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putative cysteinyl leukotriene receptor [RGD, Feb 2006].. Additionally we are shipping CasLTR2 Antibodies (61) and CasLTR2 Kits (34) and many more products for this protein.
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findings implicate CYSLTR2 as a uveal melanoma oncogene (show RAB1A Proteins) and highlight the critical role of Galphaq (show GNAQ Proteins) signaling in uveal melanoma pathogenesis
CysLT2 receptors were expressed in lung specimens isolated from asthma subjects. Activation of CysLT2 receptors may contribute to antigen-induced bronchoconstriction in certain asthma population.
CysLTR-1 (show CYSLTR1 Proteins) and CysLTR-2 are highly expressed in the adenoid tissues from children with AH, suggesting that leukotrienes are involved in the pathogenesis of AH.
Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.
ATRA treatment induces CysLT(2)R mRNA and protein expression in colon cancer cell lines
CysLT2 receptor plays a primary role in the vascular responses in the upper respiratory tract.
There is a protective role against tumor progression for CysLT(2)R and that it highlights new possibilities to regulate the CysLT(2)R.
The synthesis of cys (show DNAJC5 Proteins)-LTs from LTA (show LTA Proteins)(4) by endothelial cells is directly associated with the activation of the CysLT(2) receptor in a typical autocrine fashion.
Cysteinyl leukotriene receptor 2 gene polymorphism -1220 A/C is not associated with atopic dermatitis or psoriasis vulgaris in Japanese patients.
upon ligand activation, CysLT(1 (show CYSLTR1 Proteins))R is tyrosine-phosphorylated and released from heterodimers with CysLT(2)R and, subsequently, internalizes from the plasma membrane to the nuclear membrane in a clathrin-, arrestin-3 (show ARRB2 Proteins)-, and Rab-5 (show RAB5A Proteins)-dependent manner
The CysLT(1 (show CYSLTR1 Proteins)) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils
LTC4 activates mouse platelets exclusively through CysLT2R. LTC4/CysLT2R signaling required an autocrine ADP-mediated response through P2Y12 (show P2RY12 Proteins) receptors.
CysLT1R (show CYSLTR1 Proteins), CysLT2R and GPR17 (show GPR17 Proteins) might be involved in the MPTP (show PTPN2 Proteins)-induced Parkinson disease damage in mice.
CysLT2R negatively regulates the development of cys (show DNAJC5 Proteins)-LT-dependent T helper cell (Th)2 pulmonary inflammation by inhibiting both CysLT1R (show CYSLTR1 Proteins) signaling and house dust mite-induced LTC4S (show LTC4S Proteins)-dependent cell surface expression of CysLT1R (show CYSLTR1 Proteins) on dendritic cells.
These findings establish a role for eosinophil-derived cysteinyl leukotriene and the CysLT(2)R in the hyperkeratosis and fibrosis of allergic skin inflammation.
Results implicate the CysLT(2)R in the progression of ischemic retinopathy.
These results suggest that a lack of neuronal expression of CysLTR (show CYSLTR1 Proteins) in the murine colonic myenteric plexus attenuates colitis disease progression.
findings show that CysLT1 receptor (show CYSLTR1 Proteins) attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death
CysLT2 receptors interact with CysLT1 (show CYSLTR1 Proteins) receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.
In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase (show ALOX5 Proteins)) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase (show LTC4S Proteins)) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 (show PTGR1 Proteins) level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows.
putative cysteinyl leukotriene receptor
cysteinyl leukotriene receptor 2
, G protein-coupled receptor
, G-protein coupled receptor GPCR21
, G-protein coupled receptor HG57
, cysteinyl leukotriene CysLT2 receptor