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anti-Cystathionine-beta-Synthase (CBS) Antibodies

The protein encoded by CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. Additionally we are shipping Cystathionine-beta-Synthase Proteins (17) and Cystathionine-beta-Synthase Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBS 24250 P32232
CBS 12411 Q91WT9
CBS 875 P35520
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Top anti-Cystathionine-beta-Synthase Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of CBS Antibody (Center) (ABIN390947) in mouse kidney tissue lysates (35 µg/lane). CBS (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with CBS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using CBS antibody. 100 μL Log in to see 9 Days
$302.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Detection limit for recombinant GST tagged CBS is approximately 0.03ng/ml as a capture antibody. Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), IP, RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to CBS on formalin-fixed paraffin-embedded human hepatocellular carcinoma. [antibody concentration 3 ug/ml] CBS monoclonal antibody (M01), clone 3E1 Western Blot analysis of CBS expression in HeLa . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details

CBS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)
,
,
Mouse (Murine)
,
,
Human , , , ,
,
,
, , , , ,

Top referenced anti-Cystathionine-beta-Synthase Antibodies

  1. Human Monoclonal CBS Primary Antibody for IHC (p), IP - ABIN560206 : Schicho, Krueger, Zeller, Von Weyhern, Frieling, Kimura, Ishii, De Giorgio, Campi, Schemann: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. in Gastroenterology 2006 (PubMed)
    Show all 37 references for ABIN560206

  2. Chicken Polyclonal CBS Primary Antibody for IHC, WB - ABIN2782348 : Urreizti, Asteggiano, Bermudez, Córdoba, Szlago, Szlago, Grosso, de Kremer, Vilarinho, DAlmeida, Martínez-Pardo, Peña-Quintana, Dalmau, Bernal, Briceño, Couce, Rodés, Vilaseca, Balcells, Grinberg: The p.T191M mutation of the CBS gene is highly prevalent among homocystinuric patients from Spain, Portugal and South America. in Journal of human genetics 2006 (PubMed)
    Show all 6 references for ABIN2782348

  3. Human Polyclonal CBS Primary Antibody for FACS, IF - ABIN1881141 : Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells. in The Journal of biological chemistry 2012 (PubMed)
    Show all 2 references for ABIN1881141

  4. Human Monoclonal CBS Primary Antibody for IF, IHC (p) - ABIN514088 : Majtan, Freeman, Smith, Burstyn, Kraus: Purification and characterization of cystathionine ?-synthase bearing a cobalt protoporphyrin. in Archives of biochemistry and biophysics 2011 (PubMed)

  5. Mouse (Murine) Polyclonal CBS Primary Antibody for IHC, WB - ABIN3021959 : Robert, Vialard, Thiery, Toyama, Sinet, Janel, London: Expression of the cystathionine beta synthase (CBS) gene during mouse development and immunolocalization in adult brain. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003 (PubMed)

  6. Human Polyclonal CBS Primary Antibody for FACS, IF - ABIN390947 : Ravel, Chantot-Bastaraud, Chalmey, Barreiro, Aknin-Seifer, Pfeffer, Berthaut, Mathieu, Mandelbaum, Siffroi, McElreavey, Bashamboo: Lack of association between genetic polymorphisms in enzymes associated with folate metabolism and unexplained reduced sperm counts. in PLoS ONE 2009 (PubMed)

More Antibodies against Cystathionine-beta-Synthase Interaction Partners

Chimpanzee Cystathionine-beta-Synthase (CBS) interaction partners

Mouse (Murine) Cystathionine-beta-Synthase (CBS) interaction partners

  1. These data confirm a key role for the H2S-generating enzymes Cbs and Cth (show CTH Antibodies) in pulmonary vascular development and homeostasis and in lung alveolarization.

  2. genetic deficiency results in reduced Tet1 (show TET1 Antibodies) and Tet2 (show TET2 Antibodies) expression, which leads to hypermethylation of Foxp3 (show FOXP3 Antibodies), and impairment of Treg cell differentiation and immune homeostasis.

  3. Elevated homocytsteine levels in the CBS-/+ mouse skeletal muscles caused diminished anti-oxidant capacity and contributed to enhanced total protein as well as PGC-1alpha (show PPARGC1A Antibodies) specific nitrotyrosylation after ischemia.

  4. CBS disruption causes embryo retention and developmental delay in the mouse oviduct.

  5. CBS is present in adrenocortical cells and accounts for H2S generation in adrenal glands. CBS is critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.

  6. Elevating endogenous H2S via CBS over-expression in immortalized microglia not only reduced the expression of pro-inflammatory M1 genes, but also enhanced the anti-inflammatory M2 marker IL-10 (show IL10 Antibodies) production.

  7. Cbs protein expression is upregulated in brain cortex following traumatic brain injury.

  8. Brain of mice heterozygous for Cbs displays overexpression of DYR (show DHFR Antibodies) kinase and SAH (show ACSM3 Antibodies) hydrolase.

  9. These findings set the stage to investigate the role of CBS and the transsulfuration pathway in the generation of GSH in mouse retina.

  10. Hydrogen sulfide (show SQRDL Antibodies) in the cortex and hippocampus exhibited dynamic changes after brain injury, in parallel with CBS mRNA and protein expression

Human Cystathionine-beta-Synthase (CBS) interaction partners

  1. In Asian populations, the investigated polymorphisms mapping at TCN2 (show TCN2 Antibodies) and CBS genes did not provide any evidence of association with cleft lip/cleftpalate.

  2. Study found a novel association of CD2AP (show Cd2ap Antibodies) with plasma homocysteine in participants with African ancestry and found a new variant in the candidate gene CBS associated with homocysteine

  3. Cystathionine-beta-synthase carriers tend to have a higher serum total homocysteine level in the presence of folate deficiency than non-carriers

  4. CBS is involved in regulating lipid metabolism in ovarian cancer cells.

  5. In addition to being a potential source of superoxide radical, CBS constitutes a previously unrecognized source of NO(*)and peroxynitrite.

  6. The H2S-producing enzyme cystathionine beta-synthase (CBS), sustaining cellular bioenergetics in colorectal cancer cells, plays a role in the interplay between gasotransmitters. (Review)

  7. CBS expression is elevated in breast cancer.

  8. AdoMet (show MAT1A Antibodies) binding significantly enhances CBS inhibition by carbon monoxide.

  9. Cystathionine beta-synthase-derived hydrogen sulfide (show SQRDL Antibodies) is involved in human malignant hyperthermia.

  10. Propose that a distinct group of heme-responsive CBS mutations may exist in homocystinuria, which can be rescued using heme arginate.

Cystathionine-beta-Synthase (CBS) Antigen Profile

Protein Summary

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CBS

  • cystathionine-beta-synthase (cbs-a) antibody
  • cystathionine-beta-synthase (cbs) antibody
  • cystathionine beta-synthase (Cbs) antibody
  • cystathionine-beta-synthase (CBS) antibody
  • cystathionine beta-synthase (CNA06170) antibody
  • cystathionine beta-synthase (Tb11.02.5400) antibody
  • cystathionine beta-synthase CBS (cbs) antibody
  • cystathionine beta-synthase (cbs) antibody
  • cystathionine beta-synthase (cysB) antibody
  • cystathionine beta synthase (Cbs) antibody
  • cystathionine-beta-synthase (cbs-b) antibody
  • cystathionine-beta-synthase b (cbsb) antibody
  • AI047524 antibody
  • AI303044 antibody
  • cb442 antibody
  • cbs antibody
  • DDBDRAFT_0189727 antibody
  • DDBDRAFT_0191292 antibody
  • DDB_0189727 antibody
  • DDB_0191292 antibody
  • GB12529 antibody
  • HIP4 antibody
  • wu:fb37g05 antibody
  • wu:fm61c07 antibody
  • wu:fq06c06 antibody
  • zgc:113704 antibody

Protein level used designations for CBS

cystathionine-beta-synthase , cystathionine beta-synthase , cystathionine beta-synthase CBS , beta-thionase , hemoprotein H-450 , serine sulfhydrase , methylcysteine synthase

GENE ID SPECIES
380308 Xenopus laevis
493533 Xenopus (Silurana) tropicalis
551341 Apis mellifera
736626 Pan troglodytes
3253577 Cryptococcus neoformans var. neoformans JEC21
3665875 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4551426 Mycobacterium ulcerans Agy99
6228672 Mycobacterium marinum M
7006755 Rhodospirillum centenum SW
7705918 Gemmatimonas aurantiaca T-27
7712188 Rhodococcus erythropolis PR4
7746532 Rhodococcus opacus B4
8616308 Dictyostelium discoideum AX4
100136726 Oncorhynchus mykiss
100635325 Amphimedon queenslandica
24250 Rattus norvegicus
12411 Mus musculus
446655 Xenopus laevis
418545 Gallus gallus
875 Homo sapiens
611071 Canis lupus familiaris
514525 Bos taurus
100008766 Oryctolagus cuniculus
266987 Danio rerio
Selected quality suppliers for anti-Cystathionine-beta-Synthase (CBS) Antibodies
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