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CNDP1 encodes a member of the M20 metalloprotease family. Additionally we are shipping Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Antibodies (82) and Carnosine Dipeptidase 1 (Metallopeptidase M20 Family) Kits (11) and many more products for this protein.
Showing 9 out of 10 products:
Human CNDP1 Protein expressed in HEK-293 Cells - ABIN2180890
Lenney, George, Weiss, Kucera, Chan, Rinzler: Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium. in Clinica chimica acta; international journal of clinical chemistry 1982
Show all 4 references for ABIN2180890
Mouse (Murine) CNDP1 Protein expressed in Human Cells - ABIN2008450
Riedl, Koeppel, Brinkkoetter, Sternik, Steinbeisser, Sauerhoefer, Janssen, van der Woude, Yard: A CTG polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells. in Diabetes 2007
Show all 3 references for ABIN2008450
Human CNDP1 Protein expressed in Human Cells - ABIN2002023
Sauerhöfer, Yuan, Braun, Deinzer, Neumaier, Gretz, Floege, Kriz, van der Woude, Moeller: L-carnosine, a substrate of carnosinase-1, influences glucose metabolism. in Diabetes 2007
Show all 3 references for ABIN2002023
Data shows that higher carnosine content in human skeletal muscle is positively associated with insulin (show INS Proteins) resistance and fasting metabolic preference for glucose.
In gastrointestinal cancer, reduced plasma levels of CNDP1 associate with signs of catabolism and poor outcome.
Alterations of serum carnosinase (CN1) activity has been associated with several pathological conditions, such as neurological disorders, chronic diseases and cancer
Rs12604675-A in CNDP1 may confer susceptibility to overt proteinuria in Japanese women with type 2 diabetes.
In this review, correlations between serum carnosine and carnosinase activity and polymorphism in CNDP1 gene are analyzed. The role of CNDP1 gene polymorphism the development of diabetic nephropathy and non-diabetic chronic kidney disease is discussed.
Plasma levels of FLT (show FLT1 Proteins) and S100A9 (show S100A9 Proteins) proteins are up-regulated and CNDP1 levels are down-regulated in patients with glioblastoma.
Common variants in CNDP1 and CNDP2 (show CNDP2 Proteins) play a role in susceptibility to kidney disease in patients with type 2 diabetes.
These findings provide nominal evidence supporting a role between CNDP1 variants and diabetic kidney disease.
neither CNDP1 genotype nor the normal variation in circulating testosterone levels affects the muscular carnosine content
Serum histidine dipeptide concentrations are not correlated to serum carnosinase activity
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region.
carnosine dipeptidase 1 (metallopeptidase M20 family)
, beta-Ala-His dipeptidase
, CNDP dipeptidase 1
, carnosinase 1
, glutamate carboxypeptidase-like protein 2
, serum carnosinase