Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CTH encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Additionally we are shipping CTH Kits (24) and CTH Proteins (18) and many more products for this protein.
Showing 10 out of 79 products:
Human Monoclonal CTH Primary Antibody for IHC (p), ELISA - ABIN560523
Siebert, Cantré, Eipel, Vollmar: H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of K(ATP) channels. in American journal of physiology. Gastrointestinal and liver physiology 2008
Show all 7 references for ABIN560523
Human Monoclonal CTH Primary Antibody for ELISA, WB - ABIN560522
dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. in Proceedings of the National Academy of Sciences of the United States of America 2009
Show all 4 references for ABIN560522
Dog (Canine) Polyclonal CTH Primary Antibody for IHC, WB - ABIN2782464
Yang, Cao, Wu, Wang: Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. in The Journal of biological chemistry 2004
Show all 2 references for ABIN2782464
Cow (Bovine) Polyclonal CTH Primary Antibody for WB - ABIN2782463
Moore, Malats, Rothman, Real, Kogevinas, Karami, García-Closas, Silverman, Chanock, Welch, Tardón, Serra, Carrato, Dosemeci, García-Closas: Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer. in International journal of cancer. Journal international du cancer 2007
Show all 2 references for ABIN2782463
ur findings suggest that these two families of amines inhibit cystathionine-gamma-lyase (CSE) to varying extents, which directly results in altered levels of intracellular HCY and consequent changes in Human vascular smooth muscle cells proliferation.
Lipopolysaccharide increases the expression of CSE in human macrophages, increasing H2S synthesis, via ERK (show EPHB2 Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway.
Nox4 (show NOX4 Antibodies) is a positive transcriptional regulator of cystathionine-gamma-lyase in endothelial cells.
The expression of CSE was positively correlated with the severity of gastric ulcer
Our study demonstrates that CSE/H2S system is regulated by miR (show MLXIP Antibodies)-216a, and regulates ABCA1 (show ABCA1 Antibodies)-mediated cholesterol efflux and cholesterol levels through the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway.
Collectively, our findings indicate that radiation could promote HCC (show FAM126A Antibodies) cell invasion through EMT (show ITK Antibodies) mediated by endogenous H2S/CSE signaling via the p38MAPK (show MAPK14 Antibodies) pathway.
3-Mercaptopyruvate sulphurtransferase and not cystathionine gamma-lyase is the primary regulator of coronary artery hydrogen sulfide (show SQRDL Antibodies) production and function.
An increase of placental mRNA levels in the pre-eclampsia group was observed for methionine synthase (show MTR Antibodies) and cystathionine gamma-lyase.
GPBAR1 plays a role in secondary bile acid induced vasodilation via reglation of cystathionine gamma-lyase. The GPBAR1/CSE pathway might contribute to endothelial dysfunction and hyperdynamic circulation in liver cirrhosis.
The miR (show MLXIP Antibodies)-30 family are potentially important regulators of cystathionine gamma-lyase gene expression.
Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.
lung MPO activity increased following induction of sepsis with CLP while siRNA treatment significantly reduced MPO activity. Liver and lung cytokine and chemokine levels in CLP-induced sepsis reduced following treatment with siRNA. These findings show a crucial pro-inflammatory role for H2S synthesized by CSE in macrophages in sepsis and suggest CSE gene silencing with siRNA as a potential therapeutic approach for this co
H2S augmented the S-sulfhydration of the rate-limiting gluconeogenic enzymes and PGC-1alpha (show PPARGC1A Antibodies) and increased their activities, which were lower in untreated : To investigate the regulation of hepatic glucose production by cystathionine gamma-lyase KO hepatocytes
Endogenous cystathionine gamma-lyase/Hydrogen sulfide (show SQRDL Antibodies) regulates ischaemic vascular remodelling mediated during hind limb ischaemia through NO-dependent monocyte recruitment
The results of this study suggest that CSE is not critically involved in chronic pain signaling in mice and that sources different from CSE mediate the pain relevant effects of H2S.
CSE-H2S increased PPARgamma (show PPARG Antibodies) activity by direct sulfhydration at the C139 site, thereby changing glucose into triglyceride storage in adipocytes.
Therefore, our data suggest that DNA hypermethylation of CpG rich region in cse promoter might contribute to the decrease of cse transcription and H2S production in macrophages, and thus contribute to atherosclerosis development.
These data confirm a key role for the H2S-generating enzymes Cbs (show CBS Antibodies) and Cth in pulmonary vascular development and homeostasis and in lung alveolarization.
CTH inhibition did not affect the oviductal embryo transport, although delay of early embryo development was observed.
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
, cystathionase (cystathionine gamma-lyase)
, cysteine desulfhydrase
, cysteine-protein sulfhydrase
, homoserine deaminase
, homoserine dehydratase
, CTL target antigen
, probasin-related antigen