferation of colon cancer in vitro and retarded carcinogenesis in vivo.

  3. Results suggest that CNDP2 acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) pathway.

  4. a key role of CNDP2 in PD neurodegeneration, by mechanisms that could involve oxidative stress, protein aggregation or inflammation.

  5. deletion of the CPGL gene is a poor prognostic marker in resected pancreatic cancer, and functional studies suggest the CPGL gene as growth suppressor gene in pancreatic cancer.

  6. Common variants in CNDP1 (show CNDP1 Proteins) and CNDP2 play a role in susceptibility to kidney disease in patients with type 2 diabetes.

  7. the crystal structure of the flop-selective allosteric modulator, PEPA, bound to the binding domains of the GluA2 (show GRIA2 Proteins) and GluA3 (show GRIA3 Proteins) flop isoforms of AMPA (show GRIA3 Proteins) receptors

  8. Our large, comprehensive study did not find an association between the D18S880 microsatellite or any other polymorphisms in the CNDP2-CNDP1 (show CNDP1 Proteins) genomic region and susceptibility for diabetic nephropathy in type 1 diabetes

Mouse (Murine) CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2) interaction partners

  1. These results provide evidence showing that intradimer interaction of H228 with the reaction center of the dimer counterpart is essential to the enzymatic activity of Cn2.

  2. These findings suggest that the transduced PEP-1-PRX2 (show PRRX2 Proteins) has neuroprotective functions against oxidative stress-induced (show SQSTM1 Proteins) cell death in vitro and in vivo

  3. Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.

CNDP2 Protein Profile

Protein Summary

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003

Gene names and symbols associated with CNDP2

  • CNDP dipeptidase 2 (metallopeptidase M20 family) (CNDP2)
  • CNDP dipeptidase 2 (metallopeptidase M20 family) (cndp2)
  • CNDP dipeptidase 2 (metallopeptidase M20 family) a (cndp2a)
  • CNDP dipeptidase 2 (metallopeptidase M20 family) (Cndp2)
  • phosphoenolpyruvate carboxylase1 (pep1)
  • 0610010E05Rik protein
  • C76600 protein
  • Cn2 protein
  • CNDP2 protein
  • cndp2b protein
  • CPGL protein
  • darmin-r protein
  • Dip-2 protein
  • HsT2298 protein
  • Pep-1 protein
  • Pep1 protein
  • PEPA protein
  • pepc protein
  • PEPC1 protein
  • PEPCase protein
  • PPC1 protein
  • PPEPC4 protein
  • wu:fd20d11 protein
  • wu:fe17f09 protein
  • zgc:92569 protein

Protein level used designations for CNDP2

CNDP dipeptidase 2 (metallopeptidase M20 family) , peptidase A , cytosolic non-specific dipeptidase , CNDP dipeptidase 2 , CNDP dipeptidase 2 b , cytosolic nonspecific dipeptidase , CNDP dipeptidase 2 (metallopeptidase M20 family) b , CNDP dipeptidase 2 a , glutamate carboxypeptidase-like protein 1 , peptidase 1 , cytosolic nonspecific dipeptidase 2 , P-pyruvate carboxylase , PEP carboxylase , PEPCase 1 , phosphoenolpyruvate carboxylase 1

GENE ID SPECIES
281388 Bos taurus
327288 Danio rerio
394907 Xenopus (Silurana) tropicalis
421013 Gallus gallus
476166 Canis lupus familiaris
695080 Macaca mulatta
380001 Xenopus laevis
446978 Xenopus laevis
100061697 Equus caballus
100347984 Oryctolagus cuniculus
55748 Homo sapiens
66054 Mus musculus
291394 Rattus norvegicus
512626 Bos taurus
100174694 Pongo abelii
542372 Zea mays
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