You are viewing an incomplete version of our website. Please click to reload the website as full version.

Chemokine (C-X-C Motif) Receptor 3 Proteins (CXCR3)

CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Antibodies (252) and CXCR3 Kits (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CXCR3 2833 P49682
CXCR3 84475 Q9JII9
CXCR3 12766 O88410
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CXCR3 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

CXCR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)
Mouse (Murine) ,

More Proteins for Chemokine (C-X-C Motif) Receptor 3 (CXCR3) Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. IP-10 (show CXCL10 Proteins) complexes with CXCR3, which in turn activates the ERK1/2 pathway, thus resulting in upregulation of p-CREB (show CREB1 Proteins) and increased vascular smooth muscle cell proliferation.

  2. the CXCR3+/CCR5+ expression was higher in the neoplastic as compared to the hyperplastic nodules.

  3. monocytes and lymphocytes cooperate to enhance migration towards CXCR3 chemokines and CCL5 (show CCL5 Proteins) in COPD (show ARCN1 Proteins)

  4. CXCL10 (show CXCL10 Proteins)/CXCR3 axis promotes gastric cancer cell invasion and migration by upregulating MMP-2 (show MMP2 Proteins) and MMP-9 (show MMP9 Proteins) production via PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway.

  5. CXCR3 expression in chronic lymphocytic leukemia cells was a strong determinant of a worse clinical outcome.

  6. Speculate that aberrant expression of CXCR3 in marginal zone lymphoma of the skin is associated with migration of lymphoma cells to the epidermis and could lead to an epidermotropic pattern.

  7. CXCR3 role in autoimmune thyroiditis [review]

  8. Both CXCL10 (show CXCL10 Proteins) and CXCR3 appeared to be useful in differentiating T1R reaction in borderline leprosy while CXCR3 alone differentiated BT from BT-T1R

  9. CXCR3 expression was upregulated in advanced gastric cancer and was associated with increased CD4 (show CD4 Proteins)+, CD8 (show CD8A Proteins)+ tumor-infiltrating lymphocyte infiltration and improved overall survival

  10. CXCR3 was also linked to steatosis through inducing hepatic lipogenic genes

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. this study shows that diosgenin-mediated anti-allergic effects are associated with increased number of Foxp3 (show FOXP3 Proteins)+ Treg cells expressing CXCR3

  2. Circulating levels of chemokines that activate CXCR3 are elevated in non-obese diabetic (NOD) mice, consistent with clinical findings in human diabetes.

  3. CXCR3 interacts with IL-10 (show IL10 Proteins) secreted by CD8 (show CD8A Proteins)+CD122 (show IL2RB Proteins)+ regulatory T cells in a mouse model of Acute Lung Injury and promotes interferon-gamma (show IFNG Proteins) and CXCL10 (show CXCL10 Proteins) release.

  4. This study demonstrates a previously unrecognized role of CXCR3 signaling in glial cells in negatively regulating Th17 cell expansion during experimental autoimmune encephalomyelitis

  5. CXCR3 was also linked to steatosis through inducing hepatic lipogenic genes

  6. findings demonstrate that targeting CXCR3 is effective in both tumor and host compartments, and suggest that CXCR3 inhibition is likely to avoid adverse effects on host cells

  7. Activation of the CXCL10 (show CXCL10 Proteins)/CXCR3 pathway has an important role in retinal inflammation and neuronal injury after high intraocular pressure-induced ischemia.

  8. STAT3 (show STAT3 Proteins) in CD8 (show CD8A Proteins)+ T Cells Inhibits Their Tumor Accumulation by Downregulating CXCR3/CXCL10 (show CXCL10 Proteins) Axis

  9. CXCR3-mediated trafficking of regulatory T cells could represent a mechanism of homeostatic immunoregulation during diabetogeneesis.

  10. These studies identify CXCR3-mediated trafficking at the tumour vascular interface as a critical checkpoint to effective T-cell-based cancer immunotherapy.

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression

CXCR3 Protein Profile

Protein Summary

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene names and symbols associated with CXCR3

  • chemokine (C-X-C motif) receptor 3 (CXCR3)
  • chemokine (C-X-C motif) receptor 3 (cxcr3)
  • chemokine (C-X-C motif) receptor 3 (Cxcr3)
  • CD182 protein
  • Cd183 protein
  • CKR-L2 protein
  • Cmkar3 protein
  • CXC-R3 protein
  • CXCR-3 protein
  • cxcr3 protein
  • Gpr9 protein
  • IP10-R protein
  • Mig-R protein
  • MigR protein

Protein level used designations for CXCR3

chemokine (C-X-C motif) receptor 3 , C-X-C chemokine receptor type 3 , CXC-R3 , CXCR-3 , G protein-coupled receptor 9 , IP-10 receptor , IP10 receptor , Mig receptor , chemokine (C-X-C) receptor 3 , interferon-inducible protein 10 receptor , CXC chemokine receptor 3 , Interferon-inducible protein 10 receptor

GENE ID SPECIES
465704 Pan troglodytes
496477 Xenopus (Silurana) tropicalis
699438 Macaca mulatta
2833 Homo sapiens
84475 Rattus norvegicus
12766 Mus musculus
497018 Bos taurus
491952 Canis lupus familiaris
100860874 Capra hircus
Selected quality suppliers for CXCR3 Proteins (CXCR3)
Did you look for something else?