Claudin 6 Protein (CLDN6) (mFc Tag)
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- Target See all Claudin 6 (CLDN6) Proteins
- Claudin 6 (CLDN6)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Claudin 6 protein is labelled with mFc Tag.
- Purpose
- Recombinant human CLDN6 Protein with C-terminal mouse Fc Tag
- Specificity
- CLDN6 (Met1-Ala4) (Gln57-Gln78) (Arg145-Arg158) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CLDN6 Protein
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Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC. ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLPCLDN6 Origin: Cynomolgus Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-219) (Active) protein-VLPCLDN6 Origin: Mouse Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP (Biotin)CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) protein (GST tag)CLDN6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Claudin 6 (CLDN6) (AA 1-220) protein (Strep Tag)Crystallography grade CLDN6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Claudin 6 (CLDN6) (AA 1-219) protein (Strep Tag)Crystallography grade CLDN6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Claudin 6 (CLDN6)
- Alternative Name
- CLDN6 (CLDN6 Products)
- Synonyms
- cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
- Background
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Synonymes: Claudin 6, Claudin-6, Skullin
Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. - Molecular Weight
- predicted molecular mass of 31.6 kDa after removal of the signal peptide.
- Gene ID
- 9074
- UniProt
- P56747
- Pathways
- Hepatitis C
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