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Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Proteins (CYP21A2)

CYP21A2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Antibodies (75) and Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP21A2 13079 P03940
CYP21A2 24298  
CYP21A2 1589 P08686
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Top Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
Yeast Rat His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,393.50
Details

CYP21A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Rat (Rattus) ,
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Human , ,
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More Proteins for Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) Interaction Partners

Pig (Porcine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. CYP21 gene polymorphisms were analyzed in association with litter size.

Mouse (Murine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

Human Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. In current study, molecular testing of 21 patients with classic form of Congenital adrenal hyperplasia identified eight mutations of the CYP21A2 gene.

  2. The results suggest that the A>G variation in the Z promoter is involved in misregulating the transcriptional activity of the CYP21A2 gene.

  3. Data suggest 3 siblings with nonclassical, congenital adrenal hyperplasia exhibit rare mutation in CYP21A2; siblings are heterozygotes for maternal 30 kb deletion and exhibit a second, rare point mutation (c.1097G>A, p.R366H) in exon 8. [CASE REPORT]

  4. Novel p.Leu129Pro and p.Ser165Pro CYP21A2 gene mutations in Serbian patients with congenital adrenal hyperplasia.

  5. The main conclusion from a mutation-structure-activity study is that the severity of the congenital adrenal hyperplasia clinical manifestations can be directly correlated with the degree of mutation-induced damage in terms of protein fold stability and active site changes in the structural model of Cytochrome P450 21A2.

  6. Increased allelic frequency for the CYP21A2 p.Asn493Ser polymorphism is observed in girls with premature adrenarche.

  7. Prevalence of P30L, P453S, and V281L mutations of CYP21A2 gene is increased in patients with adrenocortical tumors.

  8. Mutations of CYP21A2 gene is associated with 21-hydroxylase deficiency.

  9. This study aimed to design a reliable and rational approach for identifying mutations in the CYP21A2 gene and to characterize the molecular basis of 21-Hydroxylase deficiency in 30 Chinese patients.

  10. mutations of the CYP21A2 gene may have a role in nonclassical congenital adrenal hyperplasia

Cow (Bovine) Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) interaction partners

  1. The mRNA expression of P450Arom (show CYP19A1 Proteins) was detected using RT-PCR analysis in both hypothalamic and cortical primary cell cultures. P450Arom (show CYP19A1 Proteins) was identified in both neurons and astrocytes

Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene\; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP21A2

  • cytochrome P450, family 21, subfamily A, polypepide 2 (CYP21A2)
  • cytochrome P450, family 21, subfamily a, polypeptide 1 (Cyp21a1)
  • cytochrome P450, family 21, subfamily A, polypeptide 2 (CYP21A2)
  • cytochrome P450, subfamily XXI (steroid 21-hydroxylase) (CYP21)
  • cytochrome P450c21 (CYP21A2)
  • steroid 21-hydroxylase-like (LOC101094596)
  • 21-OH protein
  • 21-OHase protein
  • 21OH protein
  • 21OHA protein
  • 21OHB protein
  • CA21H protein
  • CAH1 protein
  • CPS1 protein
  • Cyp21 protein
  • Cyp21-ps1 protein
  • CYP21A protein
  • Cyp21a2-ps protein
  • Cyp21a2ps protein
  • CYP21B protein
  • CYP21OH-A protein
  • Oh21-1 protein
  • Oh21-2 protein
  • P450c21B protein

Protein level used designations for CYP21A2

21-OHase , FK506 binding protein like , cytochrome P-450c21 , cytochrome P450 21 , cytochrome P450 21-hydroxylase , cytochrome P450 XXI , cytochrome P450-C21 , steroid 21-hydroxylase , 21-hydroxylase , cytochrome P-450 , cytochrome P450 hydroxylase A , cytochrome P450, 21, pseudogene , cytochrome P450, 21, steroid 21 hydroxylase , cytochrome P450, family 21, subfamily a, polypeptide 2, pseudogene , steroid 21 hydroxylase , Cytochrome P450 subfamily XXI (steroid 21-hydroxylase) , P-450c21 , P450-C21 , cytochrome P450 21 steroid 21 hydroxylase , cytochrome P450, subfamily 21A, polypeptide 1 , cytochrome P450, subfamily XXI (steroid 21-hydroxylase) , cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2 , cytochrome P450-C21B , steroid 21-monooxygenase , cytochrome P450, family 21 , cytochrome P450, family 21, subfamily A , Cytochrome P-450c21 , Cytochrome P450 21 , Cytochrome P450 XXI , Cytochrome P450-C21

GENE ID SPECIES
403337 Sus scrofa
13079 Mus musculus
24298 Rattus norvegicus
1589 Homo sapiens
282425 Bos taurus
281741 Bos taurus
415124 Canis lupus familiaris
101094596 Felis catus
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