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Dynein, Cytoplasmic 1, Light Intermediate Chain 1 Proteins (DYNC1LI1)

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Additionally we are shipping Dynein, Cytoplasmic 1, Light Intermediate Chain 1 Antibodies (36) and Dynein, Cytoplasmic 1, Light Intermediate Chain 1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DYNC1LI1 235661 Q8R1Q8
DYNC1LI1 252902 Q9QXU8
DYNC1LI1 51143 Q9Y6G9
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Top Dynein, Cytoplasmic 1, Light Intermediate Chain 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,488.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DYNC1LI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,

More Proteins for Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1) Interaction Partners

Mouse (Murine) Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1) interaction partners

Human Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1) interaction partners

  1. although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle.

  2. using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway.

  3. Rab11a (show RAB11A Proteins), FIP3 (show IKBKG Proteins) and DLIC-1 form a ternary complex and DLIC-1 colocalises with endogenous FIP3 (show IKBKG Proteins) and Rab11a (show RAB11A Proteins) in A431 cells.

  4. Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint

Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1) Protein Profile

Protein Summary

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores (By similarity).

Gene names and symbols associated with DYNC1LI1

  • dynein cytoplasmic 1 light intermediate chain 1 (Dync1li1)
  • dynein, cytoplasmic 1, light intermediate chain 1 (DYNC1LI1)
  • 1110053F02Rik protein
  • DLCA protein
  • DNCLI1 protein
  • Dnclic1 protein
  • LIC-1 protein
  • LIC1 protein
  • LIC5759 protein

Protein level used designations for DYNC1LI1

DLC-A , cytoplasmic dynein 1 light intermediate chain 1 , dynein light chain A , dynein light intermediate chain 1, cytosolic , dynein, cytoplasmic, light intermediate chain 1 , dynein, cytoplasmic, light intermediate polypeptide 1 , dynein light chain-A , LIC57/59 , dyenin light chain A

GENE ID SPECIES
235661 Mus musculus
252902 Rattus norvegicus
51143 Homo sapiens
420668 Gallus gallus
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