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anti-E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Antibodies

SIAH1 encodes a protein that is a member of the seven in absentia homolog (SIAH) family. Additionally we are shipping SIAH1 Proteins (9) and SIAH1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIAH1 140941 Q920M9
SIAH1 6477 Q8IUQ4
SIAH1    
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Top anti-SIAH1 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184675 staining (0.1µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated EIA, IP, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-SIAH1  Antibody Titration: 1.25 µg/mL ELISA Titer: 1:312500  Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SIAH1 Antibody (Center) in human placenta tissue lysates (35ug/lane).This demonstrates the SIAH1 antibody detected the SIAH1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIAH1 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate Researcher: Peter Brand & Dr. Oliver Kramer, Institute for Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University JenaApplication: Western blottingSpecies+tissue/cell type: Human embryonic kidney 293T How many ug’s of tissue/cell lysate run on the gel: 1:50 µg human HEK-293T cell lysate Primary Antibody dilution: 1:0000Secondary Antibody: Anti-rabbit-IgG Secondary Antibody Dilution: 1:0000 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549/HeLa cells, using SIAH1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated WB SIAH1 Antibody (Center)  western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SIAH1 antibody detected the SIAH1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

SIAH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SIAH1 Antibodies

  1. Cow (Bovine) Polyclonal SIAH1 Primary Antibody for EIA, IP - ABIN782894 : Sroka, Voigt, Deeg, Reed, Schulz, Bhr, Kermer: BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution. in Journal of neurochemistry 2009 (PubMed)
    Show all 5 references for ABIN782894

  2. Human Polyclonal SIAH1 Primary Antibody for EIA, WB - ABIN954801 : Wen, Yang, Song, Li, Yao, Chen, Zhao, Lu, Zhu, Wang: The expression of SIAH1 is downregulated and associated with Bim and apoptosis in human breast cancer tissues and cells. in Molecular carcinogenesis 2010 (PubMed)
    Show all 3 references for ABIN954801

  3. Human Polyclonal SIAH1 Primary Antibody for ELISA, WB - ABIN184675 : Susini, Passer, Amzallag-Elbaz, Juven-Gershon, Prieur, Privat, Tuynder, Gendron, Israël, Amson, Oren, Telerman: Siah-1 binds and regulates the function of Numb. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for ABIN184675

  4. Human Polyclonal SIAH1 Primary Antibody for ELISA, WB - ABIN1533986 : Hu, Chung, Glover, Valentine, Look, Fearon: Characterization of human homologs of the Drosophila seven in absentia (sina) gene. in Genomics 1998 (PubMed)

  5. Cow (Bovine) Polyclonal SIAH1 Primary Antibody for WB - ABIN2778297 : Avraham, Szargel, Eyal, Rott, Engelender: Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against SIAH1 Interaction Partners

Human E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) interaction partners

  1. SIAH1 is associated with a tumor promoting role in breast cancer.

  2. In neuroblastoma cells, siRNA silencing of SIAH1 promoted cellular proliferation and suppressed apoptosis. Protein and mRNA expression of alpha-synuclein, LC3-II and p53 decreased after SIAH1 knockdown. E1 protein and mRNA levels increased after SIAH1 siRNA.

  3. Results demonstrated that miR-107 directly down-regulated SIAH1 expression in human breast cancer cells. An inverse correlation between the expression of miR-107 and SIAH1 was found in human breast cancer tissues and cell lines.

  4. Similar to TAp73, DNp73 is stabilized by hypoxia in a HIF-1a-dependent manner, which otherwise is degraded by Siah1.

  5. findings demonstrate that dissociation of the GAPDH/Siah1 pro-apoptotic complex can block high glucose-induced pericyte apoptosis, widely considered a hallmark feature of DR

  6. Data indicate that ubiquitin ligase Siah as a regulator of to Mesenchymal Transition (EMT (show ITK Antibodies)) by controlling the abundance of the key transcription factor Zeb1 (show ZEB1 Antibodies), while Siah itself is subject to regulation by EMT (show ITK Antibodies)-inducing factors.

  7. miRNA network regulates SIAH1 in in colorectal metastasis tissues.

  8. CDK2 (show CDK2 Antibodies) up-regulates the protein level of KLF10 (show KLF10 Antibodies) through reducing its association with SIAH1, a KLF10 (show KLF10 Antibodies) E3-ubiqutin ligase involved in proteasomal degradation.

  9. molecular basis of Siah1 and Siah2 (show SIAH2 Antibodies) E3 ubiquitin ligase (show MUL1 Antibodies) substrate specificity

  10. Siah1 is a substrate of ASK1 for activation of the GAPDH-Siah1 oxidative stress signaling cascade.

Xenopus laevis E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) interaction partners

  1. two splicing forms, Siah1a and Siah1b, of the Xenopus seven in absentia homolog 1 gene (Siah1) were characterized.

SIAH1 Antigen Profile

Protein Summary

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Gene names and symbols associated with SIAH1

  • E3 ubiquitin-protein ligase Siah1 (Tsp_03055) antibody
  • Protein SIAH-1 (siah-1) antibody
  • seven in absentia 1A (Siah1a) antibody
  • seven in absentia homolog 1 (Drosophila) (siah1) antibody
  • seven in absentia homolog 1 (Drosophila) (SIAH1) antibody
  • siah E3 ubiquitin protein ligase 1 (SIAH1) antibody
  • siah E3 ubiquitin protein ligase 1 (siah1) antibody
  • id:ibd2635 antibody
  • siah antibody
  • Siah1 antibody
  • SIAH1A antibody
  • zgc:56026 antibody

Protein level used designations for SIAH1

E3 ubiquitin-protein ligase Siah1 , E3 ubiquitin-protein ligase SIAH1 , seven in absentia homolog 1 , siah-1 , siah-1a , seven in absentia 1A , seven in absentia-like protein 1

GENE ID SPECIES
10900332 Trichinella spiralis
177138 Caenorhabditis elegans
140941 Rattus norvegicus
80955 Danio rerio
534655 Bos taurus
374076 Gallus gallus
6477 Homo sapiens
443864 Xenopus laevis
487293 Canis lupus familiaris
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