anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) Antibodies

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. Additionally we are shipping CYFIP1 Proteins (4) and CYFIP1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYFIP1 23191 Q7L576
CYFIP1 20430 Q7TMB8
CYFIP1 308666  
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Top anti-CYFIP1 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYFIP1 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$221.76
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: CYFIP1 Antibody [NBP2-16060] - Sample (30 ug of whole cell lysate) A: HeLa 5% SDS PAGE gel, diluted at 1:1000. Western Blot: CYFIP1 Antibody [NBP2-16060] - Sample (30 ug of whole cell lysate) A: BCL-1 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western blot analysis of CYFIP1 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Bat Goat Un-conjugated ELISA   100 μg Log in to see 7 to 9 Days
$507.83
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$278.25
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using CYFIP1 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IP, WB Western Blot: CYFIP1 Antibody [NBP1-50028] - Detection of Human CYFIP1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CYFIP1 antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. CYFIP1 was also immunoprecipitated by rabbit anti-CYFIP1 antibody BL10812, which recognizes an upstream epitope. For blotting immunoprecipitated CYFIP1, the ReliaBLOT. Reagents and Procedures were used. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$375.83
Details

CYFIP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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, , , , ,
Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-CYFIP1 Antibodies

  1. Human Polyclonal CYFIP1 Primary Antibody for ELISA - ABIN4265993 : Silva, Ezhkova, Silva, Heart, Castillo, Campos, Castro, Bonilla, Cordon-Cardo, Muthuswamy, Powers, Fuchs, Hannon: Cyfip1 is a putative invasion suppressor in epithelial cancers. in Cell 2009 (PubMed)

More Antibodies against CYFIP1 Interaction Partners

Human Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) interaction partners

  1. The studies suggest that MNK (show ATP7A Antibodies)-eiF4E (show EIF4E Antibodies) axis controls the translation of specific mRNAs in cancer metastasis and neuronal synaptic plasticity by a novel mechanism involving the regulation of the translational repressor, CYFIP1. (Review)

  2. rs4778298, a common variant at CYFIP1 is associated with inter-individual variation in surface area across the left supramarginal gyrus.

  3. we show that stapled peptides targeting the interface between NCKAP1 (show NCKAP1 Antibodies) and CYFIP1 destabilize the WASF3 (show WASF3 Antibodies) complex... thereby suppressing invasion and metastasis of breast cancer cells.

  4. Both mRNA and protein expression levels of Cyfip1 were significantly lower in ALL patients.

  5. Reduced CYFIP1 in human neural progenitors results in dysregulation of schizophrenia and epilepsy gene networks.

  6. Hippocampal synapses with reduced Cyfip1 are larger and release neurotransmitter more rapidly.

  7. Data confirm that CYFIP1 is upregulated in transformed lymphoblastoid cell lines and demonstrate its upregulation in the post-mortem brain from 15q11-13 duplication patients for the first time

  8. This study confirmed that CYFIP2 (show CYFIP2 Antibodies) were altered in postsynaptic density in patient with schizophrenia.

  9. An imbalance of specific isoforms of CYFIP1, an FMRP (show FMR1 Antibodies) interaction partner, and CAMK4 (show CAMK4 Antibodies), a transcriptional regulator of the FMRP (show FMR1 Antibodies) gene, modulates risk for autism spectrum disorders.

  10. Protein complexes containing CYFIP/Sra (show SRA1 Antibodies)/PIR121 (show CYFIP2 Antibodies) coordinate Arf1 (show ARF1 Antibodies) and Rac1 signalling during clathrin-AP-1 (show FOSB Antibodies)-coated carrier biogenesis at the trans-golgi network.

Mouse (Murine) Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) interaction partners

  1. In Cyfip1-deficient mice, parental origin determines the impairment of synaptic functions and behavior.

  2. Data suggest that MAP kinase (show MAPK1 Antibodies)-interacting kinases (Mnk1 (show MKNK1 Antibodies), Mnk2 (show MKNK2 Antibodies)) regulate cell migration/wound healing, expression of vimentin (show VIM Antibodies), stability of vimentin (show VIM Antibodies) protein, and binding of cytoplasmic eIF4E (eukaryotic translation initiation factor 4E (show EIF4E Antibodies)) and Cyfip1.

  3. CYFIP2 (show CYFIP2 Antibodies) is a key regulator of cocaine response in mammals and present a framework to use mouse substrains to identify previously unknown genes and alleles regulating behavior.

  4. This study demonistrated that CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation.

  5. haploinsufficiency of Cyfip1 mimics key aspects of the phenotype of Fmr1 (show FMR1 Antibodies) knockout mice and are consistent with the hypothesis that these effects are mediated by interaction of Cyfip1 and Fmrp (show FMR1 Antibodies) in regulating activity-dependent translation.

  6. Sra-1 and Nap1 are constitutive and essential components of a WAVE2- and Abi-1-containing complex linking Rac to site-directed actin assembly.

  7. The translational repression activity of FMRP (show FMR1 Antibodies) in the brain is mediated, at least in part, by CYFIP1.

CYFIP1 Antigen Profile

Protein Summary

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.

Gene names and symbols associated with CYFIP1

  • cytoplasmic FMR1 interacting protein 1 (CYFIP1) antibody
  • cytoplasmic FMR1 interacting protein 1 (cyfip1) antibody
  • cytoplasmic FMR1 interacting protein 1 (Cyfip1) antibody
  • CY antibody
  • CYFIP antibody
  • E030028J09Rik antibody
  • fb15a06 antibody
  • l(7)1Rl antibody
  • l7Rl1 antibody
  • l71Rl antibody
  • mKIAA0068 antibody
  • P140SRA-1 antibody
  • P140sra1 antibody
  • pl-1 antibody
  • Shyc antibody
  • Sra-1 antibody
  • Sra1 antibody
  • TUBGCP5 antibody
  • wu:fb15a06 antibody

Protein level used designations for CYFIP1

cytoplasmic FMR1 interacting protein 1 , cytoplasmic FMR1-interacting protein 1 , cytoplasmic FMRP interacting protein 1 , selective hybridizing clone , specifically Rac1-associated protein 1 , sra-1 , cytoplasmic FMR1-interacting protein 1 homolog

GENE ID SPECIES
418677 Gallus gallus
453278 Pan troglodytes
586128 Strongylocentrotus purpuratus
719579 Macaca mulatta
100411412 Callithrix jacchus
100459206 Pongo abelii
100564778 Anolis carolinensis
23191 Homo sapiens
479001 Canis lupus familiaris
100141021 Bos taurus
20430 Mus musculus
308666 Rattus norvegicus
336613 Danio rerio
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