anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) Antibodies

CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Additionally we are shipping Caspase 14, Apoptosis-Related Cysteine Peptidase Kits (44) and Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CASP14 12365 O89094
CASP14 299587  
CASP14 23581 P31944
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Top anti-Caspase 14, Apoptosis-Related Cysteine Peptidase Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Mouse Un-conjugated IF, WB 0.1 mg Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of to CASP14 on HeLa cell . CASP14 monoclonal antibody (M01), clone 4C9 Western Blot analysis of CASP14 expression in MCF-7. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Western Blot: Caspase-14 Antibody [NBP1-03128] - Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with caspase-14 antibody. Immunohistochemistry-Paraffin: Caspase-14 Antibody [NBP1-03128] - Staining of human skin. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Dog Rabbit Un-conjugated IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Caspase-14 Antibody [ABIN42880636] - Formalin-fixed paraffin-embedded sections from a human ovarian cancer tissue microarray stained for Caspase-14 expression using this antibody at 1:2000. Low (A) and high (B) stage ovarian tumor tissue cores. High magnification from areas of the tissue cores (A1 and B1). Decreased Caspase-14 expression was seen in the high grade, compared to the low grade tumor. Hematoxylin-eosin counterstain. Immunohistochemistry-Paraffin: Caspase-14 Antibody [ABIN42880636] - Tissue sections of human cervix stained using this antibody at 1:2000. A. Normal cervix (squamous epithelium). B. CIN1 (low-grade squamous intraepithelial lesion, mild dysplasia). C. CIN2 (high-grade squamous intraepithelial lesion, moderate dysplasia. D. CIN3 (high-grade squamous intraepithelial lesion; severe dysplasia-carcinoma in situ. In normal cervi, caspase-14 staining was found most in the midzone layer, but was absent from the basal/parabasal cell layer where mitotically active cells are known to reside. This suggests induction of caspase-14 expression with differentiation. Caspase-14 expression declined progressively during malignant transformation as the histologic severity of the cervical atypia advanced from CIN1 to CIN3. Hematoxylin-eosin counterstain. 0.05 mL Log in to see 7 to 9 Days
$317.63
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Caspase-14 antibody, IHC(P) IHC(P): Human Oesophagus Squama Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

CASP14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)


Human , , , ,
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Top referenced anti-Caspase 14, Apoptosis-Related Cysteine Peptidase Antibodies

  1. Human Monoclonal CASP14 Primary Antibody for IF, WB - ABIN393215 : Kim, Park, Kim, Lee, Lim, Song, Yoo, Lee: Mutational analysis of caspase genes in prostate carcinomas. in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 (PubMed)
    Show all 5 references for 393215

  2. Dog (Canine) Polyclonal CASP14 Primary Antibody for IHC, IHC (p) - ABIN4288063 : Krajewska, Kim, Shin, Kennedy, Duffy, Wong, Marr, Mikolajczyk, Shabaik, Meinhold-Heerlein, Huang, Banares, Hedayat, Reed, Krajewski: Tumor-associated alterations in caspase-14 expression in epithelial malignancies. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)
    Show all 4 references for 4288063

  3. Human Polyclonal CASP14 Primary Antibody for WB - ABIN1686067 : Sundararajan, White: E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis. in Journal of virology 2001 (PubMed)
    Show all 2 references for 1686067

  4. Human Polyclonal CASP14 Primary Antibody for IHC (p), IHC - ABIN315654 : Mcheik, Barrault, Pedretti, Garnier, Juchaux, Levard, Morel, Lecron, Bernard: Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts. in Journal of tissue engineering and regenerative medicine 2016 (PubMed)
    Show all 2 references for 315654

  5. Human Polyclonal CASP14 Primary Antibody for WB - ABIN318746 : Park, Kuechle, Choe, Craik, Lawrence, Presland: Expression and characterization of constitutively active human caspase-14. in Biochemical and biophysical research communications 2006 (PubMed)

  6. Human Monoclonal CASP14 Primary Antibody for IF, WB - ABIN567789 : Pistritto, Jost, Srinivasula, Baffa, Poyet, Kari, Lazebnik, Rodeck, Alnemri: Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. in Cell death and differentiation 2002 (PubMed)

  7. Human Monoclonal CASP14 Primary Antibody for ELISA - ABIN1999341 : Hu, Snipas, Vincenz, Salvesen, Dixit: Caspase-14 is a novel developmentally regulated protease. in The Journal of biological chemistry 1998 (PubMed)

More Antibodies against Caspase 14, Apoptosis-Related Cysteine Peptidase Interaction Partners

Mouse (Murine) Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. Mesotrypsin (show PRSS3 Antibodies) generated saposins A-D from prosaposin (show PSAP Antibodies), and mature caspase-14 contributed to this process by activating mesotrypsinogen (show PRSS3 Antibodies) to mesotrypsin (show PRSS3 Antibodies). Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  2. caspase-14 overexpression is not the cause of utricle formation

  3. Caspase-14-deficient mice are more prone to the development of parakeratosis.

  4. Mere impairment of filaggrin (show FLG Antibodies) degradation by loss of caspase 14 does not influence the inflammatory threshold of atopic dermatitis.

  5. Caspase-14 is required for filaggrin (show FLG Antibodies) degradation to natural moisturizing factors in the skin.

  6. Transcript profiling studies identified caspase (show GATA3 Antibodies)-14 as a novel downstream target of Gata-3, in keeping with its roles in differentiation (show GATA3 Antibodies) and tumorigenesis.

  7. We investigated whether cardiac autonomic control is impaired during sleep in ob/ob mice with morbid obesity caused by congenital leptin (show LEP Antibodies) deficiency.

  8. processing of caspase 14 in epidermal differentiation

  9. SH2-B (show SH2B1 Antibodies) dramatically enhanced leptin (show LEP Antibodies)-stimulated tyrosine phosphorylation of IRS1 (show IRS1 Antibodies) and IRS2 (show IRS2 Antibodies) in human and mouse cells (this is supposed to be a NEWENTRY for mice--SH2-B (show SH2B1 Antibodies)).

  10. Caspase-14, but not caspase-3 (show CASP3 Antibodies) activation coincides temporally and spatially with embryonic KC differentiation, suggesting a role for caspase-14 in terminally differentiated KC.

Human Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) interaction partners

  1. overexpression of S100A7 (show S100A7 Antibodies) in A431 skin squamous carcinoma cells significantly promoted cell proliferation in vitro and tumor growth in vivo, whereas it suppressed the expression of GATA-3 (show GATA3 Antibodies) and caspase-14

  2. caspase-14 contributes to retinal pigment epithelium cell barrier disruption under hyperglycemic conditions.

  3. Caspase-14 was decreased in inflammatory lesions compared to non-lesion in atopic dermatitis. The amount of caspase-14 in the lesions correlated with clinical severity as determined by eczema area and severity index score and the skin barrier functions.

  4. Mesotrypsin (show PRSS3 Antibodies) generated saposins A-D from prosaposin (show PSAP Antibodies), and mature caspase-14 contributed to this process by activating mesotrypsinogen (show PRSS3 Antibodies) to mesotrypsin (show PRSS3 Antibodies). Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.

  5. partial loss of caspase 14 is not associated with dedifferentiation in neoplastic lesions of the oral mucosa

  6. genetic polymorphisms in AICDA (show AICDA Antibodies) and CASP14 are associated with risk for brain tumor in Korean children.

  7. Suggest caspase-14 is a marker of human skin differentiation during development.

  8. Results suggest that caspase-14 may interact with GCM1 (show GCM1 Antibodies) to participate in syncytiotrophoblast differentiation during placental development.

  9. ceramides, an important structural lipid, stimulate caspase-14 expression, coordinating formation of lipid lamellar membranes with the formation of corneocytes

  10. Caspase-14 might play a significant role in the pathogenesis of diabetic retinopathy by accelerating retinal endothelial and epithelial cells death.

Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) Antigen Profile

Protein Summary

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Gene names and symbols associated with CASP14

  • caspase 14 (CASP14) antibody
  • caspase 14 (Casp14) antibody
  • caspase 14 (LOC100101622) antibody
  • caspase 14, apoptosis-related cysteine peptidase (CASP14) antibody
  • caspase 14, apoptosis-related cysteine peptidase (Casp14) antibody
  • caspase-14-like (LOC485601) antibody
  • caspase-15 (LOC780455) antibody
  • CASP14 antibody
  • MICE antibody
  • mini-ICE antibody

Protein level used designations for CASP14

caspase 14 , CASP-14 , caspase-14 , apoptosis-related cysteine protease , caspase 14, apoptosis-related cysteine protease

GENE ID SPECIES
100012133 Monodelphis domestica
12365 Mus musculus
299587 Rattus norvegicus
100101622 Oryctolagus cuniculus
23581 Homo sapiens
100715745 Cavia porcellus
517658 Bos taurus
485601 Canis lupus familiaris
780455 Ovis aries
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