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Claudin 6 Proteins (CLDN6)

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping Claudin 6 Antibodies (94) and Claudin 6 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLDN6 9074 P56747
CLDN6 54419 Q9Z262
Rat CLDN6 CLDN6 287098  
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Top Claudin 6 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

CLDN6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Claudin 6 (CLDN6) Interaction Partners

Xenopus laevis Claudin 6 (CLDN6) interaction partners

  1. claudin-6 is expressed in the developing pronephric tubule and duct but not glomus. Knockdown of claudin-6 by specific morpholino led to severe defects in pronephros tubular morphogenesis and blocked the terminal differentiation of the tubule cells.

Human Claudin 6 (CLDN6) interaction partners

  1. Data show that claudin-6 (CLDN6) R209Q and occludin (OCLN (show OCLN Proteins)) P24A mutations do not affect HCV pseudoparticles (HCVpp) entry.

  2. The expression of ASK1 (show MAP3K5 Proteins) is correlated with the level of claudin-6 in cervical carcinoma cells and tissues.

  3. High levels of CLDN6 are associated with non-small-cell lung cancer.

  4. The expression of claudin-6 was down regulated in gastric cancer tissue.

  5. Only some hepatitis C virus strains efficiently use CLDN6 for infection.

  6. This work provides a proof of concept for the use of Claudin-6 to eliminate residual undifferentiated human pluripotent stem cells from culture.

  7. Although claudin-6 and claudin-9 (show CLDN9 Proteins) can serve as entry factors in cell lines, hepatitis C virus infection into human hepatocytes is not dependent on claudin-6 and claudin-9 (show CLDN9 Proteins).

  8. ASK1 (show MAP3K5 Proteins) signal may play a positive role in the inhibitory effect of claudin-6 in breast cancer.

  9. Our results show that claudin-6 protein is significantly down-regulated in breast invasive ductal carcinomas

  10. CLDN6 is not a specific biomarker for atypical teratoid rhabdoid tumors as it is expressed in a variety of other pediatric CNS and soft tissue tumors.

Mouse (Murine) Claudin 6 (CLDN6) interaction partners

  1. Cldn6 is expressed by pulmonary epithelium during lung organogenesis.

  2. The Inv (show INVS Proteins)-Cldn6-CDelta206 transgenic mice displayed a developmental delay in epidermal permeability barrier formation, as shown by the expression of keratins and Cldns, and by X-Gal (show GAL Proteins) penetration assays.

  3. the normally robust injury response mechanism of the epidermis is lost in the aging Involucrin (show IVL Proteins)-Cldn6-CDelta196 transgenic epidermis

  4. Permeability barrier dysfunction in transgenic mice overexpressing claudin 6.

  5. Cldn6 plays a role in the differentiation processes of the epidermis and hair follicle

  6. Claudin-6 mRNA was found to be differentially expressed in four different adipose tissues, and up-regulated in each fat depot of mice fed a high-fat diet. Levels of claudin-6 transcripts were increased during differentiation of 3T3-L1 ce

  7. developmentally expressed claudin isoforms include claudin 6, claudin 9, and claudin 13

  8. Results demonstrate that the overexpression of a tail truncation mutant of claudin 6 (Cldn6) mislocalizes Cldn6 and other Cldn proteins to the cytoplasm and triggers a postnatal increase in proliferation and aberrant differentiation of the epidermis.

  9. Tight junctions containing claudin 6 are essential for blastocyst formation in preimplantation mouse embryos

  10. Expression analysis in mice has shown that Claudin-6 is one of the few genes that allows for the targeting of the definitive endoderm throughout the entire anterior-posterior axis, before and after gut (show GUSB Proteins) tube patterning.

Claudin 6 (CLDN6) Protein Profile

Protein Summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Gene names and symbols associated with Claudin 6 Proteins (CLDN6)

  • claudin 6, gene 1 (cldn6.1)
  • claudin 6 (CLDN6)
  • claudin 6 (Cldn6)
  • AL024037 protein
  • cldn4l2 protein
  • CLDN6 protein

Protein level used designations for Claudin 6 Proteins (CLDN6)

claudin 6 , claudin-6 , skullin , tight junction molecule claudin 6

GENE ID SPECIES
446591 Xenopus laevis
467882 Pan troglodytes
9074 Homo sapiens
54419 Mus musculus
490048 Canis lupus familiaris
511318 Bos taurus
287098 Rattus norvegicus
100302020 Sus scrofa
100735319 Cavia porcellus
101117294 Ovis aries
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