CNDP2 Protein (His tag)

Catalog No. ABIN7195144

Product Details

Target: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This CNDP2 protein is labelled with His tag.

Purpose: Recombinant Human CNDP2/CPGL/PEPA Protein (His Tag)

Sequence: Met 1-Asp 475

Characteristics: A DNA sequence encoding the human CNDP2 (CAC69883.1) (Met 1-Asp 475) was expressed, fused with a polyhistidine tag at the C-terminus.

Purity: > 94 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, pH 8.0

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

Alternative Name: CNDP2/CPGL/PEPA (CNDP2 Products)

Synonyms: 0610010E05Rik Protein, C76600 Protein, Cn2 Protein, Dip-2 Protein, Pep-1 Protein, Pep1 Protein, CN2 Protein, CPGL Protein, HsT2298 Protein, PEPA Protein, cn2 Protein, cpgl Protein, darmin-r Protein, CNDP2 Protein, zgc:92569 Protein, wu:fd20d11 Protein, wu:fe17f09 Protein, cndp2b Protein, PEPC1 Protein, PEPCase Protein, PPC1 Protein, PPEPC4 Protein, pepc Protein, carnosine dipeptidase 2 Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) S homeolog Protein, CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog Protein, phosphoenolpyruvate carboxylase 1 Protein, Cndp2 Protein, CNDP2 Protein, cndp2 Protein, cndp2.S Protein, cndp2.L Protein, pep1 Protein

Background:

Background: Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.

Synonym: CN2;CPGL;HEL-S-13;HsT2298;PEPA

Molecular Weight: 54.2 kDa