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Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. Additionally we are shipping Centromere Protein H Kits (18) and Centromere Protein H Proteins (11) and many more products for this protein.
Showing 10 out of 87 products:
Cow (Bovine) Polyclonal CENPH Primary Antibody for WB - ABIN2787617
Liao, Zhang, Zhou, Zimonjic, Mani, Kaba, Gifford, Reinhardt, Popescu, Guo, Eaton, Lodish, Weinberg: Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. in Cancer research 2007
Show all 2 references for ABIN2787617
Human Polyclonal CENPH Primary Antibody for IHC, IHC (p) - ABIN4297684
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
essential role of cenph in mitosis and embryonic development and its association with tumor development
Upregulation of centromere protein H is associated with progression of renal cell carcinoma (show MOK Antibodies)
propose that CSPP1 (show Cspp1 Antibodies) cooperates with CENP-H on kinetochores to serve as a novel regulator of kinetochore microtubule dynamics for accurate chromosome segregation
CENP-H was overexpressed in HCC (show FAM126A Antibodies), and its level of upregulation was an independent prognostic indicator, suggesting that CENP-H may be an effective therapeutic strategy for the treatment of HCC (show FAM126A Antibodies).
CENP-H promotes the proliferation of human gastric cancer cells
High expression of CENP-H in gastric cancer indicates poor prognosis and Survivin (show BIRC5 Antibodies) may mediate its procancer role.
Breast cancer patients with high CENP-H expression had short overall survival. CENP-H expression was related with clinical stage.
upregulated CENP-H and Ki67 (show MKI67 Antibodies) levels are significantly associated with short relapse-free survival in hypopharyngeal squamous cell carcinoma (HSSC); these factors may be predictors of a relapsing phenotype in HSSC cases
Sp1 (show PSG1 Antibodies) and Sp3 (show SP3 Antibodies) bind to the CENPH minimal promoter and function as a regulator of the transcription of CENPH in nasopharyngeal carcinomas.
CENP-H is up-regulated and plays an important role in the aneuploidy frequently observed in colorectal cancers.
The CENP-H-I complex may function, in part, as a marker directing CENP-A (show CENPA Antibodies) deposition to centromeres.
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
centromere protein H
, interphase centromere complex protein 35
, kinetochore protein CENP-H
, centromere autoantigen H