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May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). Additionally we are shipping EML4 Proteins (4) and many more products for this protein.
Showing 10 out of 34 products:
Human Polyclonal EML4 Primary Antibody for ICC, IF - ABIN4307859
Preusser, Berghoff, Ilhan-Mutlu, Magerle, Dinhof, Widhalm, Dieckmann, Marosi, Wöhrer, Hackl, Zöchbauer-Müller, von Deimling, Schoppmann, Zielinski, Streubel, Birner: ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer. in Lung cancer (Amsterdam, Netherlands) 2013
Show all 3 references for 4307859
Human Monoclonal EML4 Primary Antibody for IHC (p), ELISA - ABIN565390
Radtke, Rezaie, Kugler, Zabel, Schultz, Vollmer, Goldmann, Lang: Expression analysis of EML4 in normal lung tissue and non-small cell lung cancer (NSCLC) in the absence and presence of chemotherapeutics. in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2010
We assessed the prevalence of EML4-ALK (show ALK Antibodies) rearrangement gene measured by immunohistochemistry in an unselected population-based consecutive cohort of patients with adenocarcinoma of the lung (ACL (show ACLY Antibodies)), and the correlation with smoking history, thyroid transcription factor 1 (TTF1 (show NKX2-1 Antibodies)), gender and age
Our findings show that group EML4-ALK (show ALK Antibodies) variants 3a/b in non-small cell lung cancer may be a major source of ALK (show ALK Antibodies) inhibitor resistance in the clinic.
EML4-ALK (show ALK Antibodies) rearrangement detection in malignant pleural effusions is a complementary method for EML4-ALK (show ALK Antibodies) detection. VETANA and qRT-PCR are more appropriate for MPE detection. EML4-ALK (show ALK Antibodies) rearrangement in pleural effusions has a predictive value for treatment.
EML4-ALK (show ALK Antibodies)-positive lung cancer is often highly progressive.
case report in which the EML4-ALK (show ALK Antibodies) fusion gene was identified as a second primary lung cancer after surgically resecting EGFR (show EGFR Antibodies) mutation-positive adenocarcinoma
79 (69%) were negative for echinoderm microtubule-associated protein like 4 (EML4)-ALK (show ALK Antibodies) translocation, nine (8%) were positive and 27 (23%) were unevaluable.
Data suggest that platelets are a valuable source for the non-invasive detection of echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (show ALK Antibodies) (EML4-ALK (show ALK Antibodies)) rearrangements and for predicting and monitoring outcome to crizotinib.
Data show that inhibition of echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK (show ALK Antibodies))-mediated stem-like properties enhances the anti-tumor effect.
This review describes the biology of EML4 and ALK (show ALK Antibodies), explains the main features of EML4-ALK (show ALK Antibodies) fusion proteins and outline the therapies that target EML4-ALK (show ALK Antibodies) in cancer. [review]
We further showed that both EML4-ALK (show ALK Antibodies) and mutant forms of EGFR (show EGFR Antibodies) modulate PD-L1 (show CD274 Antibodies) expression via common downstream pathways mediated by MEK (show MAP2K1 Antibodies)-ERK (show EPHB2 Antibodies) and by PI3K (show PIK3CA Antibodies)-AKT (show AKT1 Antibodies).
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).
echinoderm microtubule-associated protein-like 4
, echinoderm microtubule associated protein like 4
, echinoderm microtubule-associated protein-like 4-like
, restrictedly overexpressed proliferation-associated protein
, ropp 120