CNR1 Protein
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- Target See all CNR1 Proteins
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CB1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CNR1 Protein
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Cannabinoid Receptor 1 (CNR1) (AA 1-110) protein (GST tag)
CNR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Cannabinoid Receptor 1 (CNR1) protein (Fc Tag)CNR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Cannabinoid Receptor 1 (CNR1) (AA 1-472) protein (GST tag)CNR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Cannabinoid Receptor 1 (CNR1) (AA 1-117) protein (His tag)Crystallography grade CNR1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cannabinoid Receptor 1 (CNR1) (AA 1-472) protein (Strep Tag)Crystallography grade CNR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cannabinoid Receptor 1 (CNR1) (AA 1-473) protein (Strep Tag)Crystallography grade CNR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Alternative Name
- CB1 (CNR1 Products)
- Synonyms
- CANN6 Protein, CB-R Protein, CB1 Protein, CB1A Protein, CB1K5 Protein, CB1R Protein, CNR Protein, SKR6R Protein, cnr1-A Protein, cannabinoid receptor 1 Protein, cannabinoid receptor 1 (brain) Protein, cannabinoid receptor 1 (brain) S homeolog Protein, CNR1 Protein, Cnr1 Protein, cnr1 Protein, cnr1.S Protein
- Background
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CANN6, CB-R, CNR1, CB1A, CB1K5, CB1R, CNR
Description: The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. - Molecular Weight
- The human full length CB1 Protein has a MW of 52.7 kDa
- UniProt
- P21554
- Pathways
- Feeding Behaviour
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