Claudin 6 Protein (CLDN6) (His tag,Twin-Strep tag)
-
- Target See all Claudin 6 (CLDN6) Proteins
- Claudin 6 (CLDN6)
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Insect Cells
- Purification tag / Conjugate
- This Claudin 6 protein is labelled with His tag,Twin-Strep tag.
- Purpose
- Human Claudin-6 / CLDN6 Protein, His,Twin-Strep Tag (Detergent)
- Sequence
- Ala 2 - Val 220
- Characteristics
- Human Claudin-6 Protein, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Val 220 (Accession # P56747-1).
- Purity
- 80 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product CLDN6 Protein
-
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC. ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLPCLDN6 Origin: Cynomolgus Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-219) (Active) protein-VLPCLDN6 Origin: Mouse Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP (Biotin)CLDN6 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Claudin 6 (CLDN6) protein (mFc Tag)CLDN6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 6 (CLDN6) (AA 1-220) protein (GST tag)CLDN6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
-
- Comment
-
This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. (10xHis , Twin-Strep) The protein has a calculated MW of 28.3 kDa. The protein migrates as 26-27 kDa under reducing (R) condition (SDS-PAGE).
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
- Storage
- -80 °C
- Storage Comment
- -70°C
-
- Target
- Claudin 6 (CLDN6)
- Alternative Name
- Claudin-6 (CLDN6 Products)
- Synonyms
- cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
- Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.
- Molecular Weight
- 28.3 kDa
- Pathways
- Hepatitis C
-
