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Cannabinoid Receptor 1 Proteins (CNR1)

CNR1 encodes one of two cannabinoid receptors. Additionally we are shipping CNR1 Antibodies (146) and CNR1 Kits (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNR1 1268 P21554
CNR1 25248 P20272
CNR1 12801 P47746
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Top CNR1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Rat T7 tag,His tag   100 μg Log in to see 11 to 13 Days
$792.00
Details

CNR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Cannabinoid Receptor 1 (CNR1) Interaction Partners

Cow (Bovine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. Anandamide, through CB1 and TRPV1 (show TRPV1 Proteins) activation, is involved in sperm release from the oviductal reservoir.

Zebrafish Cannabinoid Receptor 1 (CNR1) interaction partners

  1. genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Proteins)) activity disrupts liver development and metabolic function in zebrafish.

  2. CB1 function is required in the early embryo for axonal growth and fasciculation.

Human Cannabinoid Receptor 1 (CNR1) interaction partners

  1. CRIP1a (show CRIP1 Proteins) can compete with beta-arrestins for interaction with C-terminal CB1R domains that could affect agonist-driven, beta-arrestin-mediated internalization of the CB1R.

  2. These findings indicate that D2 antagonism, like D2 agonists, change agonist-mediated CB1 coupling and signaling.

  3. there was a significant reduction in CB1 receptor gene expression levels in cancer tissue compared to normal surrounding mucosa of patients with CRC (show CALR Proteins), confirming that in cancer the "protective" action of the CB1 receptor is lost.

  4. This study demonstrated that CB1 receptor up regulation in Human Stroke.

  5. We hypothesize that high expression levels of CNR1 provide tumor susceptibility to the antitumor effects of circulating endocannabinoids like anandamide, resulting in tumor involution of pediatric low-grade gliomas

  6. evaluation of CB1R expression status in biopsy specimens of esophageal squamous cell carcinoma using immunohistochemistry might be clinically useful for prediction of metastasis to lymph nodes and distant organs

  7. Data indicate that mobile tongue squamous cell carcinoma (SCC (show CYP11A1 Proteins)) patients presenting enhanced cannabinoid receptors CB1R, CB2R (show CNR2 Proteins), or concomitant CB1R/CB2R (show CNR2 Proteins) expression showed significantly longer overall and disease-free survival times compared to those with low expression.

  8. This is the first demonstration that the fibroblasts of the muscular fasciae express CB1 and CB2 (show CNR2 Proteins).

  9. Epistatic interaction between the 1359 G/A polymorphism of the CNR1 gene and the DRD2 (show DRD2 Proteins) gene polymorphisms may be associated with cannabis addiction phenotype in a Turkish population.

  10. in the group of all HD patients, a significantly higher incidence of GA genotype and lower incidence in GG genotype in the polymorphism rs806381s were revealed versus the control group (p = 0.04). It seems that polymorphisms of the CNR1 gene are not associated with uremic pruritus.

Mouse (Murine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. This study demonstrated that CB1 receptor mediated respiratory depression by endocannabinoids.

  2. there was a significant reduction in CB1 receptor gene expression levels in cancer tissue compared to normal surrounding mucosa of patients with CRC, confirming that in cancer the "protective" action of the CB1 receptor is lost.

  3. CB1 receptor tolerance does not occur in aged mice pretreated with Delta(9)-tetrahydrocannabinol and in young adult mice treated with a low dose of the monoacylglycerol lipase (show MGLL Proteins) inhibitor JZL 184.

  4. CB1R expression contributes to the development of persistent mechanical hypersensitivity.

  5. Findings suggest a minor role for the CB2 (show CNR2 Proteins) receptor in the therapeutic effect of the cannabis-based medicine in AbetaPP/PS1 (show PSEN1 Proteins) transgenic mice, but also constitute evidence of a link between CB2 (show CNR2 Proteins) receptor and Abeta (show APP Proteins) processing

  6. Suggest that the CB1R is involved in auditory processing using CB1R knockout mice.

  7. CB1 activation negatively impacts GLP-1R (show GLP1R Proteins)-mediated insulin (show INS Proteins) secretion.

  8. Study showed that basolateral amygdala alpha2-adrenergic receptors may be involved in context- but not tone-dependent fear memory impairment induced by activation of CB1 receptors

  9. Adult female Cnr1 knockouts do not exhibit increased anxiety as in adult male Cnr1 knockouts; adult female ovariectomy does not increase anxiety-like behavior in Cnr1 knockouts; Cnr1 antagonism increases anxiety-like behavior in C57BL/6J mice

  10. Results provide clear evidence that the endocannabinoid system, through CB1 receptors, participates in the different stages of short- and long-term memory-related behavior

Pig (Porcine) Cannabinoid Receptor 1 (CNR1) interaction partners

  1. The endocannabinoid system in renal cells: regulation of sodium transport by CB1 receptors through distinct cell signaling pathways

Rhesus Monkey Cannabinoid Receptor 1 (CNR1) interaction partners

Xenopus laevis Cannabinoid Receptor 1 (CNR1) interaction partners

  1. CB1 functionality increased with development at both central and peripheral level.

CNR1 Protein Profile

Protein Summary

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

Gene names and symbols associated with Cannabinoid Receptor 1 Proteins (CNR1)

  • cannabinoid receptor 1 (brain) (CNR1)
  • cannabinoid receptor 1 (cnr1)
  • cannabinoid receptor 1 (LOC540382)
  • cannabinoid receptor 1 (brain) (Cnr1)
  • cannabinoid receptor 1 (brain) (cnr1)
  • CANN6 protein
  • CB-R protein
  • CB1 protein
  • CB1A protein
  • CB1K5 protein
  • CB1R protein
  • CNR protein
  • CNR1 protein
  • cnr1-A protein
  • LOC540382 protein
  • SKR6R protein

Protein level used designations for Cannabinoid Receptor 1 Proteins (CNR1)

cannabinoid receptor 1 (brain) , cannabinoid receptor (brain) , CB1R , cb1 , cannabinoid receptor 1 , cannabinoid receptor 1-like , central cannabinoid receptor , CB-R , CB1 , brain-type cannabinoid receptor , striatal cannabinoid receptor type 1 protein , cannabinoid 1 receptor , CB1 cannabinoid receptor , cannabinoid receptor CB-1 , cannabinoid receptor 1/CB1

GENE ID SPECIES
281087 Bos taurus
404209 Danio rerio
540382 Bos taurus
100065681 Equus caballus
100393865 Callithrix jacchus
100483374 Ailuropoda melanoleuca
1268 Homo sapiens
25248 Rattus norvegicus
12801 Mus musculus
481913 Canis lupus familiaris
493926 Felis catus
100169690 Cavia porcellus
100520160 Sus scrofa
100299449 Bos taurus
428633 Gallus gallus
101111639 Ovis aries
751607 Taeniopygia guttata
472066 Pan troglodytes
574142 Macaca mulatta
373759 Xenopus laevis
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