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Diacylglycerol Kinase, epsilon 64kDa Proteins (DGKE)

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. Additionally we are shipping DGKE Antibodies (52) and DGKE Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DGKE 56077 Q9R1C6
DGKE 8526 P52429
Rat DGKE DGKE 497978  
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Top DGKE Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DGKE Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,

More Proteins for Diacylglycerol Kinase, epsilon 64kDa (DGKE) Interaction Partners

Mouse (Murine) Diacylglycerol Kinase, epsilon 64kDa (DGKE) interaction partners

  1. Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin (show HTT Proteins) toxicity.

  2. A regulatory role is suggested for DGK epsilon, COX-2, and catecholamine signaling during kindling epileptogenesis.

Human Diacylglycerol Kinase, epsilon 64kDa (DGKE) interaction partners

  1. Letter/Case Report: atypical haemolytic uraemic syndrome in a Japanese patient with DGKE genetic mutations.

  2. Report DGKE intronic mutations located beyond the exon-intron boundaries in familial hemolytic uremic syndrome.

  3. Data suggest that complement dysregulation influences the onset and disease severity in carriers of diacylglycerol kinase-epsilon mutations

  4. DGKE silencing in resting endothelial cells does not affect complement activation at their surface.

  5. Our study expands the clinical phenotypes associated with mutations in DGKE and challenges the benefits of complement blockade treatment in such patients

  6. DGKzeta (show DGKZ Proteins) localizes to the nucleus and is considered to regulate nuclear diacylglycerol signaling.[review]

  7. Fully activating high-density transfected muscarinic receptors (M1Rs) by oxotremorine-M (Oxo-M) leads to similar calcium, DAG, and PKC signals, but PIP2 is depleted.

  8. Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.

  9. Substrate specificity of DGKE is not a consequence of competition with hydrolysis of ATP.

  10. performed homozygosity mapping and whole exome sequencing in a Turkish consanguineous family and identified DGKE gene variants as the cause of a membranoproliferative-like glomerular microangiopathy

DGKE Protein Profile

Protein Summary

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis.

Gene names and symbols associated with DGKE

  • diacylglycerol kinase, epsilon 64kDa (dgke)
  • diacylglycerol kinase, epsilon 64kDa (DGKE)
  • diacylglycerol kinase, epsilon (AaeL_AAEL011709)
  • diacylglycerol kinase, epsilon (Dgke)
  • diacylglycerol kinase, epsilon 64kDa (Dgke)
  • C87606 protein
  • DAGK5 protein
  • DAGK6 protein
  • DGK protein
  • DGKE protein
  • MGC81643 protein
  • NPHS7 protein

Protein level used designations for DGKE

diacylglycerol kinase, epsilon 64kDa , diacylglycerol kinase epsilon , diacylglycerol kinase epsilon-like , diacylglycerol kinase, epsilon , DAG kinase epsilon , DGK-epsilon , diglyceride kinase epsilon

GENE ID SPECIES
447404 Xenopus laevis
468414 Pan troglodytes
712450 Macaca mulatta
770911 Gallus gallus
100056676 Equus caballus
100093422 Ornithorhynchus anatinus
100358196 Oryctolagus cuniculus
100395461 Callithrix jacchus
100481233 Ailuropoda melanoleuca
100489119 Xenopus (Silurana) tropicalis
100548310 Meleagris gallopavo
100567404 Anolis carolinensis
100594501 Nomascus leucogenys
5575244 Aedes aegypti
56077 Mus musculus
8526 Homo sapiens
497978 Rattus norvegicus
491102 Canis lupus familiaris
100312967 Sus scrofa
538147 Bos taurus
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