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anti-Cell Division Cycle 27 (CDC27) Antibodies

The protein encoded by CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2.

list all antibodies Gene Name GeneID UniProt
CDC27 217232 A2A6Q5
CDC27 996 P30260
CDC27 360643 Q4V8A2
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Top anti-CDC27 Antibodies at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IF, IP, IHC, ELISA, WB 200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated 50 μL Log in to see 9 to 19 Days
$417.00
Details

CDC27 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


Rat (Rattus)


More Antibodies against CDC27 Interaction Partners

Mouse (Murine) Cell Division Cycle 27 (CDC27) interaction partners

  1. Cdc27 directs cyclin D1 (show CCND1 Antibodies) to alternative degradation by anaphase promoting complex/cyclosome.

Human Cell Division Cycle 27 (CDC27) interaction partners

  1. miR (show MLXIP Antibodies)-27a could modulate proliferation and radiosensitivity of TNBC cells. CDC-27 is a direct target of miR (show MLXIP Antibodies)-27a and its downregulation conferred increased radioresistance of the cells.

  2. These findings suggested that polymorphisms in cdc27 may contribute to the susceptibility of BC though functional studies are needed to further elucidate the underling mechanisms of the associations

  3. The structures show how one APC16 binds asymmetrically to the symmetric APC3 dimer and, together with biochemistry and prior data, explain how APC16 recruits APC7 (show ANAPC7 Antibodies) to APC3.

  4. Low cdc27 and high securin (show PTTG1 Antibodies) expression predict short survival for breast cancer patients.

  5. Down-regulation of CDC27 protein is associated with radiation resistance.

  6. Data indicate that additional density present in the anaphase-promoting complex (APC (show APC Antibodies)/C) structure, proximal to Apc3/Cdc27 of the (tetratricopeptide repeat) lobe, is assigned to the TPR subunit Apc7 (show ANAPC7 Antibodies), a subunit specific to vertebrate APC (show APC Antibodies)/C.

  7. the biochemical, structural, and cellular determinants of the novel interaction between MCPH1 (show MCPH1 Antibodies) and Cdc27 and suggest that this interaction may occur within the larger context of MCPH1 (show MCPH1 Antibodies)-APC (show APC Antibodies)/C.

  8. phosphorylation of Cdc27 by CKII (show CSNK2A1 Antibodies) is involved in TGF-beta (show TGFB1 Antibodies)-induced activation of APC (show APC Antibodies).

  9. Cdc20 (show CDC20 Antibodies) requires APC3 and APC8 (show CDC23 Antibodies) to bind and activate the APC (show APC Antibodies)/C when the spindle assembly checkpoint is satisfied, but only APC8 (show CDC23 Antibodies) when active, and APC10 (show ANAPC10 Antibodies) is crucial for the destruction of cyclin B1 (show CCNB1 Antibodies) and securin (show PTTG1 Antibodies), but not cyclin A (show CCNA2 Antibodies)

  10. the spindle checkpoint may regulate CDC27/APC (show APC Antibodies) activity at mitosis

CDC27 Antigen Profile

Protein Summary

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CDC27

  • cell division cycle 27 (Cdc27) antibody
  • cell division cycle 27 (cdc27) antibody
  • cell division cycle protein 27 (NAEGRDRAFT_82880) antibody
  • cell division cycle protein 27 (LOC100223686) antibody
  • cell division cycle 27 (CDC27) antibody
  • AI452358 antibody
  • ANAPC3 antibody
  • APC3 antibody
  • BC023187 antibody
  • CDC27Hs antibody
  • D0S1430E antibody
  • D17S978E antibody
  • HNUC antibody
  • NUC2 antibody
  • wu:fb54g06 antibody
  • wu:fc88c12 antibody

Protein level used designations for CDC27

cell division cycle 27 homolog , cell division cycle protein 27 homolog , cell division cycle protein 27 , CDC27 homolog , H-NUC , anaphase promoting complex subunit 3 , anaphase-promoting complex subunit 3 , anaphase-promoting complex, protein 3 , nuc2 homolog

GENE ID SPECIES
217232 Mus musculus
30450 Danio rerio
8859235 Naegleria gruberi strain NEG-M
100223686 Taeniopygia guttata
996 Homo sapiens
360643 Rattus norvegicus
Selected quality suppliers for anti-CDC27 (CDC27) Antibodies
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