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Cathepsin B Proteins

(Cathepsin B (CTSB))
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) (ABIN2752768)

CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) Cathepsin B Protein (CTSB) (AA 224-333) (GST tag) (ABIN1350704)

CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) (ABIN1350702)

CTSB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Cathepsin B Proteins by Grade

Find Cathepsin B Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Cathepsin B Proteins by Origin

Find Cathepsin B Proteins for a variety of species such as anti-Human Cathepsin B, anti-Mouse Cathepsin B, anti-Rat Cathepsin B. The species listed below are among those available. Click on a link to go to the corresponding products.

Cathepsin B Proteins by Source

Here you will find Cathepsin B Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Cathepsin B Proteins by Protein Type

Here you can find Cathepsin B Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Cathepsin B Proteins by Application

Find Cathepsin B Proteins validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Cathepsin B Proteins by Biological Activity

Find Cathepsin B Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Cathepsin B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752768
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350704
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350702
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320464
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7194669
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7321072
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090923
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3132803
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090924
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090922
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132804
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132802
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2180942
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (1)
Cat. No. ABIN1046771
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7519744
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Cathepsin B Proteins

Hartmann, Lopez Cruz, Alameh, Ho, Rabideau, Pentelute, Bradley, Martchenko: "Characterization of Novel Piperidine-Based Inhibitor of Cathepsin B-Dependent Bacterial Toxins and Viruses." in: ACS infectious diseases, Vol. 4, Issue 8, pp. 1235-1245, (2018) (PubMed).

Peng, Zhang, Zheng, Liang, Li, Chen, Guo, Yoshina, Chen, Zhao, Wu, Liu, Mitani, Yu, Xue: "Cysteine protease cathepsin B mediates radiation-induced bystander effects." in: Nature, Vol. 547, Issue 7664, pp. 458-462, (2017) (PubMed).

Zilbermintz, Leonardi, Jeong, Sjodt, McComb, Ho, Retterer, Gharaibeh, Zamani, Soloveva, Bavari, Levitin, West, Bradley, Clubb, Cohen, Gupta, Martchenko: "Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting." in: Scientific reports, Vol. 5, pp. 13476, (2015) (PubMed).

Chowdhury, Moya, Bhilocha, McMillan, Vigliarolo, Zehbe, Phenix: "Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins." in: Journal of medicinal chemistry, Vol. 57, Issue 14, pp. 6092-104, (2014) (PubMed).

Zhao, Hua, Crowley, Ru, Ni, Shaw, Jiao, Ding, Qu, Hung, Huang, Liu, Ye, Ouyang, Cheng, Liu: "Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage." in: Cell research, Vol. 24, Issue 3, pp. 344-58, (2014) (PubMed).

Cao, Taggart, Berquin, Moin, Fong, Sloane: "Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene." in: Gene, Vol. 139, Issue 2, pp. 163-9, (1994) (PubMed).

Chan, San Segundo, McCormick, Steiner: "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 20, pp. 7721-5, (1986) (PubMed).

Aliases for Cathepsin B Proteins

cathepsin B (CTSB) Proteins
cathepsin B (Ctsb) Proteins
cathepsin B S homeolog (ctsb.S) Proteins
cathepsin B (LOC692390) Proteins
APPS Proteins
apps Proteins
CB Proteins
CPSB Proteins
cpsb Proteins
CTSB Proteins
LOC692390 Proteins
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