Catenin (Cadherin-Associated Protein), alpha-Like 1 Proteins (CTNNAL1)

May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) (By similarity).. Additionally we are shipping CTNNAL1 Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CTNNAL1 CTNNAL1 298019  
CTNNAL1 54366 O88327
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Top CTNNAL1 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

CTNNAL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Catenin (Cadherin-Associated Protein), alpha-Like 1 (CTNNAL1) Interaction Partners

Mouse (Murine) Catenin (Cadherin-Associated Protein), alpha-Like 1 (CTNNAL1) interaction partners

  1. Force-dependent conformational switch of alpha-catenin (show CTNNA1 Proteins) controls vinculin (show VCL Proteins) binding.

  2. Alpha-catenin (show CTNNA1 Proteins) has a novel role in fine-tuning of tissues' viscosity and surface tension through contractility.

  3. the interaction between alpha-catulin and alpha-dystrobrevin (show DTNA Proteins) is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin (show DMD Proteins) complex

  4. We observed the temporal and spatial distribution of CTNNAL1 expression in mouse lung tissue with the OVA-sensitized asthma model and found that the level of CTNNAL1 mRNA showed a prominent negative correlation with pulmonary resistance.

  5. This study identifies the E-cadherin (show CDH1 Proteins)/catenin complex as a discriminative, partly polyamine-regulated feature of IL-4 (show IL4 Proteins)/IL-13 (show IL13 Proteins)-exposed alternatively activated macrophages

Human Catenin (Cadherin-Associated Protein), alpha-Like 1 (CTNNAL1) interaction partners

  1. These data indicated that upregulated expression of alpha-catulin protein might have impact on the tumorigenesis of head and neck squamous cell carcinoma

  2. Alpha-catulin contributes to drug-resistance of melanoma by activating NF-kappaB (show NFKB1 Proteins) and AP-1 (show FOSB Proteins)

  3. these results strongly indicate that alpha-catulin contributes to the invasive behavior of metastatic cells and may be used as a prognostic marker and future therapeutic target for patients with cancer.

  4. our study shows that alpha-catulin plays a critical role in cancer metastasis

  5. findings show that alpha-catulin is highly expressed in melanoma cells; expression of alpha-catulin promoted melanoma progression and occurred concomitantly with the downregulation of E-cadherin (show CDH1 Proteins) and the upregulation of expression of mesenchymal genes

  6. a robust transcriptional CTNNAL1 up-regulation occurs during acute ozone-induced stress and is mediated at least in part by ozone-induced recruitments of LEF-1 (show LEF1 Proteins) and AP-2alpha (show TFAP2A Proteins) to the human CTNNAL1 promoter

  7. Study provides evidence that alpha-catulin promotes tumor growth by preventing cellular senescence and suggests that downregulating alpha-catulin may be a promising therapeutic approach for cancer treatment.

  8. Data show that alpha-dystrobrevin (show DTNA Proteins)-1 recruits alpha-catulin, which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.

  9. the Lbc/alpha-catulin axis participates in 5-HT (show DDC Proteins)-induced PASMC mitogenesis and RhoA (show RHOA Proteins)/ROCK signaling, and may be an interventional target in diseases involving vascular smooth muscle remodeling.

  10. alpha-catulin maps precisely to the familial dysautonomia candidate region on 9q31.

CTNNAL1 Protein Profile

Protein Summary

May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) (By similarity).

Gene names and symbols associated with CTNNAL1

  • catenin alpha-like 1 (Ctnnal1)
  • catenin alpha-like 1 S homeolog (ctnnal1.S)
  • catenin alpha like 1 (CTNNAL1)
  • catenin alpha-like 1 (ctnnal1)
  • alpha-catulin (LOC100548949)
  • catenin (cadherin associated protein), alpha-like 1 (Ctnnal1)
  • ACRP protein
  • AI616177 protein
  • alpha-CATU protein
  • AW545119 protein
  • C86009 protein
  • Catnal1 protein
  • CLLP protein
  • CTNNAL1 protein
  • DKFZp468D066 protein
  • MGC78800 protein

Protein level used designations for CTNNAL1

alpha-catulin , catenin alpha-like 1 , catenin (cadherin-associated protein), alpha-like 1 , Alpha-catulin , alpha-catenin related protein , alpha-catenin-related protein , catenin alpha-like protein 1 , ACRP , alpha2-catulin

298019 Rattus norvegicus
446448 Xenopus laevis
610662 Canis lupus familiaris
710389 Macaca mulatta
100010644 Monodelphis domestica
100059165 Equus caballus
100125045 Xenopus (Silurana) tropicalis
100172294 Pongo abelii
100548949 Meleagris gallopavo
100585334 Nomascus leucogenys
100626033 Sus scrofa
54366 Mus musculus
8727 Homo sapiens
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