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anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) Antibodies

CC2D1A encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. Additionally we are shipping Coiled-Coil and C2 Domain Containing 1A Kits (23) and Coiled-Coil and C2 Domain Containing 1A Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CC2D1A 54862 Q6P1N0
CC2D1A 212139 Q8K1A6
CC2D1A 288908 Q66HA5
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Top anti-Coiled-Coil and C2 Domain Containing 1A Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB CC2D1A Antibody (N-term) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the CC2D1A antibody detected the CC2D1A protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB CC2D1A Antibody (N-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CC2D1A antibody detected the CC2D1A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB Western Blot analysis of CC2D1A expression in transfected 293T cell line by CC2D1A MaxPab polyclonal antibody.Lane 1: CC2D1A transfected lysate(104.61 KDa).Lane 2: Non-transfected lysate. CC2D1A MaxPab polyclonal antibody. Western Blot analysis of CC2D1A expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IP, WB CC2D1A MaxPab rabbit polyclonal antibody. Western Blot analysis of CC2D1A expression in human liver. Immunoprecipitation of CC2D1A transfected lysate using anti-CC2D1A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with CC2D1A MaxPab rabbit polyclonal antibody (D01) . 100 μL Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated WB CC2D1A MaxPab rabbit polyclonal antibody. Western Blot analysis of CC2D1A expression in human liver. Western Blot analysis of CC2D1A expression in transfected 293T cell line by CC2D1A MaxPab polyclonal antibody.Lane 1: CC2D1A transfected lysate(104.10 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

CC2D1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-Coiled-Coil and C2 Domain Containing 1A Antibodies

  1. Human Polyclonal CC2D1A Primary Antibody for EIA, WB - ABIN951079 : Zhao, Li, Chen: CC2D1A, a DM14 and C2 domain protein, activates NF-kappaB through the canonical pathway. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN951079

  2. Human Polyclonal CC2D1A Primary Antibody for IF, IHC (p) - ABIN527223 : Nakamura, Arai, Fujita: Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement. in The Journal of cell biology 2009 (PubMed)

More Antibodies against Coiled-Coil and C2 Domain Containing 1A Interaction Partners

Human Coiled-Coil and C2 Domain Containing 1A (CC2D1A) interaction partners

  1. Aki1 was expressed in human diffuse malignant mesothelioma specimens. Expression correlated with phosphorylated CREB1 (show CREB1 Antibodies). Aki1 regulates CREB (show CREB1 Antibodies) by modulating protein kinase A activity. The Aki1-CREB (show CREB1 Antibodies) axis plays an important role in DMM (show COL2A1 Antibodies) pathogenesis.

  2. Null mutations in CC2D1A consistently cause a variable spectrum of presentations including ID, ASD (show ARSD Antibodies), and seizures. CC2D1A regulates NF-kappaB (show NFKB1 Antibodies) signaling.

  3. All of the pancreatic cancer cell lines expressed Aki1. Silencing of Aki1 in Panc1 cells reduced the phosphorylation of Akt (show AKT1 Antibodies) and increased the phosphorylation of cleaved PARP (show COL11A2 Antibodies).

  4. Non-genomic downregulation of 5-HT1A receptor (show HTR1A Antibodies) by 17betaestradiol does not involve NUDR (show DEAF1 Antibodies) and Freud-1 proteins.

  5. TBK1 (show TBK1 Antibodies)-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I (show DDX58 Antibodies)-like receptors to antiviral immunity

  6. CHMP4B (show CHMP4A Antibodies) interacts directly with CC2D1A and CC2D1B (show CC2D1B Antibodies) with nanomolar affinity by forming a 1:1 complex.

  7. CC2D1A interaction with CHMP4B (show CHMP4A Antibodies)/4A blocks HIV-1 budding.

  8. Results suggest the involvement of CC2D1A and CC2D2A in mental retardation in the Han Chinese population, and some specific haplotypes may be susceptible or protective.

  9. Reductions in Freud-1 expression in prefrontal cortex may be associated with early onset of major depressive disorder.

  10. Data suggest that the anti-tumor activity of NF-kappaB (show NFKB1 Antibodies) inhibitors is associated with p53 (show TP53 Antibodies)-mediated activation of autophagy.

Mouse (Murine) Coiled-Coil and C2 Domain Containing 1A (CC2D1A) interaction partners

  1. CC2D1A and CC2D1B (show CC2D1B Antibodies) role and function in the endocytic pathway and Notch (show NOTCH1 Antibodies) signalling.

  2. TBK1 (show TBK1 Antibodies)-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I (show DDX58 Antibodies)-like receptors to antiviral immunity

  3. Cc2d1a is required for mouse survival and performs essential function in controlling functional maturation of synapses.

  4. Freud-1, is involved in the compensatory mechanisms that modulate the functional state of brain serotonin system, although it is not the only factor for 5-HT(1A (show HTR1A Antibodies)) receptor transcriptional regulation.

  5. Freud-1 has a key role in regulating DRD2 (show DRD2 Antibodies) expression

  6. Paper describes a function of Cc2d1a/Cc2d1b (show CC2D1B Antibodies) and its Drosophila homologue l(2)gd in D.melanogaster in Notch (show NOTCH1 Antibodies) trafficking.

  7. Novel calcium-regulated repressor that negatively regulates basal 5-HT1A receptor expression.

Coiled-Coil and C2 Domain Containing 1A (CC2D1A) Antigen Profile

Protein Summary

This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.

Gene names and symbols associated with CC2D1A

  • coiled-coil and C2 domain containing 1A (CC2D1A) antibody
  • coiled-coil and C2 domain containing 1A (cc2d1a) antibody
  • coiled-coil and C2 domain containing 1A (Cc2d1a) antibody
  • BC016188 antibody
  • Freud-1 antibody
  • Freud-1/Aki1 antibody
  • MRT3 antibody
  • RGD1306108 antibody
  • Tape antibody

Protein level used designations for CC2D1A

coiled-coil and C2 domain containing 1A , coiled-coil and C2 domain-containing protein 1A , coiled-coil and C2 domain-containing protein 1A-like , Akt kinase-interacting protein 1 , FRE under dual repression-binding protein 1 , five prime repressor element under dual repression-binding protein 1 , five repressor element under dual repression-binding protein 1 , mental retardation, nonsyndromic, autosomal recessive, 3 , putative NF-kappa-B-activating protein 023N , putative NFkB activating protein , 5-HT1A receptor , five' repressor element under dual repression binding protein 1 , freud-1

GENE ID SPECIES
468744 Pan troglodytes
484911 Canis lupus familiaris
513078 Bos taurus
718483 Macaca mulatta
100020918 Monodelphis domestica
100145460 Xenopus (Silurana) tropicalis
100482182 Ailuropoda melanoleuca
100603711 Nomascus leucogenys
54862 Homo sapiens
212139 Mus musculus
288908 Rattus norvegicus
100712639 Cavia porcellus
101119902 Ovis aries
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