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anti-Collagen, Type VI, alpha 3 (COL6a3) Antibodies

COL6a3 encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. Additionally we are shipping COL6a3 Kits (18) and COL6a3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL6a3 12835  
Anti-Rat COL6a3 COL6a3 367313  
COL6a3 1293 P12111
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Top anti-COL6a3 Antibodies at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated   100 μg Log in to see 9 to 16 Days
$574.35
Details
Mouse Rabbit Un-conjugated   100 μg Log in to see 29 to 34 Days
$590.09
Details

COL6a3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,


Human , ,


More Antibodies against COL6a3 Interaction Partners

Mouse (Murine) Collagen, Type VI, alpha 3 (COL6a3) interaction partners

  1. Data show that the TFIID subunit (show TAF6 Antibodies) TAF4 (show TAF4 Antibodies) is essential to restrain the growth promoting properties of collagen 6A3 (Col6a3).

  2. mice lacking normal alpha3(VI) collagen chains display mild musculoskeletal phenotypes similar to mice deficient in the alpha1(VI) collagen alpha chain (show FCGRT Antibodies), suggesting that alpha3(VI) collagen does not elicit essential functions in normal growth and development

Human Collagen, Type VI, alpha 3 (COL6a3) interaction partners

  1. Data indicate that circulating plasma COL6A3 in colorectal cancer (CRC (show CALR Antibodies)) patients was upregulated significantly comparing with healthy peoples.

  2. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1 (show COL6A1 Antibodies), COL6A2 (show COL6A2 Antibodies), and COL6A3) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  3. Recessive mutations in the alpha3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia.

  4. Increased adipocyte COL6A3 expression associates with insulin (show INS Antibodies) resistance; COL6A3 mRNA associates with small adipocyte size

  5. The heterozygous c.3353A>C mutation in exon 8 of the COL6A3 gene is associated with the Bethlem myopathy with autosomal dominant inheritance.

  6. This study showed that COL6A3 expression appeared to be lowered in obesity, whereas diet- and surgery-induced weight loss increased COL6A3 expression.

  7. Mutations in each of the three collagen VI genes, COL6A1 (show COL6A1 Antibodies), COL6A2 (show COL6A2 Antibodies) and COL6A3, cause four types of muscle disorders: Ullrich congenital muscular dystrophy, Bethlem myopathy, limb-girdle muscular dystrophy, and autosomal recessive myosclerosis. (Review)

  8. Data indicate that the aberrantly methylated and expressed genes in cancer process including IRS1 (show IRS1 Antibodies) and collagen-related genes COL4A1 (show COL4A1 Antibodies), COL4A2 (show COL4a2 Antibodies) and COL6A3.

  9. Mutations in COL6A3 cause severe and mild phenotypes of Ullrich congenital muscular dystrophy.

  10. Haplotype analysis clearly suggested linkage of Ullrich muscular dystrophy to the COL6A1 (show COL6A1 Antibodies)/2 locus in two cases and to the COL6A3 loci in the third case. In the remaining nine patients, primary collagen VI involvement was excluded

COL6a3 Antigen Profile

Protein Summary

This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described.

Gene names and symbols associated with COL6a3

  • collagen, type VI, alpha 3 (COL6A3) antibody
  • collagen, type VI, alpha 3 (col6a3) antibody
  • collagen, type VI, alpha 3 (Col6a3) antibody
  • AI507288 antibody
  • Col6a-3 antibody
  • COL6A3 antibody
  • wu:fb06e12 antibody
  • wu:fs74g09 antibody

Protein level used designations for COL6a3

collagen alpha-3(VI) chain , type VI collagen alpha 3 chain , alpha 3 type VI collagen , collagen, type VI, alpha 3 , collagen alpha-3(VI) chain-like , collagen alpha 3 chain type VI , collagen alpha3(VI) , procollagen, type VI, alpha 3 , type VI collagen alpha 3 subunit , collagen VI, alpha-3 polypeptide , alpha-3 collagen type VI , collagen type VI alpha 3

GENE ID SPECIES
403582 Canis lupus familiaris
460045 Pan troglodytes
530657 Bos taurus
556874 Danio rerio
694701 Macaca mulatta
100459849 Pongo abelii
100465530 Ailuropoda melanoleuca
12835 Mus musculus
367313 Rattus norvegicus
1293 Homo sapiens
396548 Gallus gallus
100101551 Sus scrofa
100716662 Cavia porcellus
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