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anti-Cadherin 5 (CDH5) Antibodies

CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. Additionally we are shipping Cadherin 5 Kits (59) and Cadherin 5 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDH5 12562 P55284
CDH5 307618  
CDH5 1003 P33151
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Top anti-Cadherin 5 Antibodies at antibodies-online.com

Showing 10 out of 308 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells treated with Na3VO4 0.3mM 40', using VE-Cadherin (Phospho-Tyr731) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using VE-Cadherin (Phospho-Tyr731) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of anti-CDH5 Pab (ABIN389186) in 293 cell line lysates (35 µg/lane). CDH5(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Flow cytometric analysis of 293 cells using VE Cadherin Antibody (CDH5) (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse PE FACS Detection of VE-Cadherin in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VE-Cadherin PE-conjugated Monoclonal Antibody. Cells were stained in a buffer containing Ca2+ and Mg2+. 25 Tests Log in to see 6 to 7 Days
$236.25
Details
Human Mouse Un-conjugated Func, IA, ICC, FACS, IHC (fro), IF, IP, IHC, WB 0.05 mg Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated Func, EIA, IHC (fro), IF, IP, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated FACS, ICC, WB Detection of Human VE-Cadherin by Western Blot. Western blot shows lysate of HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human VE-Cadherin Monoclonal Antibody. This experiment was conducted under reducing conditions. VE-Cadherin in HUVEC Cells. VE-Cadherin was detected in immersion fixed HUVEC cells using Mouse Anti-Human VE-Cadherin Monoclonal Antibody. Specific staining was localized to plasma membrane. 100 μg Log in to see 6 to 7 Days
$333.38
Details
Human Mouse Un-conjugated FACS, ELISA, WB 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Cadherin-5 on human endothelial cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of anti-Cadherin-5 antibody. Immunofluorescent staining of Human Fibroblasts with anti-Cadherin-5 antibody. 50 μg Log in to see 5 to 6 Days
$154.07
Details

CDH5 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Cadherin 5 Antibodies

  1. Human Monoclonal Cadherin 5 Primary Antibody for FACS - ABIN4897612 : Ricci-Vitiani, Pallini, Biffoni, Todaro, Invernici, Cenci, Maira, Parati, Stassi, Larocca, De Maria: Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. in Nature 2010 (PubMed)
    Show all 8 references for ABIN4897612

  2. Human Monoclonal Cadherin 5 Primary Antibody for Func, EIA - ABIN1105883 : Martìn-Padura, De Castellarnau, Uccini, Pilozzi, Natali, Nicotra, Ughi, Azzolini, Dejana, Ruco: Expression of VE (vascular endothelial)-cadherin and other endothelial-specific markers in haemangiomas. in The Journal of pathology 1995 (PubMed)
    Show all 5 references for ABIN1105883

  3. Human Monoclonal Cadherin 5 Primary Antibody for IF, IP - ABIN967857 : Corada, Liao, Lindgren, Lampugnani, Breviario, Frank, Muller, Hicklin, Bohlen, Dejana: Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability. in Blood 2001 (PubMed)
    Show all 5 references for ABIN967857

  4. Human Polyclonal Cadherin 5 Primary Antibody for EIA, WB - ABIN357862 : Ali, Liao, Martens, Muller: Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion. in Microcirculation (New York, N.Y. : 1994) 1997 (PubMed)
    Show all 3 references for ABIN357862

  5. Human Monoclonal Cadherin 5 Primary Antibody for FACS, ICC - ABIN4900381 : Lindsley, Gill, Murphy, Langer, Cai, Mashayekhi, Wang, Niwa, Nerbonne, Kyba, Murphy: Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. in Cell stem cell 2008 (PubMed)
    Show all 2 references for ABIN4900381

  6. Human Monoclonal Cadherin 5 Primary Antibody for FACS, ELISA - ABIN1724747 : Shrivastava-Ranjan, Rollin, Spiropoulou: Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin. in Journal of virology 2010 (PubMed)
    Show all 2 references for ABIN1724747

  7. Human Monoclonal Cadherin 5 Primary Antibody for Func, IA - ABIN269580 : Evangelista, Franco, Schwab, Coburn: Leptospira interrogans binds to cadherins. in PLoS neglected tropical diseases 2014 (PubMed)
    Show all 2 references for ABIN269580

  8. Human Monoclonal Cadherin 5 Primary Antibody for FACS, ELISA - ABIN1724748 : Pirotte, Lamour, Lambert, Alvarez Gonzalez, Ormenese, Noël, Mottet, Castronovo, Bellahcène: Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation. in Blood 2011 (PubMed)
    Show all 2 references for ABIN1724748

  9. Human Polyclonal Cadherin 5 Primary Antibody for FACS, WB - ABIN389186 : Breviario, Caveda, Corada, Martin-Padura, Navarro, Golay, Introna, Gulino, Lampugnani, Dejana: Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. in Arteriosclerosis, thrombosis, and vascular biology 1995 (PubMed)

More Antibodies against Cadherin 5 Interaction Partners

Mouse (Murine) Cadherin 5 (CDH5) interaction partners

  1. Galphas (show GNAS Antibodies) depletion blocks the S1PR1 (show S1PR1 Antibodies)-activation induced VE-cadherin stabilization at junctions.

  2. Rab11a/Rab11 (show RAB11A Antibodies) family-interacting protein 2 (show RAB11FIP2 Antibodies)-mediated VE-cadherin recycling is required for formation of adherens junctions and restoration of vascular endothelial barrier integrity.

  3. These findings together demonstrate the essential role of KDM4A (show KDM4A Antibodies) and KDM4C (show KDM4C Antibodies) in orchestrating mESC differentiation to endothelial cells through the activation of Flk1 (show KDR Antibodies) and VE-cadherin promoters, respectively

  4. In the absence of Tie-2 (show TEK Antibodies), VE-PTP (show PTPRB Antibodies) inhibition destabilizes endothelial barrier integrity in agreement with the VE-cadherin-supportive effect of VE-PTP (show PTPRB Antibodies).

  5. identification of novel components of the adherens junction complex, and introduction of a novel molecular mechanism through which the VE-cadherin complex controls YAP (show YAP1 Antibodies) transcriptional activity

  6. Endotoxin challenge initiates interrelated changes in microvessel Cx43 (show GJA1 Antibodies), VE-cadherin, and microvessel permeability, with changes in Cx43 (show GJA1 Antibodies) temporally leading the other responses.

  7. Mutating Y731 in the cytoplasmic tail of VE-cadherin, known to selectively affect leukocyte diapedesis, but not the induction of vascular permeability, attenuates bleeding.

  8. mRNA of HIF-2alpha (show EPAS1 Antibodies) and Ets-1 (show ETS1 Antibodies) were significantly increased by HIF-3alpha ablation. Both factors activate the VE-cadherin gene, the transcriptional repression of these factors by HIF-3alpha is important for silencing the irrelevant expression of the VE-cadherin

  9. iPS (show SLC27A4 Antibodies) cell-derived Flk1 (show KDR Antibodies)(+)VE-cadherin(+) cells expressing the Er71 (show ETV2 Antibodies) are as angiogenic as mES (show PTCH1 Antibodies) cell-derived cells and incorporate into CD31 (show PECAM1 Antibodies)(+) neovessels.

  10. VE-cadherin tyrosine phosphorylation at Y685 is a physiological and hormonally regulated process in female reproductive organs.

Zebrafish Cadherin 5 (CDH5) interaction partners

  1. VE-cadherin/amotL2 (show AMOTL2 Antibodies) complex is responsible for transmitting mechanical force between endothelial cells for the coordination of cellular morphogenesis consistent with aortic lumen expansion and function.

  2. Cdh5 organizes junctional and cortical actin cytoskeletons and F-actin polymerization during endothelial cell elongation.

  3. Regulatory pathways affecting vascular stabilization via VE-cadherin dynamics

  4. suggest that Ve-cadherin and Moesin1 (show MSN Antibodies) function to establish and maintain apical/basal polarity during multicellular lumen formation in the intersegmental vessels

  5. results demonstrate a significant role for VE-cadherin in cardiac development independent of its effects on the formation of the peripheral vasculature

  6. fli1 (show FLI1 Antibodies), and etsrp (show ETV2 Antibodies), demonstrated that erg (show KCNH2 Antibodies) and fli1 (show FLI1 Antibodies) act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin

  7. VE-cadherin plays an essential role in vascular development

Human Cadherin 5 (CDH5) interaction partners

  1. LPA induced disruption and protection of VE-cadherin integrity through LPA(1)-G(i) protein-Rac1-JNK/p38MAPK and LPA(6)-G(12/13) protein-Src-C3G-Rap1 pathways, respectively.

  2. High serum VE-cadherin expression is associated with non-alcoholic fatty liver disease.

  3. CDH5 may play a key role in the progression or metastasis of differentiated-type gastric cancer and serve as a target for its treatment.

  4. PDE4D (show PDE4D Antibodies) acts to allow cAMP-elevating agents to regulate VECADs' role as a sensor of flow-associated fluid shear stress (FSS)-encoded information in arterial endothelial cells.

  5. Data suggest that the microRNA miR (show MLXIP Antibodies)-27a-3p-mediated down-regulation of VE-cadherin and inhibition of epithelial-mesenchymal transition may be essential for Twist-1 (show TWIST1 Antibodies) to induce tumor metastasis and vasculogenic mimicry (VM).

  6. Quaking directly binds to the mRNA of VE-cadherin and beta-catenin (show CTNNB1 Antibodies) and can induce mRNA translation mediated by the 3'UTR (show UTS2R Antibodies) of these genes.

  7. Prophylactic UTI (show AMBP Antibodies) maintains the endothelial barrier function, increases VE-cadherin expression, and inhibits the phosphorylation of VE-cadherin at Tyr658 under inflammatory conditions

  8. BMP-dependent physical interaction of VE-cadherin with the BMP receptor (show BMPR1A Antibodies) ALK2 (show ACRV1 Antibodies) (BMPRI) and BMPRII (show BMPR2 Antibodies), resulting in stabilization of the BMP receptor (show BMPR1A Antibodies) complex and, thereby, the support of BMP6 (show BMP6 Antibodies)-Smad (show SMAD1 Antibodies) signaling.

  9. S-nitrosylation regulates endothelial cell VE-cadherin phosphorylation and internalization in microvascular permeability.

  10. Data indicate that monoclonal antibody (mAb) against vascular endothelial cadherin 5 (VECDH5) has good binding ability and specificity.

Cow (Bovine) Cadherin 5 (CDH5) interaction partners

  1. VE-cadherin induces opposing growth signals.

  2. investigated the role of catenin p120 (show CTNND1 Antibodies)-VE-cadherin interaction in regulation of barrier function in confluent endothelial monolayers

  3. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA (show RHOA Antibodies)

  4. a VE-cadherin-dependent pathway may link T2-TrpRS (show WARS Antibodies) to inhibition of new blood vessel formation

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. exposure of BAECs to hydrostatic pressure (PHYSIOLOGIC PRESSURE) may downregulate the expression of VE-cadherin, resulting in loss of contact inhibition followed by increased proliferation and formation of a multilayered structure

  7. In all, these results demonstrate that cell-cell contact signals through VE-cadherin, RhoA, and intracellular tension in the actin cytoskeleton to regulate proliferation.

Pig (Porcine) Cadherin 5 (CDH5) interaction partners

  1. Low expressions of eNOS3 and Ve-cadherin in the salvaged sub-healthy microvascular endothelium of infarcted and marginal areas suggest that endothelial system is impaired at 7-day of reperfused acute myocardial infarction.

Cadherin 5 (CDH5) Antigen Profile

Protein Summary

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.

Gene names and symbols associated with anti-Cadherin 5 (CDH5) Antibodies

  • cadherin 5, type 2 (vascular endothelium) (CDH5) antibody
  • cadherin 5 (Cdh5) antibody
  • cadherin 5 (cdh5) antibody
  • cadherin 5, type 2 (vascular endothelium) (Cdh5) antibody
  • 7B4 antibody
  • AA408225 antibody
  • cadherin-5 antibody
  • CD144 antibody
  • VE-Cad antibody
  • Vec antibody
  • VEcad antibody
  • VECD antibody
  • wu:fc88a07 antibody

Protein level used designations for anti-Cadherin 5 (CDH5) Antibodies

cadherin 5, type 2, VE-cadherin (vascular endothelium) , cadherin 5, type 2, VE-cadherin (vascular epithelium) , 7B4/cadherin-5 , VE-cadherin , cadherin-5 , vascular endothelial cadherin , VE-cadherin (vascular epithelium) , fc88a07 , type 2 , vecdn , 7B4 antigen , cd144 antigen , endothelial-specific cadherin , VE cadherin

GENE ID SPECIES
467991 Pan troglodytes
12562 Mus musculus
307618 Rattus norvegicus
445471 Danio rerio
1003 Homo sapiens
414735 Bos taurus
100727685 Cavia porcellus
414737 Sus scrofa
489775 Canis lupus familiaris
374068 Gallus gallus
101107462 Ovis aries
Selected quality suppliers for anti-Cadherin 5 (CDH5) Antibodies
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