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Dishevelled, Dsh Homolog 3 (Drosophila) Proteins (DVL3)

DVL3 is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. Additionally we are shipping DVL3 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DVL3 13544 Q61062
DVL3 1857 Q92997
Rat DVL3 DVL3 303811  
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Top DVL3 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DVL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Interaction Partners

Xenopus laevis Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. Different Dvl (show DVL2 Proteins) proteins (Dvl1 (show DVL1 Proteins), Dvl2 (show DVL2 Proteins), Dvl3) and the composition of dishevelled (show DVL2 Proteins)-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 Proteins) signaling in Xenopus gastrulation.

  2. Data show that maternal Dvl2 and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin.

Mouse (Murine) Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. Dvl-2 (show DVL2 Proteins) and Dvl-3 have a widespread distribution in both the olfactory epithelium and olfactory bulb

  2. Dvl3 is important for IPMK (show IPMK Proteins) to access substrates and generate IP5, activating down-stream signaling.

  3. Dishevelled (show DVL2 Proteins)-KSRP (show KHSRP Proteins) complex operates in Wnt (show WNT2 Proteins) regulation of beta-catenin (show CTNNB1 Proteins), functioning post-transcriptionally upon CTNNB1 (show CTNNB1 Proteins) mRNA stability.

  4. Dvl2 (show DVL2 Proteins) and Dvl3 proteins were found to be localized to the apical side of the node cells, and their location was polarized to the posterior side of the cells before the posterior positioning of the basal body.

  5. As embryos reach blastocyst stage, Dishevelled 2 (show DVL2 Proteins) becomes increasingly associated with cell membrane in trophectoderm cells, while at E4.5, Dishevelled 3 is highly enriched in the cytoplasm of inner cell mass cells.

  6. The expression of Dishevelleds in mammalian cells provide an estimate of the relative cellular abundance of each Dvl (show DVL1 Proteins).

  7. G alpha o (show GNAO1 Proteins) mediates WNT (show WNT2 Proteins)-JNK (show MAPK8 Proteins) signaling through dishevelled 1 (show DVL1 Proteins) and 3, RhoA (show RHOA Proteins) family members, and MEKK 1 (show MAP2K1 Proteins) and 4 in mammalian cells

  8. Dvl1 (show DVL1 Proteins), Dvl2 (show DVL2 Proteins) and Dvl3 are functionally redundant in cardiac outflow tract, cochlea, and neural tube development.

Human Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. we demonstrate that normally ALFY attenuates the canonical Wnt (show WNT2 Proteins) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 and not of Dvl1 (show DVL1 Proteins) or Dvl2 (show DVL2 Proteins).

  2. All variants in DVL3 result in a -1 frameshift, indicating that these highly specific alterations might be a common cause of dominant Robinow syndrome.

  3. data suggest that miR (show MLXIP Proteins)-204-5p regulates adipogenesis by controlling DVL3 expression and subsequently inhibiting the activation of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.

  4. findings confirm that p38 (show CRK Proteins) and PAX2 (show PAX2 Proteins) are important for the Dvl-3 induced upregulation of p120ctn (show CTNND1 Proteins)

  5. Tumors that responded to IGFIR inhibition contain relatively lower levels of DVL3 protein than resistant tumors.

  6. data (i) support previous the assumption that CK1 acts via phosphorylation of distinct residues as the activator as well as the shut-off signal of Wnt/beta-catenin signaling and (ii) suggest that CK1 acts on Dvl via different mechanism than Fzd5.

  7. High expression of IGFBP7 (show IGFBP7 Proteins) in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta (show TGFB1 Proteins) and Wnt (show WNT2 Proteins) signaling in a Smad2 (show SMAD2 Proteins)/3-Dvl2 (show DVL2 Proteins)/3-dependent manner.

  8. Study showed an association of DVL-1 (show DVL1 Proteins) and DVL-3 with Hirschsprung's disease.

  9. AMPK (show PRKAA1 Proteins) activators suppress cervical cancer cell growth by impairing DVL3 protein synthesis via AMPK (show PRKAA1 Proteins)/mTOR (show FRAP1 Proteins) signaling and/or partially promoting the proteasomal degradation of DVL3

  10. Dvl3 protein transduce signals via the Wnt proteins non canonical pathways, namely via NFAT protein and Src kinase and novel NPM-ALK interacting proteins and possibly NPM-ALK substrates.

DVL3 Protein Profile

Protein Summary

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

Gene names and symbols associated with DVL3

  • dishevelled segment polarity protein 3 (dvl3)
  • dishevelled, dsh homolog 3 (Drosophila) (DVL3)
  • dishevelled 3, dsh homolog (Drosophila) (Dvl3)
  • dishevelled segment polarity protein 3 (DVL3)
  • dishevelled segment polarity protein 3 (Dvl3)
  • dishevelled, dsh homolog 3a (Drosophila) (dvl3a)
  • dsh3 protein
  • dvl3 protein
  • wu:fb75f04 protein
  • wu:fi22h02 protein
  • wu:fp61b09 protein

Protein level used designations for DVL3

DSH homolog 3 , Dishevelled-3 , dishevelled, dsh homolog 3 , dishevelled3 , segment polarity protein dishevelled homolog DVL-3 , dishevelled, dsh homolog 3 (Drosophila) , dishevelled-3 , dishevelled 3 (homologous to Drosophila dsh) , dishevelled 3, dsh homolog , dishevelled 3 , dishevelled, dsh homolog 3a

GENE ID SPECIES
444527 Xenopus laevis
100144702 Xenopus (Silurana) tropicalis
460882 Pan troglodytes
100220188 Taeniopygia guttata
100583216 Nomascus leucogenys
13544 Mus musculus
1857 Homo sapiens
539203 Bos taurus
303811 Rattus norvegicus
424949 Gallus gallus
478650 Canis lupus familiaris
100621038 Sus scrofa
80972 Danio rerio
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