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anti-Cofilin 1 (Non-Muscle) (CFL1) Antibodies

The protein encoded by CFL1 can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Additionally we are shipping Cofilin 1 (Non-Muscle) Kits (58) and Cofilin 1 (Non-Muscle) Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CFL1 1072 P23528
CFL1 12631 P18760
CFL1 29271 P45592
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Top anti-Cofilin 1 (Non-Muscle) Antibodies at antibodies-online.com

Showing 10 out of 305 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-Cofilin (Ser3) antibody Phospho-specific Pab (ABIN650888) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in HL-60 cell line lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in mouse NIH-3T3 cell line lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CFL1 Antibody (N-term) (ABIN389443) in MCF-7,Hela cell line and mouse brain tissue lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody.(2 µg/mL) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CFL1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/HeLa cells, using Cofilin Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Dog Mouse Un-conjugated IF, WB Western blot analysis of Cofilin on mouse cerebrum lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10000 dilutuion of anti-Cofilin. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to CFL1 on HeLa cell (antibody concentration 10 µg/mL). CFL1 monoclonal antibody (M04), clone 1A1 Western Blot analysis of CFL1 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details

CFL1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Cofilin 1 (Non-Muscle) Antibodies

  1. Human Monoclonal CFL1 Primary Antibody for IF, WB - ABIN394735 : Garg, Verma, Cook, Soofi, Venkatareddy, George, Mizuno, Gurniak, Witke, Holzman: Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN394735

  2. Dog (Canine) Monoclonal CFL1 Primary Antibody for IF, WB - ABIN968754 : Chan, Bailly, Zebda, Segall, Condeelis: Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. in The Journal of cell biology 2000 (PubMed)
    Show all 3 references for ABIN968754

  3. Human Polyclonal CFL1 Primary Antibody for IHC (p), WB - ABIN197372 : Kobayashi, Nishita, Mishima, Ohashi, Mizuno: MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. in The EMBO journal 2006 (PubMed)
    Show all 3 references for ABIN197372

  4. Human Polyclonal CFL1 Primary Antibody for DB - ABIN650888 : Klemke, Kramer, Konstandin, Wabnitz, Samstag: An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments. in The EMBO journal 2010 (PubMed)
    Show all 3 references for ABIN650888

  5. Human Monoclonal CFL1 Primary Antibody for EIA, IHC (p) - ABIN336102 : Mannherz, Ballweber, Galla, Villard, Granier, Steegborn, Schmidtmann, Jaquet, Pope, Weeds: Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin. in Journal of molecular biology 2007 (PubMed)
    Show all 2 references for ABIN336102

  6. Human Polyclonal CFL1 Primary Antibody for IF, IHC (p) - ABIN319381 : Chen, Cizeau, Vande Velde, Park, Bozek, Bolton, Shi, Dubik, Greenberg: Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for ABIN319381

  7. Human Polyclonal CFL1 Primary Antibody for ELISA, WB - ABIN1534356 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  8. Human Polyclonal CFL1 Primary Antibody for FACS, WB - ABIN650759 : Fazal, Bijli, Minhajuddin, Rein, Finkelstein, Rahman: Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against Cofilin 1 (Non-Muscle) Interaction Partners

Xenopus laevis Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. Results suggest that elevation of actin dynamics by Xenopus ADF/cofilin (XAC) activation through Slingshot phosphatase (XSSH) phosphorylation is required for meiotic spindle assembly.

  2. Gastrulation movement requires ADF/cofilin activity through dynamic regulation of its phosphorylation state.

Zebrafish Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. proper actin turnover mediated by Cfl1 is essential for adhesion between the deep cell layer and the enveloping layer and cell movements during gastrulation in zebrafish

  2. Silencing of cofilin-1 led to an Accumulation of F-actin fibers and significantly decreased podocyte migration. ability

Fruit Fly (Drosophila melanogaster) Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism.

  2. AIP1 enhances cofilin-mediated actin disassembly in the apical region of precluster cells to promote remodeling of adherense junctions.

  3. Data show that cofilin is required for F-actin turnover and lamellipodial protrusion in the border cells.

  4. tsr is required for planar cell polarity patterning.

  5. These results indicate that changes in the extent of cofilin phosphorylation are regulated by Ssh in response to changes in the levels and/or organisation of F-actin.

  6. Results show that twinstar (tsr), which encodes Drosophila cofilin/ADF (actin-depolymerizing factor), is required for elongation of the retinal cell body and the morphogenesis of the rhabdomere.

Human Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. Progesterone (P4) increases human astrocytoma cells migration and invasion through its intracellular receptor, and that cofilin activation by P4 is independent of progesterone receptor (show PGR Antibodies) action.

  2. the presence of the actin-severing protein, cofilin, in human sperm, is reported.

  3. Aurora kinase A (show AURKA Antibodies) has a role in inducing papillary thyroid cancer lymph node metastasis by promoting cofilin-1 activity

  4. analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover

  5. Cofilin 1 activation prevents the defects in axon elongation and guidance induced by extracellular alpha-synuclein (show SNCA Antibodies)

  6. novel roles for actin-depolymerizing factor (show GSN Antibodies) and cofilin-1 in regulating the remodeling and permeability of epithelial junctions

  7. cofilin1 is involved in hypertensive nephropathy by modulating the nuclear translocation of NF-kappaB (show NFKB1 Antibodies) and the expression of its downstream inflammatory factors in renal tubular epithelial cells

  8. Cofilin-1 and transgelin (show TAGLN Antibodies) may play roles in the carcinogenesis and development of esophageal squamous cell carcinoma

  9. results demonstrate that in VSMCs mechanical stimulation activates cofilin by a Nox4 (show NOX4 Antibodies)-dependent mechanism and that this pathway is required for cytoskeleton reorganization and cell reorientation

  10. Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.

Cow (Bovine) Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. Myosin phosphatase and cofilin mediate cAMP/cAMP-dependent protein kinase-induced decline in endothelial cell isometric tension and myosin II regulatory light chain phosphorylation

  2. Cyclic compression for 10 min up-regulated gene expression for the actin depolymerising proteins, cofilin and destrin (show DSTN Antibodies).

Mouse (Murine) Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. Caspase-11 (show CASP4 Antibodies) targets cofilin via the RhoA GTPase, whereas caspase-1 (show CASP1 Antibodies) engages the Slingshot phosphatase

  2. aberrant cofilin phosphorylation that induces actin polymerization might be a consequence of actin disassembly induced by the absence of Rac1.

  3. novel roles for actin-depolymerizing factor (show DSTN Antibodies) and cofilin-1 in regulating the remodeling and permeability of epithelial junctions

  4. reelin (show RELN Antibodies) and cofilin cooperate in controlling cytoskeletal dynamics during neuronal migration.

  5. The data of this study identify overlapping functions for ADF (show TXN Antibodies) and n-cofilin in presynaptic physiology and vesicle in mice. trafficking.

  6. Actin depolymerizing factor/cofilin double mutant mice exhibited hyperlocomotion, impulsivity, and impaired working memory. Hyperlocomotion and impulsive behavior were reversed by methylphenidate.

  7. On the basal side of the neural plate, loss of CFL1 has the opposite effect on myosin: excess F-actin and myosin accumulate and the ectopic myosin light chain is phosphorylated.

  8. LIMK1 (show LIMK1 Antibodies) and Cofilin phosphorylation depends on PKA and is essential for mouse sperm acrosomal exocytosis

  9. prion protein is a co-receptor mediating neuronal cofilin-actin rod formation induced by beta-amyloid and proinflammatory cytokines

  10. The principal role of cofilin in lamellipodia at steady state is to break down F-actin, control filament turnover, and regulate the rate of retrograde flow.

Pig (Porcine) Cofilin 1 (Non-Muscle) (CFL1) interaction partners

  1. In vitro, formation of cofilin oligomers was drastically reduced after phosphorylation by LIMK2 (show LIMK2 Antibodies).

  2. glucose increases p-cofilin by phosphorylating LIMK1 through activation of Rho/Rho kinase, probably due to diacylglycerol-sensitive PKC activation resulting from increased glucose influx

  3. Cofilin is necessary for maintaining the osmotic responsiveness of the cytoskeleton in tubular cells, and the Rho/ROCK/LIMK-mediated cofilin phosphorylation is a key mechanism in the hyperosmotic stress-induced F-actin increase.

Cofilin 1 (Non-Muscle) (CFL1) Antigen Profile

Protein Summary

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Gene names and symbols associated with CFL1

  • cofilin 1 (non-muscle) (cfl1-a) antibody
  • cofilin 1 (non-muscle) (cfl1) antibody
  • cofilin 1 (non-muscle) (CFL1) antibody
  • twinstar (tsr) antibody
  • Cof1p (COF1) antibody
  • cofilin (TSTA_042790) antibody
  • cofilin 1 (non-muscle) (Cfl1) antibody
  • cofilin 1 (non-muscle)-like (LOC100341589) antibody
  • cofilin 1, non-muscle (Cfl1) antibody
  • COFILIN protein (COFILIN) antibody
  • Contrafreeloading (CFL) antibody
  • 12/8 antibody
  • AA959946 antibody
  • Adf antibody
  • ADF/cofilin antibody
  • Cadf antibody
  • cb86 antibody
  • CFL antibody
  • CFL1 antibody
  • CG4254 antibody
  • Cof antibody
  • cofilin antibody
  • cofilin/actin depolymerizing factor homolog antibody
  • cofilin/ADF antibody
  • D-cof antibody
  • D61 antibody
  • Dmel\\CG4254 antibody
  • l(2)03101 antibody
  • l(2)k03101 antibody
  • l(2)k05633 antibody
  • l(2)k13409 antibody
  • ntf antibody
  • sb:cb86 antibody
  • T8 antibody
  • Tsr antibody
  • wu:fb18a04 antibody
  • wu:fk77b03 antibody
  • xac1 antibody
  • xac2 antibody
  • zgc:56501 antibody

Protein level used designations for CFL1

ADF/cofilin-1 , cofilin-1-A , ADF/cofilin , cofilin-1 , non-muscle cofilin 1 , cofilin 1 (non-muscle) , ADFcofilin , CG4254-PA , Cofilin/actin depolymerizing factor-like , DCofilin , actin-depolymerizing factor , cofilin , no terminal filament , tsr-PA , twin star , Cof1p , 18 kDa phosphoprotein , cofilin, non-muscle isoform , p18

GENE ID SPECIES
379258 Xenopus laevis
407855 Xenopus (Silurana) tropicalis
406738 Danio rerio
745772 Pan troglodytes
37841 Drosophila melanogaster
850676 Saccharomyces cerevisiae S288c
8104756 Talaromyces stipitatus ATCC 10500
1072 Homo sapiens
476022 Canis lupus familiaris
534553 Bos taurus
100732287 Cavia porcellus
494432 Ovis aries
100341589 Oryctolagus cuniculus
12631 Mus musculus
29271 Rattus norvegicus
445532 Sus scrofa
100309654 Gallus gallus
Selected quality suppliers for anti-Cofilin 1 (Non-Muscle) (CFL1) Antibodies
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