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CCR6 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR6 Kits (21) and CCR6 Proteins (4) and many more products for this protein.
Showing 10 out of 123 products:
Human Monoclonal CCR6 Primary Antibody for FACS - ABIN2661553
Hirota, Yoshitomi, Hashimoto, Maeda, Teradaira, Sugimoto, Yamaguchi, Nomura, Ito, Nakamura, Sakaguchi, Sakaguchi: Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. in The Journal of experimental medicine 2007
Show all 7 references for ABIN2661553
Mouse (Murine) Monoclonal CCR6 Primary Antibody for ICFC - ABIN2657667
Cook, Prosser, Forster, Zhang, Kuklin, Abbondanzo, Niu, Chen, Manfra, Wiekowski, Sullivan, Smith, Greenberg, Narula, Lipp, Lira: CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. in Immunity 2000
Show all 3 references for ABIN2657667
Human Polyclonal CCR6 Primary Antibody for EIA, IHC (fro) - ABIN492854
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
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Human Monoclonal CCR6 Primary Antibody for EIA, WB - ABIN263910
Singh, Zhang, Foley, Hedrick, Farber: Human T cells that are able to produce IL-17 express the chemokine receptor CCR6. in Journal of immunology (Baltimore, Md. : 1950) 2007
Show all 2 references for ABIN263910
Human Polyclonal CCR6 Primary Antibody for IHC (p), WB - ABIN731095
Kalyanasundaram Bhanumathy, Zhang, Xie, Xu, Tan, Xiang: Potent immunotherapy against well-established thymoma using adoptively transferred transgene IL-6-engineered dendritic cell-stimulated CD8(+) T-cells with prolonged survival and enhanced cytotoxicity. in The journal of gene medicine 2015
High CCR6 expression is associated with Inflammatory Bowel Disease.
Tregs of unexplained recurrent miscarriage patients was significantly lower than that in controls. CCL20 (show CCL20 Antibodies)-CCR6 could drive immune activity of CD4 (show CD4 Antibodies)(+)FOXP3 (show FOXP3 Antibodies)(+) Tregs, followed by their migration to the feto-maternal microenvironment
AEG-1 (show MTDH Antibodies) mediates CCL20 (show CCL20 Antibodies)/CCR6-induced EMT (show ITK Antibodies) development via both Erk1/2 (show MAPK1/3 Antibodies) and Akt (show AKT1 Antibodies) signaling pathway in cervical cancer, which indicates that CCL20 (show CCL20 Antibodies)/CCR6-AEG-1 (show MTDH Antibodies)-EMT (show ITK Antibodies) pathway could be suggested as a useful target to affect the progression of cervical cancer.
The involvement of cell surface nucleolin (show NCL Antibodies) in the initiation of CCR6 signaling in human hepatocellular carcinoma.Expression of nucleolin (show NCL Antibodies) and CCR6 correlates with overall survival in hepatocellular carcinoma patients.
Late-onset cytomegalovirus infection was preceded by an immune phenotype characterized by increased CCR6 expression on bulk CD4 (show CD4 Antibodies)(+) T cells following solid organ transplant.
The data reviewed suggest the necessity of evaluation of other blood redox-balance and nitric oxide in psoriasis should with additional investigations to targeting CCR6 rs3093024 in the genetic susceptibility of psoriasis.
the current data demonstrate a genetic association between CCR6 variants and susceptibility to lupus nephritis
Th17 cells are recruited into tumor tissues preferentially through CCR6-CCL20 (show CCL20 Antibodies) pathway
High CCR6 expression is associated with colon cancer.
Leukocytes expressing CCR6 are present in the ovary immediately prior to ovulation.
CCR6 deficiency affects hepatic inflammatory cell recruitment resulting in the promotion of hepatic inflammation and fibrosis.
in mice, activated B cells use the chemokine receptor (show CCR1 Antibodies) CCR6 to access the subepithelial dome (SED) of Peyer's patches.
CCR6 might be crucial for optimal development of Th2 immune responses.
This study delineated for the first time a role for CCR6 in the development of breast cancer.
results suggest a key role for CD28 (show CD28 Antibodies) costimulation in promoting a central Treg to eTreg transition with appropriate upregulation of chemokine (show CCL1 Antibodies) receptors such as CCR6 that are required for tissue homing
CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.
these data indicate that CCR6 has a supplementary role in coordination of early thymocyte precursor migration events important for normal subsequent thymocyte precursor development, but is not required for normal nTreg development.
CCR6 deficieny leads to a diminished cerebral immune response in experimental pneumococcal meningitis.
The results of this study suggest that ccr6 may play a role in cognition and learning behaviour, as well as anxiety and other behaviours.
Chemokine (show CCL1 Antibodies) receptors CCR6 and CXCR3 (show CXCR3 Antibodies) are necessary for CD4 (show CD4 Antibodies)(+) T cell mediated ocular surface disease in experimental dry eye disease.
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
chemokine (C-C motif) receptor 6
, C-C chemokine receptor type 6
, CC chemokine receptor 6
, c-C chemokine receptor type 6-like
, G protein-coupled receptor 29
, G-protein coupled receptor 29
, LARC receptor
, chemokine (C-C) receptor 6
, chemokine receptor-like 3
, seven-transmembrane receptor, lymphocyte, 22