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Dual Specificity Phosphatase 8 Proteins (DUSP8)

The protein encoded by DUSP8 is a member of the dual specificity protein phosphatase subfamily. Additionally we are shipping Dual Specificity Phosphatase 8 Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DUSP8 1850 Q13202
DUSP8 18218 O09112
Rat DUSP8 DUSP8 361679  
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Top Dual Specificity Phosphatase 8 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DUSP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Dual Specificity Phosphatase 8 (DUSP8) Interaction Partners

Human Dual Specificity Phosphatase 8 (DUSP8) interaction partners

  1. The phosphorylation of the M3/6 phosphatase by JNK (show MAPK8 Proteins) in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK (show MAPK8 Proteins) activation.

  2. DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5

  3. Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5.

Dual Specificity Phosphatase 8 (DUSP8) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.

Gene names and symbols associated with DUSP8

  • dual specificity phosphatase 8 (DUSP8)
  • dual specificity phosphatase 8 (dusp8)
  • dual specificity phosphatase 8a (dusp8a)
  • dual specificity protein phosphatase 8 (DSP8)
  • dual specificity phosphatase 8 (Dusp8)
  • dual specificity protein phosphatase 8-like (LOC615727)
  • 5530400B01Rik protein
  • AI593498 protein
  • C11orf81 protein
  • DUSP8 protein
  • Hb5 protein
  • HVH-5 protein
  • HVH8 protein
  • M3/6 protein
  • Nttp1 protein
  • zgc:77593 protein

Protein level used designations for DUSP8

dual specificity phosphatase 8 , dual specificity protein phosphatase 8-like , dual specificity protein phosphatase 8 , H1 phosphatase, vaccinia virus homolog , dual specificity protein phosphatase hVH-5 , serine/threonine specific protein phosphatase , neuronal tyrosine threonine phosphatase 1 , neuronal tyrosine/threonine phosphatase 1

GENE ID SPECIES
100399230 Callithrix jacchus
100541970 Meleagris gallopavo
100562331 Anolis carolinensis
100589601 Nomascus leucogenys
393854 Danio rerio
5721139 Chlamydomonas reinhardtii
1850 Homo sapiens
18218 Mus musculus
361679 Rattus norvegicus
770435 Gallus gallus
615727 Bos taurus
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